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| 1 | Diffusion-weighted and diffusion-tensor imaging of normal and diseased uterus显示文摘Owing to technical advances and improvement of the software, diffusion weighted imaging and diffusion tensor imaging(DWI and DTI) greatly improved the diagnostic value of magnetic resonance imaging(MRI) of the pelvic region. These imaging sequences can exhibit important tissue contrast on the basis of random diffusion(Brownian motion) of water molecules in tissues. Quantitative measurements can be done with DWI and DTI by apparent diffusion coefficient(ADC) and fractional anisotropy(FA) values respectively. ADC and FA values may be changed by various physiological and pathological conditions providing additional information to conventional MRI. The quantitative DWI assists significantly in the differentiation of benign and malignant lesions. It can demonstrate the microstructural architecture and celluler density of the normal and diseased uterine zones. On the other hand, DWI and DTI are useful for monitoring the treatment outcome of the uterine lesions. In this review, we discussed advantages of DWI and DTI of the normal and diseased uterus. | Duygu Kara Bozkurt Murat Bozkurt Mehmet Ali Nazli Ilhan Nahit Mutlu Ozgur Kilickesmez | 2015 | World Journal of Radiology2015，7，7： | 9 |
| 2 | Diagnosis and treatment of gallbladder perforation显示文摘AIM: To present our clinical experience with gallbladder perforation cases. METHODS: Records of 332 patients who received medical and/or surgical treatment with the diagnosis of acute cholecystitis in our clinic between 1997 and 2006 were reviewed retrospectively. Sixteen (4.8%) of those patients had gallbladder perforation. The parameters including age, gender, time from the onset of symptoms to the time of surgery, diagnostic procedures, surgical treatment, morbidity, and mortality were evaluated. RESULTS: Seven patients had typeⅠgallbladder perforation, 7 type Ⅱ gallbladder perforation, and 2 type Ⅲ gallbladder perforation according to Niemeier’ s classification. The patients underwent surgery after administration of intravenous electrolyte solutions, and were treated with analgesics and antibiotics within the first 36 h (mean 9 h) after admission. Two patients died of sepsis and multiple organ failure in the early postoperative period. Subhepatic abscess, pelvic abscess, pneumonia, pancreatitis, and acute renal failure were found in 6 patients. CONCLUSION: Early diagnosis and emergency surgical treatment of gallbladder perforation are of crucial importance. Upper abdominal computerized tomography for acute cholecystitis patients may contribute to the preoperative diagnosis of gallbladder perforation. | Hayrullah Derici Cemal Kara Ali Dogan Bozdag Okay Nazli Tugrul Tansug Esra Akca | 2006 | World Journal of Gastroenterology2006，12，48： | 9 |
| 3 | Metastasis in renal cell carcinoma:Biology and implications for therapy显示文摘Although multiple advances have been made in systemic therapy for renal cell carcinoma(RCC),metastatic RCC remains incurable.In the current review,we focus on the underlying biology of RCC and plausible mechanisms of metastasis.We further outline evolving strategies to combat metastasis through adjuvant therapy.Finally,we discuss clinical patterns of metastasis in RCC and how distinct systemic therapy approaches may be considered based on the anatomic location of metastasis. | Jun Gong Manuel Caitano Maia Nazli Dizman Ameish Govindarajan Sumanta K.Pal | 2016 | Asian Journal of Urology2016，3，4： | 7 |
