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| 1 | T4 cervical esophageal cancer cured with modern chemoradiotherapy: A case report显示文摘BACKGROUND T4 esophageal cancer portends a poor prognosis,particularly when it is complicated by a tracheoesophageal fistula(TEF)either resulting from disease or occurring as a complication of treatment.Patients with TEF that occurs during treatment are commonly treated with palliative intent because fistula-associated treatment complications such as aspiration pneumonia and mediastinitis are associated with high morbidity and mortality.To date,there is no clear evidence on the optimal treatment of T4 esophageal cancer,particularly when a TEF formation occurs.CASE SUMMARY A 67-year-old gentleman who presented with dysphagia and weight loss.Endoscopy and imaging revealed a T4N1M0 cervical esophageal squamous cell carcinoma.He received image-guided intensity-modulated radiation therapy,with concurrent weekly carboplatin(area under curve 2 mg/mL per minute)and paclitaxel(50 mg/m2 of body surface area).One week after treatment initiation(16.2 Gy thus far),he developed cough on swallowing.A TEF was detected on image-guided radiation therapy using cone-beam computed tomography during the treatment course,for which a tracheal stent was inserted.After discussing the risks and morbidity of continuing treatment,he resumed chemoradiotherapy with an additional radiation dose of 45 Gy in 25 fractions.Three months after completion of chemoradiotherapy,he developed an esophageal stricture that required esophageal stenting and dilatation.The patient remains cancer-free at two year on follow-up.Complete response of esophageal cancer was evident on post-treatment endoscopy and computed tomography imaging,with successful closure of TEF.CONCLUSION This case highlights that successful curative treatment for esophageal cancer complicated by a TEF is possible using novel chemotherapeutic regimens and modern radiation technologies. | Chia Ching Lee Chong Ming Yeo Wee Khoon Ng Akash Verma Jeremy CS Tey | 2020 | World Journal of Clinical Cases2020，8，10： | 2 |
| 2 | Imaging and staging of transitional cell carcinoma:part 2,upper urinary tract显示文摘 | Vikram R Sandier CM Ng CS | 2009 | AJR2009，192，6： | 1 |
| 3 | On-site sorting of construction and demolition waste in Hong Kong 显示文摘 | Poon CS Ann TW Yu Ng LH | 2001 | Resources Conservation and Recycling2001，32，1： | 1 |
| 4 | Antifungal susceptibility of eandida albicans biofilms on titanium discs with different surface roughness显示文摘 | TSANG CS NG H MCMILLAN AS | 2007 | Clin Oral Investig2007，11，4： | 1 |
| 5 | NRAS mutation status is an independent prognostic factor in metastatic melanoma 显示文摘 | Jakob JA Bassett RL Ng CS | 2012 | Cancer2012，118，16： | 1 |
| 6 | Antifungal susceptibility of Candida albicans biofilms on titanium discs with different surface roughness显示文摘 | Tsang CS Ng H McMil an AS | | 0，，04： | 1 |
| 7 | Tranperitoneal versus retroperitoneal lapsroscopic partial nephrectomy:patient selection and peripoerative out- comes显示文摘 | Ng CS Gill IS Ramani AP | 2005 | J Urol2005，174，3： | 1 |
| 8 | Transpcritoncal versus retroper- itoneal laparoseopic partial nephrectomy:patient selection and peri- operative outcomes显示文摘 | Ng CS Gill IS Ramani AP | 2005 | J Uro12005，174，3： | 1 |
| 9 | Video-assisted thoracic surgery for early stage lung cancer-can short-term immunological advanta- ges improve long-term survival? 显示文摘 | Ng CS Wan S Hui CW | 2006 | Annals of thoracic and cardio- vascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia2006，12，5： | 1 |
| 10 | Imaging of neuroendocrine tumors显示文摘 | Tamm EP Kim EE Ng CS | 2007 | He- matol Oncol Clin North Am2007，21，3： | 1 |
| 11 | Subcutaneous panniculitis-like T-cell lymphoma:an elusive case presenting as lipomembranous panniculitis and a review of 72 cases in the literature显示文摘 | Weenig RH Ng CS Perniciaro C | 2001 | Am J Dermatopathol2001，23，3： | 1 |
| 12 | Mitral valve repair: past, present, and future显示文摘 | Wong RH Lee AP Ng CS | 2010 | Asian Cardiovasc Thorac Ann2010，18，6： | 1 |
| 13 | Pulmonary ischaemia-reper- fusion injury: role of apoptosis 显示文摘 | Ng CS Wan S Yim AP | 2005 | Eur Respir J2005，25，2： | 1 |
| 14 | Discordance CD3 expression in lymphomas when studied on frozen and paraffin sections显示文摘 | Chan JKC Tsang WYW Ng CS | 1995 | Hum Pathol1995，26，10： | 1 |
| 15 | Spontaneous haemopneumo- thorax: current management 显示文摘 | Ng CS Wong RH Wan IY | 2011 | Postgrad Med J2011，87，1031： | 1 |
| 16 | Video assisted thoracic surgery in the management of spontaneous pneumothorax : the current status 显示文摘 | Ng CS Lee TW Wan S | 2006 | Postgrad Med J2006，82，965： | 1 |
| 17 | Pulmonary dysfunction after cardiac surgery显示文摘 | Ng CS Wan S Yin AP | 2002 | Chest2002，121，： | 1 |
| 18 | Video-assisted thoracic surgery for primary spontaneous hemopneumothorax 显示文摘 | Hwong TM Ng CS Lee TW | 2004 | Eur J Cardiothorac Surg2004，26，5： | 1 |
| 19 | Laparoscopic management of caliceal diverticular calculi显示文摘 | Miller SD Ng CS Streem SB | 2002 | J Urol2002，167，3： | 1 |
| 20 | Imaging and staging of transitional cell carcinoma: part 2, upper urinary tract显示文摘 | Vikram R Sandier CM Ng CS | 2009 | American Joumal of Roentgenology2009，192，6： | 1 |
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