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| 1 | 影响三地居民黄曲霉毒素B_1-白蛋白加合物的相关因素分析显示文摘[目的]分析影响存在肝癌发病率梯度的三地居民个体黄曲霉毒素生物效应的相关因素。[方法]对广西扶挼两个自然村农民、南宁和四川成都城市居民采用酶联免疫法检测血浆黄曲霉毒素B1-白蛋白加合物(AFB1-AlbuminAdducts,AAA)水平、肝炎病毒(hepatitisvirus,HV)标志物(HBV两对半,HCV、HDV、HEV和HGV抗体)及肝功能。[结果]扶挼47.2%(42/89)的居民至少1种HV感染标志物阳性;南宁和成都分别为15.8%(31/196)和22.7%(27/119)。Log(AAA)水平(n,x±s)为扶挼(89,2.44±0.16)和南宁(196,2.45±0.15)均高于成都(118,2.20±0.24),(P=0.000);但扶挼与南宁间差别无显著性(P=0.859)。南宁(P=0.023)、成都(P=0.026)两地男性AAA水平均高于女性。扶挼和成都两地HV感染者AAA水平均高于非感染者(P分别为0.447和0.041)。HV(-)组中,AAA水平与年龄(r=-0.199,P=0.000)和BMI(r=-0.158,P=0.006)负相关。HV(+)组AAA分别与白蛋白(P=0.000)、球蛋白(P=0.012)和天冬氨酸转氨酶(P=0.052)相关,而HV(-)组AAA分别与直接胆红素、间接胆红素、白蛋白、γ-谷氨酰转肽酶、总胆汁酸和碱性磷酸酶相关(P<0.05)。[结论]AFB1暴露的生物效应可能受肝炎病毒感染、性别、年龄和代谢等因素的影响。AAA与肝功能指标的相关性提示AFB1对肝脏实质或胆道细胞的损害作用。 | 彭涛 刘志明 刘唐威 黎乐群 秦雪 彭民浩 李佳荃 严律南 梁任祥 韦忠亮 Han-Ming Shen Ong Choon Nam LianWen Wang Qiao Wang Regina M Santella | 2005 | 环境与职业医学2005，22，3： | 3 |
| 2 | Outcomes of Roux-en-Y gastric bypass and laparoscopic adjustable gastric banding显示文摘AIM:To evaluate weight loss and surgical outcomes of Roux-en-Y gastric bypass(RYGB)and laparoscopic adjustable gastric band(LAGB).METHODS:Data relating to changes in body mass index(BMI)and procedural complications after RYGB(1995-2009;n=609;116M:493F;42.4±0.4 years)or LAGB(2004-2009;n=686;131M:555F;37.2±0.4years)were extracted from prospective databases.RESULTS:Pre-operative BMI was higher in RYGB than LAGB patients(46.8±7.1 kg/m2vs 40.4±4.2 kg/m2,P<001);more patients with BMI<35 kg/m2underwent LAGB than RYGB(17.1%vs 4.1%,P<0.0001).BMI decrease was greater after RYGB.There were direct relationships between weight loss and pre-operative BMI(P<0.001).Although there was no difference in weight loss between genders during the first 3-year post-surgery,male LAGB patients had greater BMI reduction than females(-8.2±4.3 kg/m2vs-3.9±1.9kg/m2,P=0.02).Peri-operative complications occurred more frequently following RYGB than LAGB(8.0%vs0.5%,P<0.001);majority related to wound infection.LAGB had more long-term complications requiring corrective procedures than RYGB(8.9%vs 2.1%,P<0.001).Conversion to RYGB resulted in greater BMI reduction(-9.5±3.8 kg/m2)compared to removal and replacement of the band(-6.0±3.0 kg/m2).Twelve months post-surgery,fasting glucose,total cholesterol and low density lipoprotein levels were significantly lower with the magnitude of reduction greater in RYGB patients.CONCLUSION:RYGB produces substantially greater weight loss than LAGB.Whilst peri-operative complications are greater after RYGB,long-term complication rate is higher following LAGB. | Nam Q Nguyen Philip Game Justin Bessell Tamara L Debreceni Melissa Neo Carly M Burgstad Pennie Taylor Gary A Wittert | 2013 | World Journal of Gastroenterology2013，19，36： | 3 |
| 3 | Effect of InterlamellarSpacing on Cementite Dissolution during Wire Drawing ofPearlitic Steel Wires 显示文摘 | Nam W J Bae C M Oh S J | 2000 | Scripta Mater2000，42，： | 2 |