| 4 | Importance of antimicrobial susceptibility testing for the management of eradication in Helicobacter pylori infection显示文摘The management of Helicobacter pylori(H. pylori) infection treatment differs from the common treatment protocol for other infectious diseases. Because culture-or molecular-guided approaches face several practical issues, such as the invasive procedures required to obtain gastric biopsy specimens and the lack of availability of routine laboratory testing in some places, H. pylori treatment includes the administration of two or three empirically selected antibiotics combined with a proton pump inhibitor rather than evidence-based eradication treatment. The efficacy of empirical therapy is decreasing, mostly due to increasing multiple resistance. Multiresistance to levofloxacin, clarithromycin, and metronidazole, which are commonly used in empirical treatments, appears to have increased in many countries. Mutations play a primary role in the antimicrobial resistance of H. pylori, but many different mechanisms can be involved in the development of antibiotic resistance. Determining and understanding these possible mechanisms might allow the development of new methods for the detection of H. pylori and the determination of antimicrobial resistance. A treatment based on the detection of antimicrobial resistance is usually more effective than empirical treatment. Nevertheless, such an approach before treatment is still not recommended in the Maastricht guidelines due to the difficulty associated with the routine application of available cultureor molecular-based susceptibility tests, which are usually administered in cases of treatment failure. The management of first and rescue treatments requires further research due to the steadily increase in antimicrobial resistance. | Nazli Arslan ozlem Yilmaz Ebru Demiray-Gürbüz | 2017 | World Journal of Gastroenterology2017，23，16： | 7 |
| 5 | Effects of bee propolis supplementation on glycemic control, lipid profile and insulin resistance indices in patients with type 2 diabetes: a randomized, double-blind clinical trial显示文摘BACKGROUND:Propolis,a natural resinous substance made by bees from material extracted from plants,flowers and bee's wax,has shown great therapeutic effects and been widely used in food and drug industries.Recently,some researchers have studied the effect of this substance in the treatment of diabetes.OBJECTIVE:The purpose of this trial was to determine the effect of bee propolis on glycemic control,serum lipid profile and insulin resistance indices in patients with type 2 diabetes(T2D).DESIGN,SETTING,PARTICIPANTS AND INTERVENTIONS:This randomized clinical trial involved 66 patients with T2 D,which were randomly divided into two groups of intervention(IG) and placebo(PG).IG received 300 mg three times a day for a total of 900 mg/d of propolis pills,while PG received similar pills,lacking propolis,on the same schedule for 12 weeks.MAIN OUTCOME MEASURES:Fasting blood glucose(FBG),hemoglobin A1c(HbA1c),total cholesterol(TC),low-density lipoprotein(LDL),high-density lipoprotein(HDL),triglyceride(TG),serum insulin and insulin resistance indices were the main outcome measures.RESULTS:The mean change in FBG between the IG((17.76 ± 27.72) mg/dL decrease) and the PG((6.48 ± 42.77) mg/dL increase) was significantly different(P= 0.01).Change in mean HbA1 c had a similar pattern to FBG.The mean change in TC between the IG((5.16 ± 43.80) mg/dL increase) and the PG((28.9 ± 27.4) mg/dL increase) was also significantly different(P= 0.01),showing the protective role of propolis against the increase in TC.The change in mean LDL was similar to mean TC.There was no significant difference in other lipids or insulin resistance indices between the two groups.CONCLUSION:Based on this study,the daily intake of 900 mg of bee propolis supplement for 12 weeks results in improvement of glycemic and some serum lipid levels in patients with T2 D.TRIAL REGISTRATION:This study is registered on the website of Iranian Ministry of Health(www.irct.ir)with proprietary code of IRCT2014080218659N1. | Nazli Samadi Hassan Mozaffari-Khosravi Masoud Rahmanian Mohsen Askarishahi | 2017 | Journal of Integrative Medicine2017，15，2： | 6 |
