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| 1 | Noninvasive Label-Free Detection of Cortisol and Lactate Using Graphene Embedded Screen-Printed Electrode显示文摘A sensitive and specific immunosensor for the detection of the hormones cortisol and lactate in human or animal biological fluids, such as sweat and saliva, was devised using the label-free electrochemical chronoamperometric technique. By using these fluids instead of blood,the biosensor becomes noninvasive and is less stressful to the end user, who may be a small child or a farm animal.Electroreduced graphene oxide(e-RGO) was used as a synergistic platform for signal amplification and template for bioconjugation for the sensing mechanism on a screenprinted electrode. The cortisol and lactate antibodies were bioconjugated to the e-RGO using covalent carbodiimide chemistry. Label-free electrochemical chronoamperometric detection was used to analyze the response to the desired biomolecules over the wide detection range. A detection limit of 0.1 ng mL^(-1) for cortisol and 0.1 mM for lactate was established and a correlation between concentration and current was observed. A portable, handheld potentiostat assembled with Bluetooth communication and battery operation enables the developed system for point-of-care applications. A sandwich-like structure containing the sensing mechanisms as a prototype was designed to secure the biosensor to skin and use capillary action to draw sweat or other fluids toward the sensing mechanism. Overall, the immunosensor shows remarkable specificity, sensitivity as well as the noninvasive and point-of-care capabilities and allows the biosensor to be used as a versatile sensing platform in both developed and developing countries. | Satish K.Tuteja Connor Ormsby Suresh Neethirajan | 2018 | Nano-Micro Letters2018，10，3： | 3 |
| 2 | Microfluidics: Rapid Diagnosis for Breast Cancer显示文摘Breast cancer affected 1.7 million people worldwide in 2012 and accounts for approximately 23.3 % of all cancers diagnosed in women. The disease is characterized by a genetic mutation, either inherited or resulting from environmental factors, that causes uncontrollable cellular growth of breast tissue or adjacent tissues. Current means of diagnosing this disease depend on the individual analyzing the results from bulky, highly technical, and expensive equipment that is not globally accessible. As a result, patients can go undiagnosed due to a lack of available equipment or be overdiagnosed due to human error. This review attempts to highlight current means of diagnosing breast cancer and critically analyze their effectiveness and usefulness in terms of patient survival. An alternative means based on microfluidics biomarker detection is then presented. This method can be considered as a primary screening tool for diagnosing breast cancer based on its robustness, high throughput, low energy requirements, and accessibility to the general public. | Satvinder Panesar Suresh Neethirajan | 2016 | Nano-Micro Letters2016，8，3： | 3 |
| 3 | Detection techniques for stored-product insects in grain显示文摘 | Neethirajan S Karunakaran C Jayas D S | 2007 | Food Control2007，18，2： | 1 |
| 4 | Detection techniques for stored product insects in grain显示文摘 | Neethirajan S Karunakaran C Jayas D S | 2007 | Food Control2007，18，2： | 1 |
| 5 | Detection techniques for stored-product insects in grain显示文摘 | NEETHIRAJAN S KARUNAKARAN C JAYAS D S | 2007 | Food control2007，18，2： | 1 |
| 6 | Evaluation of the effect of moisture content on cereal grains by digital imageanalysis显示文摘 | Tahir A R Neethirajan S Jayas D S | 2007 | Food Research International2007，40，： | 1 |
| 7 | Classification of vitreousness in durum wheat using soft X-rays and trans-mitted light images显示文摘 | Neethirajan S Karunakaran C Symons S | 2006 | Computers and Electronics in Agriculture2006，53，1： | 1 |
| 8 | Detection techniques for stored-product insects in grain显示文摘 | Neethirajan S Karunakaran C Jayas D S | 2007 | Food Control2007，18，2： | 1 |
| 9 | Evaluation of the effect of moisture content on cereal grains by digital image analysis显示文摘 | Tahir A R Neethirajan S Jayas D S | 2007 | Food Research International2007，40，： | 1 |
| 10 | A homogenous fluorescence quenching based assay for specific and sensitive detection of influenza virus A hemagglutinin antigen显示文摘 | CHEN L NEETHIRAJAN S | 2015 | Sensors(Basel)2015，15，4： | 1 |
| 11 | Genotype/phenotype association in Indian congenital aniridia显示文摘 | Neethirajan G Solomon A Krishnadas SR | 2009 | Indian J Pediatr2009，76，5： | 1 |
| 12 | Detection techniques for stored-product insects in grain显示文摘 | Neethirajan S Karunakaran C Jayas D S | 2007 | Food Control2007，18，2： | 1 |
| 13 | Development of carbon dioxide (COz) sensor for grain quality monitoring显示文摘 | Neethirajan S Freund M S Jayas D S | 2010 | Bi- osystems Engineering2010，106，39： | 1 |
| 14 | Genotype/phenoty peasso- ciation in Indian congenital aniridia 显示文摘 | NEETHIRAJAN G SOLOMON A KRISHNADAS SR VIJAY- ALAKSHMI P SUNDARESAN P | 2009 | Indian J Pediatr2009，76，5： | 1 |
| 15 | Detection techniques for stored-product insects in grain显示文摘 | Neethirajan S Karunakaran C Jayas D S | 2007 | Food Control2007，，18： | 1 |
| 16 | Evaluation of the effect of moisture content on cereal grains by digital image analysis 显示文摘 | Tahir A R Neethirajan S Jayas D S | 2007 | Food Research International2007，40，11： | 1 |
| 17 | Detection of sprouted wheat kernels using soft X-ray image analysis 显示文摘 | Neethirajan S Jayas D S White N D G | 2007 | Journal of Food Engineering2007，81，50： | 1 |
| 18 | Detection techniques for stored-product insects in grain显示文摘 | Neethirajan S Karunakaran C Jayas D S | 2007 | Food Control2007，18，2： | 1 |
| 19 | Detection techniques for stored-product insects in grain显示文摘 | Neethirajan S Karunakarn C Jayas D S | | 0，，02： | 1 |
| 20 | Development of carbon dioxide(CO2)sensor for grain quality monitoring显示文摘 | Neethirajan S Freund M S Jayas D S | 2010 | Biosystems Engineering2010，106，： | 1 |
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