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13篇 您的检索式:作者名="Mutapi"
    题名 作者 年代 出处 被引量
1Human Schistosome Infection and Allergic Sensitisation显示文摘Nadine Rujeni David W. Taylor Francisca Mutapi Maria Ilma Araujo 2012Journal of Parasitology Research2012,,:1
2Differential recognition pat- terns of Sehistosoma haematobium adult worm antigens by the human antibodies IgA,IgE,IgG1 and IgG4显示文摘Mutapi F Bourke C Harcus Y 2011Parasite Immunol2011,33,3:1
3Infection and treatment immunizations for successful parasite vaccines显示文摘Mutapi F Billingsley P F Secor W E 2013Trends in Parasitology2013,29,3:1
4Cluster analysis of schistosome-specific antibody responses artitions the population into distinct epidemiological groups 显示文摘MUTAPI F MDULUZA T RODDAM A W 2005Immunology Letters2005,96,2:1
5Praziquantel treatment of individuals'exposed to Schistosoma haematobium enhances serological recognition of defined parasite antigens显示文摘Mutapi F Burchmore R Mduluza T 2005J Infect Dis2005,192,6:1
6Putting the treatment of paediatric schistosomiasis into context显示文摘Despite increased international efforts to control schistosomiasis using preventive chemotherapy,several challenges still exist in reaching the target populations.Until recently,preschool-aged children had been excluded from the recommended target population for mass drug administration,i.e.primary school children aged 6-15 years.Our studies and those of others provided the evidence base for the need to treat preschool-aged children that led to recommendations by the World Health Organization to include preschool-aged children in treatment programmes in 2010.The major challenge now lies in the unavailability of a child-size formulation of the appropriate anthelmintic drug,praziquantel.The currently available formulation of praziquantel presents several problems.First,it is a large tablet,making it difficult for young children and infants to swallow it and thus requires its breaking/crushing to allow for safe uptake.Second,it is bitter so it is often mixed with a sweetener to make it palatable for young children.Third,the current formulation of 600 mg does not allow for flexible dose adjustments for this age group.Thus,there is a need to formulate a child-appropriate praziquantel tablet.This paper discusses the target product profile for paediatric praziquantel,as well as knowledge gaps pertinent to the successful control of schistosome infection and disease in preschool-aged children.Takafira Mduluza Francisca Mutapi 2017Infectious Diseases of Poverty2017,6,1:1
7Differential recognition patterns of Schistosoma haematobium adult worm antigens by the human antibodies IgA, IgE, IgG1 and IgG4显示文摘Mutapi F Bourke C Harcus Y 2011Parasite Immunol2011,33,3:1
8A comparison of humoral re- sponses to schistosomiasis haematobium in areas with low and high levels of infection显示文摘Mutapi F Ndhlovu P Hagan P 1997Parasite Immunol1997,19,3:1
9Praziquantel treatment of individuals exposed to Schistosoma haematobium enhances serological recognition of defined parasite antigens 显示文摘Mutapi F Burchmore R Mduluza T 2005J Infect Dis2005,192,6:1
10Chemotherapy-induced, age-related changes in antischistosome antibody responses显示文摘Mutapi F Hagan P Woolhouse ME 2003Parasit Immunol2003,25,:1
11Chemotherapy-induced, age-related changes in antischistosome antibody responses显示文摘Mutapi F Hagan P Woolhouse ME 2003Parasit Immunol2003,25,:1
12Sehistosome infection inten- sity is inversely related to auto-reactive antibody levels显示文摘Mutapi F Imai N Nansch N 2011PLoS One2011,6,19:1
13Similar cellular respon- ses after treatment with either praziquantel or oxamniquine in Schistosoma mansoni infection 显示文摘Mduluza T Mutapi F Ruwona T 2009Malawi Med J2009,21,4:1
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