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| 1 | Portal vein thrombosis and arterioportal shunts:Effects on tumor response after chemoembolization of hepatocellular carcinoma显示文摘AIM: To evaluate the effect of portal vein thrombosis and arterioportal shunts on local tumor response in advanced cases of unresectable hepatocellular carcinoma treated by transarterial chemoembolization. METHODS: A retrospective study included 39 patients (mean age: 66.4 years, range: 45-79 years, SD: 7) with unresectable hepatocellular carcinoma (HCC) who were treated with repetitive transarterial chemoembolization (TACE) in the period between March 2006 and October 2009. The effect of portal vein thrombosis (PVT) (in 19 out of 39 patients), the presence of arterioportal shunt (APS) (in 7 out of 39), the underlying liver pathology,Child-Pugh score, initial tumor volume, number of tumors and tumor margin definition on imaging were correlated with the local tumor response after TACE. The initial and end therapy local tumor responses were evaluated according to the response evaluation criteria in solid tumors (RECIST) and magnetic resonance imaging volumetric measurements. RESULTS: The treatment protocols were well tolerated by all patients with no major complications. Local tumor response for all patients according to RECIST criteria were partial response in one patient (2.6%), stable disease in 34 patients (87.1%), and progressive disease in 4 patients (10.2%). The MR volumetric measurements showed that the PVT, APS, underlying liver pathology and tumor margin definition were statistically significant prognostic factors for the local tumor response (P = 0.018, P = 0.008, P = 0.034 and P = 0.001, respectively). The overall 6-, 12- and 18-mo survival rates from the initial TACE were 79.5%, 37.5% and 21%, respectively. CONCLUSION: TACE may be exploited safely for palliative tumor control in patients with advanced unresectable HCC; however, tumor response is significantly affected by the presence or absence of PVT and APS. | Thomas J Vogl Nour-Eldin Nour-Eldin Sally Emad-Eldin Nagy NN Naguib Joerg Trojan Hans Ackermann Omar Abdelaziz | 2011 | World Journal of Gastroenterology2011，17，10： | 20 |
| 2 | Trans-arterial chemoperfusion for the treatment of liver metastases of breast cancer and colorectal cancer: Clinical results in palliative care patients显示文摘AIM To evaluate the clinical value and efficiency of transarterial chemoperfusion(TACP) in patients with liver metastases from breast cancer(BC) and colorectal cancer(CRC).METHODS We treated 36 patients with liver metastases of BC(n = 19, 19 females) and CRC(n = 17; 8 females, 9 males) with repeated TACP. The treatment interval was 4 wk. TACP was performed with gemcitabine(1000 mg/m2) and mitomycin(10 mg/m2), administered within 1 h after positioning the catheter tip in the hepatic artery. Before treatment, the size, location, tumour volume, vascularization and number of liver tumours were evaluated using magnetic resonance imaging(MRI). Tumour response was evaluated according to the Response Evaluation Criteria in Solid Tumors guidelines.RESULTS TACP using gemcitabine and mitomycin for metastases from CRC and BC was performed without any serious side effects. The follow-up MRI showed a therapeutic response in 84.2% of the BC patients-stable disease 47.4% and partial response 36.8%. A progression was seen in 15.8%.CRC patients showed a therapeutic response in 52.9% of cases. A progression of the disease was documented in 47.1% of the patients with CRC. These data show that TACP in patients with liver metastases of BC leads to a significantly better therapeutic response compared with CRC patients(P = 0.042). The median survival time was 13.2 mo for the BC patients, which is significantly longer than for CRC patients at 9.3 mo(P = 0.001).CONCLUSION TACP for liver metastases of BC appears to be a safe and effective palliative treatment with improved outcomes in comparison to patients with CRC. | Tatjana Gruber-Rouh Marcel Langenbach Nagy NN Naguib Nour-Eldin M Nour-Eldin Thomas J Vogl Stephan Zangos Martin Beeres | 2017 | World Journal of Clinical Oncology2017，8，4： | 7 |
| 3 | The Transforming Growth Factor-β Superfamily Member Growth-Differentiation Factor-15 Protects the Heart From Ischemia/Reperfusion Injury显示文摘 | Tibor Kempf Matthias Eden Jens Strelau Marian Naguib Christian Willenbockel J?rn Tongers J?rg Heineke Daniel Kotlarz Jian Xu Jeffery D. Molkentin Hans W. Niessen Helmut Drexler Kai C. Wollert | 2006 | Circulation Research2006，，3： | 3 |
| 4 | Challenge to forty-fold expansion of biodegradable polyester foams using CO2 显示文摘 | Park C B Liu Y Naguib H E | 1999 | Cellular Polymers1999，18，6： | 2 |
