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| 1 | Aqueous suspension of anise “Pimpinella anisum” protects rats against chemically induced gastric ulcers显示文摘AIM: To substantiate the claims of Unani and Arabian traditional medicine practitioners on the gastroprotective potential effect of a popular spice anise, 'Pimpinella anisum L.' on experimentally-induced gastric ulceration and secretion in rats. METHODS: Acute gastric ulceration in rats was produced by various noxious chemicals including 80% ethanol, 0.2 mol/L NaOH, 25% NaCl and indomethacin. Anti-secretory studies were undertaken using pylorus- ligated Shay rat technique. Levels of gastric non-protein sulfhydryls (NP-SH) and wall mucus were estimated and gastric tissue was also examined histologically. Anise aqueous suspension was used in two doses (250 and 500 mg/kg body weight) in all experiments. RESULTS: Anise significantly inhibited gastric mu- cosal damage induced by necrotizing agents and indomethacin. The anti-ulcer effect was further confirmed histologically. In pylorus-ligated Shay rats, anise suspension significantly reduced the basal gastric acid secretion, acidity and completely inhibited the rumenal ulceration. On the other hand, the suspension significantly replenished ethanol-induced depleted levels of gastric mucosal NP-SH and gastric wall mucus concentration. CONCLUSION: Anise aqueous suspension possesses significant cytoprotective and anti-ulcer activities against experimentally-induced gastric lesions. The anti-ulcer effect of anise is possibly prostaglandin-mediated and/orthrough its anti-secretory and antioxidative properties. | Ibrahim A Al Mofleh Abdulqader A Alhaider Jaber S Mossa Mohammed O Al-Soohaibani Syed Rafatullah | 2007 | World Journal of Gastroenterology2007，13，7： | 7 |
| 2 | Isolation and characterization of two antimicrobial agents from Mace ( nyristica Fragrans ) 显示文摘 | Orabi K Y Mossa J S EI-Feraly F S | 1991 | J Nat Prod1991，54，3： | 1 |
| 3 | The worldwide air transportation network: Anomalous centrality, community structure, and cities' global roles显示文摘 | Guimera R Mossa S Turtschi A | 2005 | Proceedings of the National Academy of Sciences of the United States of America2005，102，22： | 1 |
| 4 | Chaos reduced order anti-synchronization of chaotic systems with fully unknown parameters显示文摘 | Mossa M Al-sawalha Noorani M S M | 2011 | Communications in Nonlinear Science and Numerical Simulation2011，17，4： | 1 |
| 5 | Effect of surface hydrophilicity on the formation of nafion thin films inside PEMFC catalyst layers:A computational study显示文摘 | Borges D D Malek K Mossa S | 2013 | ECS Trans2013，45，23： | 1 |
| 6 | Adaptive anti-Synchronization of two identical and different hyper chaotic systems with uncertain parameters 显示文摘 | MOSSA AL-SAWALHA M NOORANI M S M | 2010 | Communications in Nonlinear Science and Numerical Simulation2010，15，4： | 1 |
| 7 | Protective effect of Swertia chirata against indomethacin and other ulcerogenieagent induced gastric ulcers 显示文摘 | Rafatullah S Tafiq M Mossa J S | 1983 | Drugs Under Eper Clin Res1983，19，2： | 1 |
| 8 | Follow-up in a long-term ran-domized trial with neoadjuvant chemotherapy for squamous cell cer-vical carcinoma 显示文摘 | Mossa B Mossa S Corosu L | 2010 | European journal of gynaecological oncology2010，31，5： | 1 |
| 9 | The world-wide air transportation network: Anomalous central- ity, community structure, and cities global roles显示文摘 | Guimer'a R Mossa S Turtschi A | 2005 | Proceedings of the National Academy of Sciences2005，102，22： | 1 |
| 10 | The worldwide air transportation network:anomalous centrality,community structure,and cities' global roles显示文摘 | Guimera R Mossa S Turtschi A | 2005 | PNAS2005，102，22： | 1 |
| 11 | The world-wide air transporation network: anomalous centrality,communitystructure, and cities' global roles显示文摘 | Guimera R Mossa S Turtschi A | 2005 | Proceeding of the National Academy Science2005，102，77： | 1 |
| 12 | Nitrate reduction by nano-Fe/Cu particles in packed column 显示文摘 | Mossa Hosseini S Ataie-Ashtiani B Kholghi M | 2011 | Desalination2011，276，： | 1 |
| 13 | The worldwide air transportation network : Anomalous centrality, community structure, and cities global roles 显示文摘 | Guimere R Mossa S Turtschi A | 2005 | PNAS2005，102，22： | 1 |
| 14 | Ovarian cysts during pregnancy dilemmas in diagnosis and management显示文摘 | EI-Shawarby S A Henderson A F Mossa M A | 2005 | J Obstet Gynecol2005，25，7： | 1 |
| 15 | The worldwide air transportation network:anomalous centrality,community structure,and cities , global roles 显示文摘 | Guimera R Mossa S Turtschi A Amaral LAN | 2005 | PNAS2005，102，22： | 1 |
| 16 | Adjuvant chemotherapy versus radiation therapy after radical surgery in high - risk positive node stage Ⅰ B/ Ⅱ A cervical cancer显示文摘 | MOSSA B MOSSA S MARZIANI R | 2010 | Eur J Gynaecol Oncol2010，31，5： | 1 |
| 17 | Effects of trehalose co-incu- bation on in vitro matured prepubertal ovine oocyte vitrification 显示文摘 | Berlinguer F Suceu S Mossa F | 2007 | Cryobiology2007，55，： | 1 |
| 18 | The worldwide air transportation network: Anomalous centrality, community structure, and cities' global roles显示文摘 | R Guimera S Mossa A Turtschi L A N Amaral | 2001 | Proc Nati Acad Sci USA2001，102，2： | 1 |
| 19 | A sustainable EOQ model for repairable spare parts under uncertain demand 显示文摘 | Mossa S D Rubino S | 2015 | IMA Journal ofManagement Mathematics2015，26，2： | 1 |
| 20 | The world-wide air transportation network: anomalous centrality, community structure, and cities' global roles 显示文摘 | Guimera R Mossa S Turtschi A | 2005 | Proceedings of the National Academy of Sciences2005，102，22： | 1 |
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