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| 1 | Aqueous suspension of anise “Pimpinella anisum” protects rats against chemically induced gastric ulcers显示文摘AIM: To substantiate the claims of Unani and Arabian traditional medicine practitioners on the gastroprotective potential effect of a popular spice anise, 'Pimpinella anisum L.' on experimentally-induced gastric ulceration and secretion in rats. METHODS: Acute gastric ulceration in rats was produced by various noxious chemicals including 80% ethanol, 0.2 mol/L NaOH, 25% NaCl and indomethacin. Anti-secretory studies were undertaken using pylorus- ligated Shay rat technique. Levels of gastric non-protein sulfhydryls (NP-SH) and wall mucus were estimated and gastric tissue was also examined histologically. Anise aqueous suspension was used in two doses (250 and 500 mg/kg body weight) in all experiments. RESULTS: Anise significantly inhibited gastric mu- cosal damage induced by necrotizing agents and indomethacin. The anti-ulcer effect was further confirmed histologically. In pylorus-ligated Shay rats, anise suspension significantly reduced the basal gastric acid secretion, acidity and completely inhibited the rumenal ulceration. On the other hand, the suspension significantly replenished ethanol-induced depleted levels of gastric mucosal NP-SH and gastric wall mucus concentration. CONCLUSION: Anise aqueous suspension possesses significant cytoprotective and anti-ulcer activities against experimentally-induced gastric lesions. The anti-ulcer effect of anise is possibly prostaglandin-mediated and/orthrough its anti-secretory and antioxidative properties. | Ibrahim A Al Mofleh Abdulqader A Alhaider Jaber S Mossa Mohammed O Al-Soohaibani Syed Rafatullah | 2007 | World Journal of Gastroenterology2007，13，7： | 7 |
| 2 | Dyeing of cotton in supercritical carbon dioxide显示文摘 | Beltrame P L Castelli A Selli E Mossa A Testa G Bonfatti A M and Seves A | 1998 | Dyes and Pigments1998，39，： | 1 |
| 3 | Comparison of different commercially available cationic liposome-DNA lipoplexes: parameters influencing toxicity and transfection efficiency显示文摘 | Masotti A Mossa G Cametti C | 2009 | Colloids SurfB Biointerfaces2009，68，2： | 1 |
| 4 | The worldwide air transportation network: Anomalous centrality, community structure, and cities' global roles显示文摘 | Guimera R Mossa S Turtschi A | 2005 | Proceedings of the National Academy of Sciences of the United States of America2005，102，22： | 1 |
| 5 | Application of nuclear magnetic resonance spectroscopy for quantitative analysis of miconazole, metronidazole and sulfamethoxazole in pharmaceutical and urine samples 显示文摘 | Salem A A Mossa H A Barsoum B N | 2006 | J Pharm Biomed Anal2006，41，2： | 1 |
| 6 | The world-wide air transportation network: Anomalous central- ity, community structure, and cities global roles显示文摘 | Guimer'a R Mossa S Turtschi A | 2005 | Proceedings of the National Academy of Sciences2005，102，22： | 1 |
| 7 | The worldwide air transportation network:anomalous centrality,community structure,and cities' global roles显示文摘 | Guimera R Mossa S Turtschi A | 2005 | PNAS2005，102，22： | 1 |
| 8 | The world-wide air transporation network: anomalous centrality,communitystructure, and cities' global roles显示文摘 | Guimera R Mossa S Turtschi A | 2005 | Proceeding of the National Academy Science2005，102，77： | 1 |
| 9 | The worldwide air transportation network : Anomalous centrality, community structure, and cities global roles 显示文摘 | Guimere R Mossa S Turtschi A | 2005 | PNAS2005，102，22： | 1 |
| 10 | Ovarian cysts during pregnancy dilemmas in diagnosis and management显示文摘 | EI-Shawarby S A Henderson A F Mossa M A | 2005 | J Obstet Gynecol2005，25，7： | 1 |
| 11 | Experimental studies on antirheu- matic drugs used in Saudi traditional medicine显示文摘 | Ageel A Mossa J al-Yahya M | 1989 | Drugs under Experiment Clin Res1989，15，： | 1 |
| 12 | The worldwide air transportation network:anomalous centrality,community structure,and cities , global roles 显示文摘 | Guimera R Mossa S Turtschi A Amaral LAN | 2005 | PNAS2005，102，22： | 1 |
| 13 | The worldwide air transportation network: Anomalous centrality, community structure, and cities' global roles显示文摘 | R Guimera S Mossa A Turtschi L A N Amaral | 2001 | Proc Nati Acad Sci USA2001，102，2： | 1 |
| 14 | Persistent infection of human vascular endothelial cells by group B coxsackievirus显示文摘 | Conaldi PG Serra C Mossa A | 1997 | J Infect Dis1997，175，3： | 1 |
| 15 | The world-wide air transportation network: anomalous centrality, community structure, and cities' global roles 显示文摘 | Guimera R Mossa S Turtschi A | 2005 | Proceedings of the National Academy of Sciences2005，102，22： | 1 |
| 16 | Effects of methomyl on lipid peroxidation and antioxidant enzymes in rat erythrocytes: In vitro studies 显示文摘 | Mansour S A Mossa A T Heikal T M | 2009 | Toxicology and Industrial Health2009，25，8： | 1 |
| 17 | The worldwide air transportation network: anomalous centrality, community structure and cities' global roles显示文摘 | Guimerb R Mossa S Turtschi A | 2005 | Proc Natl Acad Sci USA2005，102，： | 1 |
| 18 | Tailwater level effects on flow conditions at an abrupt drop 显示文摘 | Mossa M PetriUo A Chanson H | 2003 | Journal of Hydraulic Research2003，41，1： | 1 |
| 19 | The worldwide air trans- portation network: anomalous centrality, community structure, and citiescglobal roles 显示文摘 | Guimera R Mossa S Turtschi A | 2005 | Proc NatlAcad SciUSA2005，102，77： | 1 |
| 20 | Multiplexgenotyping of CYP3A4, CYP3AS, CYP2C9 and CYP2C19SNPs usingMALDI-TOF mass spectrometry显示文摘 | Falzoi M Mossa A Congeddu E | 2010 | Pharmacogenomics2010，11，4： | 1 |
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