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| 1 | Evaluation of extracts and essential oil from Callistemon viminalis leaves:Antibacterial and antioxidant activities,total phenolic and flavonoid contents显示文摘Objective:To investigate antioxidant and antibacterial activities of Callistemon viminalis(C.viminalis)leaves.Methods:The essential oil of C.viminalis leaves obtained by hydrodistillation was analyzed by GC/MS.Different extracts were tested for total phenolic and flavonoid contents and in vitro antioxidant(DPPH assay)and antibacterial(agar disc diffusion and 96-well micro-plates methods)actives.Results:Fourteen components were identified in the essential oil,representing 98.94%of the total oil.The major components were 1,8-cineole(64.53%)andα-pinene(9.69%).Leaf essential oil exhibited the highest antioxidant activity of(88.60±1.51)%comparable to gallic acid,a standard compound[(80.00±2.12)%].Additionally,the biggest zone of inhibitions against the studied bacterial strains was observed by the essential oil when compared to the standard antibiotic(tetracycline).The crude methanol extract and ethyl acetate fraction had a significant antibacterial activity against the tested bacterial strains.Conclusions:It can be suggested that C.viminalis is a great potential source of antibacterial and antioxidant compounds useful for new antimicrobial drugs from the natural basis.The present study revealed that the essential oil as well as the methanol extracts and ethyl acetate fraction of C.viminalis leaves exhibited highly significant antibacterial activity against the tested bacterial strains. | Mohamed ZM Salem Hayssam M Ali Nader A El-Shanhorey Ahmed Abdel-Megeed | 2013 | Asian Pacific Journal of Tropical Medicine2013，6，10： | 14 |
| 2 | Preemptive mechanical ventilation can block progressive acute lung injury显示文摘Mortality from acute respiratory distress syndrome(ARDS) remains unacceptable, approaching 45% in certain high-risk patient populations. Treating fulminant ARDS is currently relegated to supportive care measures only. Thus, the best treatment for ARDS may lie with preventing this syndrome from ever occurring. Clinical studies were examined to determine why ARDS has remained resistant to treatment over the past several decades. In addition, both basic science and clinical studies were examined to determine the impact that early, protective mechanical ventilation may have on preventing the development of ARDS in at-risk patients. Fulminant ARDS is highly resistant to both pharmacologic treatment and methods of mechanical ventilation. However, ARDS is a progressive disease with an early treatment window that can be exploited. In particular, protective mechanical ventilation initiated before the onset of lung injury can prevent the progression to ARDS. Airway pressure release ventilation(APRV) is a novel mechanical ventilation strategy for delivering a protective breath that has been shown to block progressive acute lung injury(ALI) and prevent ALI from progressing to ARDS. ARDS mortality currently remains as high as 45% in some studies. As ARDS is a progressive disease, the key to treatment lies with preventing the disease from ever occurring while it remains subclinical. Early protective mechanical ventilation with APRV appears to offer substantial benefit in this regard and may be the prophylactic treatment of choice for preventing ARDS. | Benjamin Sadowitz Sumeet Jain Michaela Kollisch-Singule Joshua Satalin Penny Andrews Nader Habashi Louis A Gatto Gary Nieman | 2016 | World Journal of Critical Care Medicine2016，5，1： | 9 |
| 3 | 在有煽动性、非煽动性的腹的疼痛显型的孩子的 interleukin-6 和桅杆房间的反的关系显示文摘 AIM: To investigate interleukin-6 (IL-6), mast cells, enterochromaffin cells, 5-hydroxytryptamine, and substance P in the gastrointestinal mucosa of children with abdominal pain. METHODS: Formalin-fixed paraffin-embedded gas-trointestinal biopsy blocks from patients (n = 48) with non-inflammatory bowel disease (irritable bowel syndrome and functional abdominal pain) and inflammatory bowel disease were sectioned and stained for IL-6, mast cells, enterochromaffin cells, 5-hydroxytryptamine, and substance P. All children had chronic abdominal pain as part of their presenting symptoms. Biopsy phenotype was confirmed by a pathologist, blinded to patient information. Descriptive statistics, chi-square, and independent sample t tests were used to compare differences between the inflammatory and non-inflammatory groups. RESULTS: The cohort (n = 48), mean age 11.9 years (SD = 2.9), 54.2% females, 90% Caucasian, was comprised of a non-inflammatory (n = 26) and an inflammatory (n = 22) phenotype. There