| 6 | Synthesis, physicochemical characterizations and catalytic performance of Pd/carbon-zeolite and Pd/carbon-Ce02 nanocatalysts used for total oxidation of xylene at low temperatures显示文摘 | Zeinab JAMALZADEH | 2013 | Frontiers of Environmental Science & Engineering2013，7，3： | 5 |
| 7 | Correlation of neutrophil/lymphocyte and platelet/lymphocyte ratio with visual acuity and macular thickness in age-related macular degeneration显示文摘AIM:To investigate the place of neutrophil-to-lymphocyte ratio(NLR) and platelet-to-lymphocyte ratio(PLR) in the diagnosis of and prognosis for neovascular age-related macular degeneration(AMD). METHODS:One hundred AMD patients and 100 healthy controls were included in the study. Blood samples were obtained from the venous blood, which is used for routine analysis, and these samples were subjected to complete blood count. NLR was defined as the neutrophil count divided by the number of lymphocytes, and PLR was defined as the platelet count divided by the number of lymphocytes. RESULTS:No statistically significant difference was observed between the two groups under consideration in terms of demographic features(P>0.05). The average NLR in the patient group was found to be significantly higher than that in the healthy control group(P<0.05). The average PLR was significantly higher in the patient group as compared to the control group(P<0.05). As best corrected visual acuity(BCVA) increased, both NLR and PLR decreased(significant negative correlations at 49.8% and 63.0%, respectively), whereas as central macular thickness(CMT) increased, both NLR and PLR increased(significant positive correlations at 59.3% and 70.0%, respectively).CONCLUSION:NLR and PLR levels are higher among neovascular AMD patients as compared to healthy control group. NLR and PLR levels were found to be inversely proportional to BCVA and directly proportional to CMT. | Elvan Alper Sengul Ozgur Artunay Alev Kockar Ceyda Afacan Rifat Rasier Palmet Gun Nazli Gul Yalcin Erdal Yuzbasioglu | 2017 | International Journal of Ophthalmology(English edition)2017，10，5： | 4 |
| 8 | 自体血清滴眼液对屈光性角膜切削术后角膜上皮愈合的影响(英文)显示文摘目的:研究自体血清滴眼液对屈光性角膜切削术(PRK)后角膜上皮愈合的影响。方法:本研究共纳入20例40眼近视及近视散光患者,其中男性9例,女性11例。每例患者随机选取一眼作为研究组应用20%含自体血清的人工泪液,另一眼为对照组应用常规人工泪液。PRK术中,40眼均于角膜表面居中放置直径8 mm的酒精储槽, 20%的酒精作用20s。术后每天观察直到角膜上皮愈合后,分别于1mo,6mo,12mo进行随访。上皮愈合时间为主要观察指标,并记录裸眼视力(UCVA),显然验光和混浊度。结果:两组间术前小瞳检影结果无明显差异。术后1d,2d,3d,研究组平均疼痛评分均显著低于对照组(P<0.05)。术后1d,3d,研究组的平均水平和垂直上皮缺损低于对照组(P<0.05)。研究组上皮完全愈合的平均时间比对照组短约0.7d(3.15±0.366d vs 3.85±0.587d,P=0.00)。结论:研究表明,应用自体血清滴眼液,通过加速角膜上皮愈合和减轻疼痛,从而缩短视力恢复时间,降低屈光性角膜切削术术后不适、混浊度和感染风险。 | Ali Mostafaei Behzad Fallahi Motlagh Nazli Taheri Siamak Nejatbakhsh | 2019 | 国际眼科杂志2019，19，4： | 3 |
| 9 | Interferon-β induced in female genital epithelium by HIV-1 glycoprotein 120 via Toll-like-receptor 2 pathway acts to protect the mucosal barrier显示文摘More than 40%of HIV infections occur via female reproductive tract(FRT)through heterosexual transmission.Epithelial cells that line the female genital mucosa are the first line of defense against HIV-1 and other sexually transmitted pathogens.These sentient cells recognize and respond to external stimuli by induction of a range of carefully balanced innate immune responses.Previously,we have shown that in response to HIV-1 gp120,the genital epithelial cells(GECs)from upper reproductive tract induce an inflammatory response that may facilitate HIV-1 translocation and infection.In this study,we report that the endometrial and endocervical GECs simultaneously