| 5 | Adaptive Fuzzy Sliding Mode Power System Stabilizer Using Nussbaum Gain显示文摘Power system stability is enhanced through a novel stabilizer developed around an adaptive fuzzy sliding mode approach which applies the Nussbaum gain to a nonlinear model of a single-machine infinite-bus (SMIB) and multi-machine power system stabilizer subjected to a three phase fault. The Nussbaum gain is used to avoid the positive sign constraint and the problem of controllability of the system. A comparative simulation study is presented to evaluate the achieved performance. | Emira Nechadi Mohamed Naguib Harmas Najib Essounbouli Abdelaziz Hamzaoui | 2013 | International Journal of Automation and computing2013，10，4： | 2 |
| 6 | Towards hepatitis C virus elimination:Egyptian experience,achievements and limitations显示文摘Worldwide, more than one million people die each year from hepatitis C virus(HCV) related diseases, and over 300 million people are chronically infected with hepatitis B or C. Egypt used to be on the top of the countries with heavy HCV burden. Some countries are making advances in elimination of HCV, yet multiple factors preventing progress; remain for the majority. These factors include lack of global funding sources for treatment, late diagnosis, poor data, and inadequate screening. Treatment of HCV in Egypt has become one of the top national priorities since 2007. Egypt started a national treatment program intending to provide cure for Egyptian HCV-infected patients. Mass HCV treatment program had started using Pegylated interferon and ribavirin between 2007 and 2014. Yet, with the development of highly-effective direct acting antivirals(DAAs) for HCV, elimination of viral hepatitis has become a real possibility. The Egyptian National Committee for the Control of Viral Hepatitis did its best to provide Egyptian HCV patients with DAAs. Egypt adopted a strategy that represents a model of care that could help other countries with high HCV prevalence rate in their battle against HCV. This review covers the effects of HCV management in Egyptian real life settings and the outcome of different treatment protocols. Also, it deals with the current and future strategies for HCV prevention and screening as well as the challenges facing HCV elimination and the prospect of future eradication of HCV. | Dalia Omran Mohamed Alboraie Rania A Zayed Mohamed-Naguib Wifi Mervat Naguib Mohamed Eltabbakh Mohamed Abdellah Ahmed Fouad Sherief Sahar Maklad Heba Hamdy Eldemellawy Omar Khalid Saad Doaa Mohamed Khamiss Mohamed El Kassas | 2018 | World Journal of Gastroenterology2018，24，38： | 2 |
| 7 | Effect of Recycling on the Rheological Properties and Foaming Behaviors of Branched Polypropylene显示文摘 | Naguib H E Wang J Park C B | 2003 | Cellular Polymers2003，22，1： | 1 |
| 8 | A space-time coding modem for high-data-rate wireless communications显示文摘 | Naguib A F Tarokh V Seshadri N | 1998 | IEEE Journal on Selected Areas in Communications1998，16，8： | 1 |
| 9 | A study on the foaming behaviors of PP resins with talc as nucleating agent显示文摘 | Naguib H E Park G B Lee P C | 2006 | J Polym Eng2006，26，6： | 1 |
| 10 | Predictive performance of three multivariate difficult tracheal intubation models:a double-blind,case-controlled study显示文摘 | Naguib M Scamman FL O'Sullivan C | 2006 | Anesth Analg2006，102，3： | 1 |
| 11 | Propofol: the challenges of formulation 显示文摘 | Baker MT Naguib M | 2005 | Anesthesiology2005，103，4： | 1 |
| 12 | Dexmedetomidine: applications for the pediatric patient with congenital heart disease 显示文摘 | TOBIAS J D GUPTA P NAGUIB A | 2011 | PediatrCardiol2011，32，8： | 1 |
| 13 | Leiomyoma vol- ume changes at follow-up after uterine artery embolization : corre- lation with the initial leiomyoma volume and location 显示文摘 | Naguib NN Mbalisike E Nour-Eldin NE | 2010 | J Vasc Interv Radio12010，21，4： | 1 |
| 14 | Prevention of Paclitaxel-induced neuropathy through activation of the central cannabinoid type 2 receptor system显示文摘 | Naguib M Xu J J Diaz P | 2012 | Anesth Analg2012，114，5： | 1 |
| 15 | Combined Array Processingand Space - Time Coding 显示文摘 | TAROKH V NAGUIB A SESHADRI N | 1999 | IEEE Trans on Information Theory1999，45，4： | 1 |
| 16 | Space- time coding and signal processing for high date rate wireless communications 显示文摘 | Naguib A F Calderbank R | 2000 | IEEE Signal Processing Magazine2000，17，3： | 1 |
| 17 | The effects of mela-tonin premedication on propofol and thiopental induction dose-re-sponse curves: a pospective, randomized, double blind study显示文摘 | Naguib M Samarkandi AH Moniem MA | 2006 | Anesth Analg2006，103，： | 1 |
| 18 | A space-time coding modem for high-data-rate wireless communications显示文摘 | Naguib A F Vahid T Seshadri N | 1998 | IEEE Journal on Selected Areas in Communications1998，16，8： | 1 |
| 19 | Adverse effects and drug interactions associated with local and regional anaesthesia显示文摘 | Naguib M Magboul MM Samarkandi AH | | 0，，04： | 1 |
| 20 | Chitosan Based Nanofibers, Review 显示文摘 | Elsabee M Z Naguib H F Morsi R E | 2012 | Materials Science and Engineering: C2012，32，7： | 1 |
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