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| 1 | Short-term treatment with proton-pump inhibitors as test for gastoesophageal reflux disease:a Meta-analysis of diagnostic test characteristics显示文摘 | Numans ME Lau J De-Wtt NJ | | 0，，： | 1 |
| 2 | Short-term treatment with proton-pump inhibitors as a test for gastroesophageal reflux disease:a mete-analysis of diagnostic test characteristics显示文摘 | Numans ME Lau J de Wit NJ | 2004 | Ann Intern Med2004，140，7： | 1 |
| 3 | Effect of proton-pump inhibitor treatment on symptoms and quality of life in GERD patients depends on the symptom-reflux association 显示文摘 | Aanen MC Weusten BL Numans ME | 2008 | J Clin Gastroentero12008，42，5： | 1 |
| 4 | 显示文摘 | Quartero AO Post MWM Numans ME | 1999 | Gut1999，45，： | 1 |
| 5 | Nuclear to cytoplas-mic compartment shift of the P33INGlb tumor suppressor protein is associated with malignancy in melanocytic lesions显示文摘 | Numan GS Anderson J J Mathers ME | 2002 | Histopatholo- gy2002，40，： | 1 |
| 6 | Diagnostic value of the reflux disease questionnaire in general practice显示文摘 | Aanen MC Numans ME Weusten BL Smout AJ | 2006 | Digestion2006，74，34： | 1 |
| 7 | Short-term treatment with proton pump inhibitors, H2-receptor antagonists and prokinetics for gastrooesophageal reflux disease-like symptoms and endoscopy negative reflux disease显示文摘 | van Pinxteren B Numans ME Bonis PA | 2004 | Cochrane Database Syst Rev2004，18，00： | 1 |
| 8 | Short-term treatment with proton-pump inhibitors as a test for gastroesophageal reflux disease:a meta-analysis of diagnostic test characteristics显示文摘 | NUMANS ME LAU J DE WIT NJ | 2010 | Ann Intern Med2010，140，： | 1 |
| 9 | Diagnostic value of the proton pump inhibitor test for gastro-oesophageal reflux disease in primary care显示文摘 | AANEN MC WEUSTEN BL NUMANS ME | 2006 | Aliment Pharmacol Ther2006，24，： | 1 |
| 10 | Short-term treatment with proton-pump inhibitors as a test for gastroesophageal reflux disease:ameta-analysis of diagnostic test characteristics 显示文摘 | Numans ME Lau J de Wit NJ | 2004 | Ann Intern Med2004，140，7： | 1 |
| 11 | Trends and determinants of ade- quate gastmprotection in patients chronically using NSAIDs 显示文摘 | Helsper CW Smeets HM Numans ME | 2009 | Phar- macoepidemiol Drug Saf2009，18，： | 1 |
| 12 | Short-term treatment with PPIs as a test for gastroesophageal reflux disease: a meta-analysis of diagnostic test charaeteristies 显示文摘 | Numans ME Lau J de Wit NJ | 2004 | Ann Intern Med2004，140，7： | 1 |
| 13 | Nuclear to cytoplasmic compartment shift of the P33ING1b tumor suppressor protein is asso-ciated with malignancy in melanocytie lesions显示文摘 | Numan GS Anderson JJ Mathers ME | 2002 | Histopathology2002，40，： | 1 |
| 14 | Short-term treatment with proton-pump inhibitors as a test for gastroesophageal reflux disease: a meta-analysis of diagnostic test characteristics 显示文摘 | Numans ME Lau J de Wit N J | 2004 | Ann Intern Med2004，140，7： | 1 |
| 15 | A randomised controlled trial of four management strategies for dyspepsia: relationships between symptom subgroups and strategy outcome显示文摘 | Lewin van den Broek NT Numans ME Buskens E | 2001 | Br J Gen Pract2001，51，469： | 1 |
| 16 | Short-term treatment with proton pump inhibitors,H2-receptorantagonists and prokinetics for gastro-oesophageal refluxdisease-like symptoms and endoscopy negative refluxdisease显示文摘 | Van Pinxteren B Numans ME Bonis PA | 2004 | Cochrane Database Syst Rev2004，18，00： | 1 |
| 17 | 短疗程质子泵抑制剂、H_2受体拮抗剂及促动力药物治疗胃食道反流样症状及内镜检查阴性的反流病(摘要)显示文摘胃食管反流(gastro-oesophageal reflux disease,GORD)的发病率有上升的趋势。临床主要表现为烧心、反酸、胸骨后疼痛等。GORD的处理包括初步诊断及病情严重程度的评估、尽快控制症状及选择长期治疗方案三个阶段。因为60%的GORD内镜检查阴性(endoscopy negative reflux disease,ENRD),治疗的目的及疗效的评估应以症状为主。药物治疗包括H2受体拮抗剂、质子泵抑制剂及促动力剂等。目前的治疗策略包括药物递减及递增两种方式。大多数研究显示,对于症状控制或维持治疗,质子泵抑制剂疗效较H2受体拮抗剂及促动力剂要好。对于ENRD的长期治疗,间歇给药或按症状给药也可取得较好的疗效,且可降低费用。鉴于我国该病的病情较欧美相对较轻,实际用药可根据患者病情严重程度及经济状态加以选择。 | Van Pinxteren B Numans ME Bonis PA Lau J 尉秀清 | 2003 | 循证医学2003，3，2： | 1 |
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