| 4 | Relationship between organic matter content of soil and the sequestration of phenanthrene显示文摘 | Nam K Chung N Alexander M | 1998 | Environ Sci Technol1998，32，23： | 1 |
| 5 | The study of seepage forces acting on the tunnel lining and tunnel face in shallow tunnels显示文摘 | Lee I M Nam S W | 2001 | Tunneling and Underground Space Technology2001，16，： | 1 |
| 6 | Flavone glycosides from Mentha longifolia显示文摘 | Sharaf M El-Ansari MA Saleh NAM | 1999 | Fitoterapia1999，70，6： | 1 |
| 7 | Prevention of lipid radiolysis by natural antioxidants from rosemary and thyme 显示文摘 | Lacroix M Smoragiewicz W Nam K C | 1997 | Food Research International1997，30，6： | 1 |
| 8 | Strain rate dependence of deformation behavior of high-nitrogen austenitic steels显示文摘 | KIM Y S NAM S M KIM S J | 2007 | Journal of Materials Processing Technology2007，，： | 1 |
| 9 | Effect of interlamellar spacing on cementite dissolution during wire drawing of pearlitic steel wires显示文摘 | Nam W J Bae C M Oh S J | 2000 | Scripta Mater2000，42，5： | 1 |
| 10 | Nucleation and growth behavior of chromium nitride film deposited on various substrates by magnetron sputtering显示文摘 | Jung M J Nam K H Jung Y M | 2003 | Surface and Coatings Technology2003，171，： | 1 |
| 11 | The mitochondrial death pathway and cardiac myocyte apoptosis显示文摘 | CROW M T MANI K NAM Y J | 2004 | Circ Res2004，95，10： | 1 |
| 12 | Decomposition of volatile organic compounds and nitric oxide by non thermal plasma discharge process显示文摘 | Mok Y S Nam C M Cho M H | 2002 | IEEE Transaction on Plasma Science2002，30，1： | 1 |
| 13 | Multiresolution edge detection techniques显示文摘 | Park D J Nam K M Park R H | 1995 | Pattern Recognition1995，28，2： | 1 |
| 14 | Electro - magnetic Design of a Magneto - theological Damper 显示文摘 | NAM Y J PARK M K | 2009 | Journal of Intelligent Material Sys- tems and Structures2009，20，2： | 1 |
| 15 | Role of nanoporosity and hydrophobicity in sequestration and bioavailability: Tests with model solids 显示文摘 | Nam K Alexander M | 1998 | Environmental Science & Technology1998，32，1： | 1 |
| 16 | Use of egg yolk-derived immunoglobulin as an alternative to antibiotic treatment for control of Helicobacter pylori infection显示文摘 | Shin JH Yang M Nam SW | 2002 | Clin Diagn Lab Immunol2002，9，5： | 1 |
| 17 | Foam Processing and Cellular Structure of Polypropylene/Clay Nanocom- posites 显示文摘 | Nam P H Maiti P Okamoto M | 2002 | Polymer Engineering and Science2002，42，9： | 1 |
| 18 | Growth suppression of preT acute lymphoblastic leukemia cells by inhibition of notch signaling显示文摘 | Weng A P Nam Y Wolfe M S | 2003 | Mol Cell Biol2003，23，2： | 1 |
| 19 | A parametric approach for initial hull form modeling using NURBS representation 显示文摘 | NAM J H PARSONS M G | 2000 | J Ship Prod2000，16，24： | 1 |
| 20 | Fusion of multispectral and panchromatic satellite images using the curvelet trans- form显示文摘 | CHOU M KIM R Y NAM M | 2005 | IEEE Geoscience and RemoteSensing Letters2005，2，2： | 1 |
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