was a significant negative correlation between substance P expression and mast cell count (P = 0.05, r = -0.373). Substance P was found to be expressed more often in female patient biopsies and more intensely in the upper gastrointestinal mucosa as compared to the lower mucosa. There were significantly increased gastrointestinal mucosal immunoreactivity to IL-6 (P = 0.004) in the inflammatory phenotype compared to non-inflammatory. Additionally, we found significantly increased mast cells (P = 0.049) in the mucosa of the non-inflammatory phenotype compared to the inflammatory group. This difference was particularly noted in the lower colon biopsies. CONCLUSION: The findings of this study yield preliminary evidence in identifying biomarkers of undiagnosed abdominal pain in children and may suggest candidate genes for future evaluation. | Wendy A Henderson Ravi Shankar Tara J Taylor Arseima Y Del Valle-Pinero David E Kleiner Kevin H Kim Nader N Youssef | 2012 | World Journal of Gastrointestinal Pathophysiology2012，3，6： | 2 |
| 4 | Dynamic stress concentrations for an axially loaded strut at discontinuities due to an elliptical hole or double circular notches显示文摘 | WILLIAM A NADER Z WALTER N | 2004 | International Journal of Impact Engineering2004，30，3： | 1 |
| 5 | Finite difference approach for consolidation with variable compressibility and permeability 显示文摘 | NADER A HASSAN R AKBAR A | 2007 | Computers and Geotechnics2007，，34： | 1 |
| 6 | Mitolane has an estrogenic effect on sex hornnme-binding globulin and cnrtieosternid-binding globulin in humans 显示文摘 | Nader N Raverot ( Emptoz-Bonnelon A el al | 2006 | J Clia Endocrinnl Metab2006，91，： | 1 |
| 7 | Effects of maceration of rice straw on voluntary intake and performance of growing beef cattle fed rice straw-based rations 显示文摘 | Nader G A Robinson P H | 2008 | Animal Feed Science and Technology2008，146，12： | 1 |
| 8 | Tuber hydroforming of automotive side members with extruded aluminium profiles显示文摘 | Nader A Tomas N Gunnar L | 2003 | Journal of Materials Processing Technology2003，142，1： | 1 |
| 9 | Detection and analysis of two serotypes of ammonia-oxidizing bacteria in sewage plants by flow cytometry显示文摘 | VOLSCH A NADER W F GEISS H K | 1990 | Applied and Environment Microbiology1990，56，8： | 1 |
| 10 | Transversus abdominis plane block to ameliorate postoperative pain outcomes after laparoscopic surgery: a meta-analysis of randomized controlled trials显示文摘 | De Oliveira GS Jr Castro-Alves LJ Nader A | 2014 | Anesth Analg2014，118，2： | 1 |
| 11 | Trans- versus abdominis plane block to ameliorate postoperative pain outcomes after laparoscopic surgery : a meta-analysis of randomized controlled trials 显示文摘 | De Oliveira GS Jr Castro-Alves LJ Nader A | 2014 | Anesth Analg2014，118，2： | 1 |
| 12 | Understanding the stability in ater of mesoporous SBA-15 and MCM-41 显示文摘 | Galarneau A Nader M Guenneau F | 2007 | Journal of Physical Chemistry C2007，111，23： | 1 |
| 13 | Shaking table test or rigid, semirigid,and flexible steel frames 显示文摘 | NADER M N ASTANEH-ASL A | 1996 | Journal of Structural Engineering ASCE1996，122，6： | 1 |
| 14 | An Analytical and Numerical Study of Solar Chimney Use for Room Natural Ventilation显示文摘 | Ramadan B Nader S A K | 2008 | Energy and Buildings2008，40，5： | 1 |
| 15 | Intestinal cytokine gene expression in infant swith acute nerrotizing enterocolitis: interleukin-11 mRNA expression inverserly correlate with extent of disease显示文摘 | Nader EP Stanford A Zhang XR | 2001 | J Pediatr Surg2001，36，8： | 1 |
| 16 | Transversus abdominis plane block to ameliorate postoperative pain outcomes after laparoscopic surgery: a meta-analysis of randomized controlled trials显示文摘 | De-Oliveira G S Jr Castro-Alves L J Nader A | 2014 | Anesth Analg2014，118，2： | 1 |
| 17 | Physical, sexual, and psychological violence in a gynaecological-psychosomatic outpatient sample: Prevalence and implications for mental health显示文摘 | Leithner K Assem-Hilger E~ Naderer A | 2009 | Eur J Obstet Gynecol Reprod Biol2009，144，2： | 1 |
| 18 | Physical, sexual, and psychological violence in a gynaecological-psychosomatic outpatient sample: Prevalence and implications for mental health显示文摘 | Leithner K Assem Hilger E Naderer A | 2009 | Eur J Obst Gynecol Reprod Biol2009，144，2： | 1 |
| 19 | On Strength, Stiffness and Dent Resistance of Carbody Panels 显示文摘 | NADER A | 1995 | Journal of Material Process Technology1995，，1： | 1 |
| 20 | Antithyroid peroxidase antibodies in patients with high normal range thyroid stimulating hormone显示文摘 | Zelaya AS Stotts A Nader S | 2010 | Fain Med2010，42，2： | 1 |
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