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| 1 | Mitochondrial H2O2 generated from electron transport chain complex I stimulates muscle differentiation显示文摘Mitochondrial 反应的氧种类(mROS ) 被认为有害到房间。然而,他们的生理的角色一直不作为表明调停人是彻底地探索了。这里,我们调查了 mROS 是否从 mitochondrial 电子运输链(mETC ) 产生了复杂我刺激了肌肉区别。我们的结果证明 mROS 的数量被增加并且锰 superoxide dismutase (MnSOD ) 在肌肉区别期间经由 NF-B 激活被导致。指向线粒体的抗氧化剂(MitoQ 和 MitoTEMPOL ) 和指向线粒体的过氧化氢酶减少了没有影响 ATP 的数量的 mROS 数量和压制的肌肉区别。Mitochondrial 改变包括在线粒体的数字和尺寸的 mitochondrial 抄写因素 A 和增加的正式就职,并且功能的激活在肌肉区别期间被观察。特别地,增加了 mETC 建筑群的表示层次我子单元和建筑群的一项更高的活动我比另外的建筑群被观察。毒鱼藤素, mETC 建筑群的一个禁止者我,减少 mitochondrial NADH/NAD+ 比率和 mROS 层次在肌肉区别期间。mROS 铺平的我用小介入 RNA 和毒鱼藤素减少了的建筑群的抑制,压制的肌肉区别,和有伴随物的弄空的 ATP 层次在 glycolysis 增加。从这些结果,我们结束那复杂我导出 | Seonmin Lee Eunyoung Tak Jisun Lee MA Rashid Michael P Murphy Joohun Ha Sung Soo Kim | 2011 | Cell Research2011，21，5： | 4 |
| 2 | A reduction in serum cytokine levels parallels healing of venous ulcers in patients under2going compression therapy显示文摘 | Murphy HA Joyce WP Condson C | 2002 | Eur Vase Endovasc Surg2002，23，： | 1 |
| 3 | Relative importance of immune and non-immune causes of platelet refractoriness显示文摘 | Doughty HA Murphy MF Metcalfe P | 1994 | Vox Sang1994，66，3： | 1 |
| 4 | Risk factors, treatment, and outcome of central nervous system recurrence in adults with intermediate-grade and immunoblastic lymphoma 显示文摘 | Besien K V Ha C S Murphy S | 1998 | Blood1998，91，4： | 1 |
| 5 | Use of nitrous oxide and oxygen for conscious sedation to manage pain and anxiety 显示文摘 | Ryding HA Murphy HJ | 2007 | J Can Dent Assoc2007，73，8： | 1 |
| 6 | Relative importence of immune and norimmune cause of platelet refractoriness显示文摘 | Doughty HA Murphy MF Metcalfe P | 1994 | Vox Sang1994，66，2： | 1 |
| 7 | Use of nitrous oxide and oxygen forconscious sedation to manage pain and anxiety显示文摘 | Ryding HA Murphy HJ | 2007 | J CanDentAssoc2007，73，8： | 1 |
| 8 | Risk factors, treat- ment, and outcome of central nervous system recurrence in adults with intermediate grade and immunoblastic lymphoma 显示文摘 | Van Besien K Ha CS Murphy S | 1998 | Blood1998，91，4： | 1 |
| 9 | Probing single-stran-ded DNA conformational flexibility using fluorescencespectroscopy 显示文摘 | Murphy M C Rasnik I Ha T | 2004 | Biophysical Journal2004，86，： | 1 |
| 10 | Relative importence of immune and norimmune cause of platelet refractoriness显示文摘 | Doughty HA Murphy MF Metcalfe P | 1994 | Vox Sang1994，66，2： | 1 |
| 11 | Update on atten- tion-deficit/hyperactivity disorder and tic disorders:a review of the current literature显示文摘 | Simpson HA Jung L Murphy TK | 2011 | Curr Psychiatry Rep2011，13，5： | 1 |
| 12 | Increased corticotropin- releasing hormone immunoreactivity in g pontine nuclei of depressed suicide men 显示文摘 | Austin MC Janosky JE Murphy HA | 2003 | Mol Psychiatry2003，8，3： | 1 |
| 13 | Laparoscopic versus open pyeloplasty in children: preliminary report of a prospective randomized trial 显示文摘 | Penn HA Gatti JM Murphy JP | 2010 | J Urol2010，184，2： | 1 |
| 14 | Ocular rosacea in childhood显示文摘 | Nazir HA Murphy S Siatkowski RM ct al | 2004 | Am J Ophthalmol2004，137，： | 1 |
| 15 | Use of nitrous oxide and oxygen for conscious sedation to manage pain and anxiety 显示文摘 | Ryding HA Murphy HJ | 2007 | J Can Dent Assoc2007，73，8： | 1 |
| 16 | Use of nitrous oxide and oxygen for conscious sedation to manage pain and anxiety显示文摘 | Ryding HA Murphy HJ | 2007 | J Can Dent Assoe2007，73，8： | 1 |
| 17 | Results of treatment with hyper-CVAD,a dose-intensive regimen,in adult acute lymphocytic leukemia显示文摘 | Kantarjian HM O'Brien S Smith TL Cortes J Giles FJ Beran M Pierce S Huh Y Andreeff M Koller C Ha CS Keating MJ Murphy S Freireich EJ | 2000 | J Clin Oncol2000，18，3： | 1 |
| 18 | Dermalabsorption of a liquid diphacinone rodenticide causingcoagulaopathy显示文摘 | Spiller HA Gallenstein GL Murphy MJ | 2003 | Vet Human Toxicol2003，45，6： | 1 |
| 19 | Assessing outcomes of curricular ch- ange:a view from program graduates显示文摘 | RYDING HA MURPHY HJ | 2001 | J Dent Educ2001，65，5： | 1 |
| 20 | Use of nitrous oxide and oxygen for conscious sedation to manage pain and anxiety 显示文摘 | Ryding HA Murphy HJ | 2007 | J Can Dent Assoc2007，73，8： | 1 |
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