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| 1 | Gender-associated differences in urea breath test for Helicobacter pylori infection referrals and results among dyspeptic patients显示文摘AIM: To verify whether there is a gender difference in the 13C-urea breath test results in a large cohort. METHODS: The test results of dyspeptic patients referred for 13C-urea breath testing between January and December, 2007 were evaluated. Testing was carried out at the health insurance organization branches and evaluated at a central laboratory in Israel. RESULTS: Of a total of 28 746 test results, 18 122 (63.04%) were from females and 10 624 (36.95%) from males. Overall, 10 188 (35.4%) results [expressed as delta over baseline (DOB)] were positive (DOB 13C > 5), 18,326 (63.7%) were negative (DOB 13C < 3.5) and 232 (0.8%) were borderline (DOB 13C 3.5-5). There was a significant difference between the total positive rate among females and males (34.8% vs 37.2%, respectively, P = 0.0003). The mean test value was increased by approximately 10 units for females compared to males (P < 0.01) and this difference was consistent for all age groups (i.e., between 10-80 years of age, P < 0.01). CONCLUSION: More females were referred to 13C-urea breath testing. More males had positive results. The mean test values were significantly higher among females of all age groups, possibly representing an increased bacterial load among females and suggesting gender-associated differences in Helicobacter pylori host interactions. | Menachem Moshkowitz Noya Horowitz Anat Beit-Or Zamir Halpern Erwin Santo | 2012 | World Journal of Gastrointestinal Pathophysiology2012，3，3： | 4 |
| 2 | Gastroesophageal reflux disease symptoms:Prevalence,sociodemographics and treatment patterns in the adult Israeli population显示文摘AIM: To evaluate the prevalence and sociodemographics of gastroesophageal reflux disease (GERD) symptoms and to identify treatment patterns among GERD patients. METHODS: A telephone survey of a representative sample of the adult Israeli population was conducted. The questionnaire included detailed sociodemographics, history of GERD symptoms and the various treatments used. RESULTS: The survey included 2027 subjects. Twice weekly, once weekly and monthly GERD symptoms were reported by 8.4%, 12.5% and 21.5% of subjects, respectively. There was no difference in prevalence between men and woman; however, GERD symptoms were significantly more prevalent within the older age group and lower socioeconomic status. Among those reporting weekly symptoms, a quarter did not use any kind of therapy and another quarter used various traditional remedies (e.g. soda, milk, almonds, etc.). Antacids were used by 35.1%, H2 blockers by 13.2% and PPIs by 17.5%. CONCLUSION: We found that 12.5% of the adult Israeli population experience weekly GERD symptoms. GERD prevalence and sociodemographics are similar to those described in other Western countries, and treatment is still suboptimal. | Menachem Moshkowitz Noya Horowitz Zamir Halpern Erwin Santo | 2011 | World Journal of Gastroenterology2011，17，10： | 2 |
| 3 | Effect of phoapholiplds and their molecular species on cholesterol solubility and nucleation in huam and model biles显示文摘 | Halpern Z Moshkowitz M Laufer H | 1993 | Gut1993，34，1： | 1 |
| 4 | Halitosis and gastroe-sophageal reflux disease: a possible association 显示文摘 | Moshkowitz M Horowitz N Leshno M | 2007 | Oral Dis2007，13，6： | 1 |
| 5 | Methotrexate in chronic active ulcerative colitis: A double-blind, randomized, Israeli multicenter trial显示文摘 | R Oren N Arber S Odes M Moshkowitz D Keter I Pomeranz Y Ron I Reisfeld E Broide A Lavy A Fich R Eliakim J Patz E Bardan Y Villa T Gilat | 1996 | Gastroenterology1996，，： | 1 |
| 6 | The role of lowdose aspirin in the prevention of eolorectal caneer显示文摘 | Avivi D Moshkowitz M Detering E | 2012 | Expert Opin Ther Targets2012，16，1： | 1 |
| 7 | Point/Counterpoint: Aspirin is clinically effective in chemoprevention of colorectal neoplasia point 显示文摘 | Leshno M Moshkowitz M Arber N | 2008 | Cancer Epidemiol Biomarkers Prev2008，17，7： | 1 |