induce biologically active interferon-β(IFNβ)antiviral responses following exposure to HIV-1 that act to protect the epithelial tight junction barrier.The innate antiviral response was directly induced by HIV-1 envelope glycoprotein gp120 and addition of gp120 neutralizing antibody inhibited IFNβproduction.Interferon-βwas induced by gp120 in upper GECs through Toll-like receptor 2 signaling and required presence of heparan sulfate on epithelial cell surface.The induction of IFNβwas dependent upon activation of transcription factor IRF3(interferon regulatory factor 3).The IFNβwas biologically active,had a protective effect on epithelial tight junction barrier and was able to inhibit HIV-1 infection in TZM-bl indicator cells and HIV-1 replication in T cells.This is the first report that recognition of HIV-1 by upper GECs leads to induction of innate antiviral pathways.This could explain the overall low infectivity of HIV-1 in the FRT and could be exploited for HIV-1 prophylaxis. | Aisha Nazli Sara Dizzell Muhammad Atif Zahoor Victor H Ferreira Jessica Kafka Matthew William Woods Michel Ouellet Ali A Ashkar Michel J Tremblay Dawn ME Bowdish Charu Kaushic | 2019 | Cellular & Molecular Immunology2019，16，2： | 2 |
| 10 | 热脱水钠硼解石在醋酸铵溶液中的溶解(英文)显示文摘钠硼解石含有大量的结晶水。采用煅烧法可以将固体组分中的一部水脱去,得到一种多孔结构物质,以提高浸出反应速率。采用醋酸铵作为浸出溶剂,研究煅烧钠硼解石样品在不同温度下的溶解情况。研究了反应参数对煅烧钠硼解石溶解的影响。研究发现,煅烧样品的溶解速率高于未煅烧样品的溶解速率。在煅烧温度低于150℃时,煅烧钠硼解石的溶解速率随着煅烧温度的升高而加快。钠硼解石的浸出反应速率符合化学反应控制模型。溶解过程中的活化能为41.5kJ/mol。 | Nizamettin DEMRKIRAN Nazli BAYRAKCI Celal ASN | 2013 | 中国有色金属学会会刊:英文版2013，23，6： | 2 |
| 11 | Percutaneous Nephrolithotomy: Variables That Influence Hemorrhage显示文摘 | Burak Turna Oktay Nazli Serkan Demiryoguran Rashad Mammadov Cag Cal | 2007 | Urology2007，，4： | 2 |
| 12 | 土耳其文版低视力生活质量量表的效度和信度研究(英文)显示文摘目的:把低视力相关的生活质量(LVQOL)文书改编为土耳其文,并评估其效度和信度。方法:这项研究是在387位参加安卡拉大学医学院,低视力康复中心的患者中进行的。使用Spearman相关系数,Cronbachα系数和验证性因素分析(CFA)进行统计分析。结果:根据CFA结果,在'调节能力'维的条目,因为有低于0.40的因子负荷故被排除在调查问卷之外。根据Cronbachα系数,对量表的信度进行了评估。'远视力,移动和光感'维的信度是α=0.863;'调节能力'维是α=0.694;'读和精细工作'α=0.791,'日常生活能力'α=0.770。因此,这些结果表明,用量表来衡量低视力患者的视力相关的生活质量是可靠的。对维之间的相关性也进行了分析,'调节能力'和'读和精细工作'之间的相关性被认为是最低的(rs=0.336,P<0.01),而'读和精细工作'与'日常生活能力'之间的相关性被发现是最强的。此外,'调节能力'仅与'远视力,移动和光感'表现最强的相关性。结论:删除第二个维中最后一个条目后,对LVQOL所有维的土耳其文改编已被证明是可靠的,有效的,适合在土耳其的低视力患者中使用。 | Aysun Idil Mehmet Ozen Nazli Atak Atilla Elhan Selcen Pehlivan | 2011 | 国际眼科杂志2011，11，11： | 2 |
| 13 | Fatty acids of lamb meat from two breeds fed different forage: concentrate ratio 显示文摘 | Demirel G Ozpinar H Nazli B | 2006 | Meat Science2006，72，： | 1 |
| 14 | Accumulation of tobacco mosaic virus (TMV) at different depths clay and loamy sand textural soils due to tobacco waste application显示文摘 | Copkun Gulser Nazly Kutluk Yylmaz Feride Candemir | 2008 | Environmental Monitoring and Assessment2008，146，1： | 1 |
| 15 | Enterocyte cytoskeleton changes are crucial for enhanced translocation of nonpathogenic escherichia coli across metabolically stressed gut epithelia显示文摘 | Nazli A Wang A Steen O | 2006 | Infect Immune2006，74，1： | 1 |
| 16 | Juxtadrenal schwannoma显示文摘 | Nazli O Cal C Hekimgil M | 1998 | Int U rol Nephrol1998，，： | 1 |
| 17 | Percutaneous nephrolithotomy: variables that influence hemorrhage 显示文摘 | Tuma B Nazli D Demiryoguran S | 2007 | Urology2007，69，4： | 1 |
| 18 | Room temperature, metal-free synthesis of diaryl ethers with use of diaryliodonium salts 显示文摘 | Nazli Jalalian Eloisa E Ishikawa Luiz F Silva Jr | 2011 | Org Lett2011，13，6： | 1 |
| 19 | Percutaneous nep- hrolithotomy : variables that influence hemorrhage 显示文摘 | Turna B Nazli O Demiryoguran S | 2007 | Urology2007，69，4： | 1 |
| 20 | Percutaneous nephrolithotomy:variables that influence hemorrhage显示文摘 | Turna B Nazli O Demiryoguran S | | 0，，04： | 1 |
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