| 8 | prevalence of colorectal neoplasms in young, average risk individuals: A turning tide between East and West显示文摘AIM To determine the prevalence of colorectal neoplasia in average risk persons 40-59 years of age in Israel and to compare the results with other populations. METHODS We reviewed the results of asymptomatic average-risk subjects, aged 40 to 59 years, undergoing their first screening colonoscopy between April 1994 and January 2014. The detection rates of adenoma, advanced adenoma(AA) and colorectal cancer(CRC) were determined in the 40's and 50's age groups by gender. The prevalence of lesions was compared between age groups. After meticulous review of the literature, these results were compared to published studies addressing the prevalence of colorectal neoplasia in similar patient groups, in a variety of geographical locations.RESULTS We included first screening colonoscopy results of 1750 individuals. The prevalence of adenomas, AA and CRC was 8.3%, 1.0% and 0.2% in the 40-49 age group and 13.7%, 2.4% and 0.2% in the 50-59 age group, respectively. Age-dependent differences in adenoma and AA rates were significant only among men(p < 0.005). Literature review disclosed 17 relevant studies. As expected, in both Asian and Western populations, the risks for overall adenoma and advanced adenoma was significantly higher in the 50's age group as compared to the 40's age group in a similar fashion. The result of the current study were similar to previous studies on Western populations. A substantially higher rate of adenoma, was observed in studies conducted among Asian populations in both age groups.CONCLUSION The higher rate of colorectal neoplasia in Asian populations requires further investigation and reconsideration as to the starting age of screening in that population. | Ari Leshno Menachem Moshkowitz Maayan David Lior Galazan Alfred I Neugut Nadir Arber Erwin Santo | 2016 | World Journal of Gastroenterology2016，22，32： | 1 |
| 9 | Metachronous Bilateral Isolated Adrenal Metastasis from Rectal Adenocarcinoma: A Case Report显示文摘 | H. Jabir N. Tawfiq M. Moukhlissi M. Akssim A. Guensi B. Kadiri Z. Bouchbika A. Taleb N. Benchekroun H. Jouhadi S. Sahraoui S. Zamiati A. Benider I. C. Lawrance T. Matsuda M. Moshkowitz Y. Nakayama | 2014 | Case Reports in Gastrointestinal Medicine2014，，： | 1 |
| 10 | Seasonal variation in the frequency of Helicobacter pylori infection: a possible cause of the seasonal occurrence of peptic ulcer disease 显示文摘 | Moshkowitz M Konikoff FM Arber N | 1994 | Am J Gastroenterol1994，89，5： | 1 |
| 11 | Effect of phospholipids and their molecular species on cholesterol solubility and nucleation in human and model biles显示文摘 | Halper Z Moshkowitz M Laufer H | 1993 | Gut1993，34，2： | 1 |
| 12 | Ochronosis and aortic valve stenosis显示文摘 | Butany JW Naseemuddin A Moshkowitz Y | 2006 | J Card Surg2006，21，2： | 1 |
| 13 | High Helicobacter pylori numbers are associated with low eradication rate after triple therapy 显示文摘 | Moshkowitz M Konikoff FM Peled Y | 1995 | Gut1995，36，6： | 1 |
| 14 | The role of low-dose as- pirin in the prevention of colorectal cancer 显示文摘 | Avivi D Moshkowitz M Detering E | 2012 | Expert Opin Ther Tar- gets2012，16，1： | 1 |
| 15 | Halitosis and gastroesophageal reflux disease: A possible associa- tion显示文摘 | Moshkowitz M Horowitz N Leshno M | 2007 | Oral Dis2007，13，6： | 1 |
| 16 | 视频胶囊内镜诊断小肠肿瘤在胃肠道息肉综合征患者中应用的初步经验 | Barkay O. Moshkowitz M. Fireman Z. N. Arber 尹勇 | 2006 | 世界核心医学期刊文摘(胃肠病学分册)2006，0，1： | 0 |
| 17 | Incidence of colorectal neoplasms among male pilots显示文摘AIM: To assess the prevalence of colorectal neoplasms(adenomas, advanced adenomas and colorectal cancers) among Israeli military and commercial airline pilots.METHODS: Initial screening colonoscopy was performed on average-risk(no symptoms and no family history) airline pilots at the Integrated Cancer Prevention Center(ICPC) in the Tel-Aviv Medical Center. Visualized polyps were excised and sent for pathological examination. Advanced adenoma was defined as a lesion >10 mm in diameter, with high-grade dysplasia or villous histology. The results were compared with those of an age- and gender-matched random sample of healthy adults undergoing routine screening at the ICPC.RESULTS: There were 270 pilots(mean age 55.2 ± 7.4 years) and 1150 controls(mean age 55.7 ± 7.8 years). The prevalence of colorectal neoplasms was 15.9% among the pilots and 20.6% among the controls(P = 0.097, χ2 test). There were significantly more hyperplastic polyps among pilots(15.5% vs 9.4%, P = 0.004) and a trend towards fewer adenomas(14.8% vs 20.3% P = 0.06). The prevalence of advanced lesions among pilots and control groups was 5.9% and 4.7%, respectively(P = 0.49), and the prevalence of cancer was 0.7% and 0.69%, respectively(P = 0.93).CONCLUSION: There tends to be a lower colorectal adenoma, advanced adenoma and cancer prevalence but a higher hyperplastic polyp prevalence among pilots than the general population. | Menachem Moshkowitz Ohad Toledano Lior Galazan Aharon Hallak Nadir Arber Erwin Santo | 2014 | World Journal of Gastroenterology2014，20，27： | 0 |
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