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| 1 | Efficacy and safety of Amla(Phyllanthus emblica L.) in non-erosive reflux disease:a double-blind,randomized,placebo-controlled clinical trial显示文摘Background: Gastroesophageal reflux disease(GERD) is one of the most common gastrointestinal complaints. GERD, caused by the reflux of stomach contents into the esophagus, leads to troublesome symptoms such as heartburn and regurgitation. It is classified into two types: erosive esophagitis,characterized by visible esophageal mucosa erosion in endoscopy, and non-erosive reflux disease(NERD). GERD is a chronic and recurrent disease that impairs the quality of life and imposes socioeconomic and therapeutic burdens to both patients and society.Objective: Due to the failure of the conventional treatments for GERD and to the traditional use of Amla(Phyllanthus emblica L.), in addition to beneficial effects shown in recent studies, we evaluated the safety and efficacy of Amla tablet for improvement of symptoms of patients with NERD.Design, setting, participants and interventions: We designed a double-arm, randomized, double-blind,placebo-controlled clinical trial. Sixty-eight patients who had classic symptoms of GERD(heartburn,regurgitation and epigastralgia) for at least three months before the start of the trial were randomized in two parallel groups. Patients in the Amla group received two 500 mg Amla tablets twice a day, after meals,for 4 weeks. In the control group, patients received placebo tablets similar to the Amla prescription.Main outcome measures: The patients were visited at baseline, and at the end of the 2 nd and 4 th weeks of intervention; their symptoms were measured on a frequency and severity scale for the symptoms of NERD,according to the quality of life in reflux-associated disease questionnaire.Results: Frequencies of heartburn and regurgitation in both groups of the study were significantly reduced after intervention(P < 0.001). Repeated measures logistic regression analysis showed that, in the Amla group, there was a more significant reduction in regurgitation frequency, heartburn frequency, regurgitation severity and heartburn severity during the study period, compared with the placebo group(P < 0.001).Conclusion: This randomized double-blind, placebo-controlled clinical trial demonstrated that Amla could reduce frequencies of heartburn and regurgitation and improve heartburn and regurgitation severity in patients with NERD. | Shahnaz Karkon Varnosfaderani Fataneh Hashem-Dabaghian Gholamreza Amin Mahbubeh Bozorgi Ghazaleh Heydarirad Esmaeil Nazem Mohsen Nasiri Toosi Seyed Hamdollah Mosavat | 2018 | Journal of Integrative Medicine2018，16，2： | 7 |
| 2 | Complementary and alternative medicine use in Iranian patients with diabetes mellitus显示文摘OBJECTIVE: There is increasing interest in complementary and alternative medicine generally, and especially by those affected by chronic diseases, such as diabetes mellitus. We aimed to determine the prevalence and pattern of complementary and alternative medicine use among patients suffering from diabetes mellitus in Shiraz, southern Iran. Another objective was to explore associated factors for use of complementary and alternative medicine among patients with diabetes mellitus.METHODS: A 19-item semi-structured questionnaire(open- and close-ended) was administered to 239 patients with diabetes mellitus in this cross-sectional study. It was carried out in two outpatient diabetes clinics affiliated with the Shiraz University of Medical Sciences, Shiraz, Iran.RESULTS: One hundred and eighty patients(75.3%) used at least one type of complementary and alternative medicine in the last year prior to the interview. Patients with diabetes mellitus who were living in a large family(≥ 5 members), not taking insulin, and believed that complementary and alternative medicine have synergistic effects with conventional medicine, were independently and significantly(P values: 0.02, 0.04, and 0.01, respectively) more likely to use complementary and alternative medicine. Most of the users(97.7%) reported use of herbal preparations, and 89.4% of users did not change their medication, neither in medication schedule nor its dosage.CONCLUSION: The use of complementary and alternative medicine, especially herbal remedies, is popular among diabetes patients in Shiraz, Iran. This use is associated with patients' family size, type of conventional medications and their view about concomitant use of complementary and conventional medicine. | Mohammad Hashem Hashempur Mojtaba Heydari Seyed Hamdollah Mosavat Seyyed Taghi Heydari Mesbah Shams | 2015 | Journal of Integrative Medicine2015，13，5： | 5 |
| 3 | The use of Chinese herbal drugs in Islamic medicine显示文摘This paper investigates some of the ways that Chinese medicine has been transferred to the Western world and to Islamic territories. During the Golden Age of Islam(8th to 13 th century CE), the herbal drug trade promoted signifi cant commercial and scientifi c exchange between China and the Muslim world. Chinese herbal drugs have been described by medieval Muslim medical scholars such as Tabari(870 CE), Rhazes(925 CE), Haly Abbas(982 CE), Avicenna(1037 CE) and Jurjani(1137 CE). The term al-sin(the Arabic word for China) is used 46 times in Avicenna's Canon of Medicine in reference to herbal drugs imported from China. Cinnamon(dar sini; 'Chinese herb'), wild ginger(asaron), rhubarb(rivand-e sini), nutmeg(basbasa), incense tree wood(ood), cubeb(kababe) and sandalwood(sandal) were the most frequently mentioned Chinese herbs in Islamic medical books. There are also multiple similarities between the clinical uses of these herbs in both medical systems. It appears that Chinese herbal drugs were a major component of the exchange of goods and knowledge between China and the Islamic and later to the Western world amid this era. | Mojtaba Heyadri Mohammad Hashem Hashempur Mohammad Hosein Ayati Detlev Quintern Majid Nimrouzi Seyed Hamdollah Mosavat | 2015 | Journal of Integrative Medicine2015，13，6： | 4 |
| 4 | Efficacy of a traditional Persian medicine preparation for radiation-induced xerostomia:a randomized,open-label,active-controlled trial显示文摘BACKGROUND: Xerostomia is one of the most common side effects of radiation therapy among patients with head and neck cancers(HNC). However, conventional medicine lacks an effective treatment for radiation-induced xerostomia.OBJECTIVE: Synthesizing the traditional use of Alcea digitata and Malva sylvestris with their known beneficial effects from recent studies, we evaluated the efficacy of the herbs in the quality of life(QOL) of HNC patients with radiation-induced xerostomia.DESIGN, SETTING, PARTICIPANTS AND INTERVENTIONS: This study is a randomized, double-arm, open-label active-controlled clinical trial. We evaluated the effect of A. digitata and M. sylvestris on QOL of HNC patients with radiation-induced xerostomia compared with Hypozalix(artificial saliva). Patients were enrolled from the Imam Hossein Hospital's oncology clinic in Shahid Beheshti University of Medical Sciences, Tehran, Iran.MAIN OUTCOME MEASURES: Primary outcome measures in this trial were changes in patients' QOL assessed by the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire, Head and Neck Module(EORTC QLQ-H&N 35).RESULTS: Between-group analysis showed that the intervention group patients obtained significantly lower(better) total EORTC QLQ-H&N 35 scores as compared to the control group at the end of the intervention period(P = 0.007). Mean scores of dry mouth of EORTC QLQ-H&N 35 was also significantly lower(better) in the intervention group as compared to the control group(P = 0.017).CONCLUSION: Traditional Persian medicine preparation of hollyhocks and common mallow should be considered as a suitable treatment for xerostomia and improving QOL in HNC patients with radiation-induced xerostomia.TRIAL REGISTRATION: The trial was registered in Clinical Trials.gov with Identifier: NCT02854358. | Ghazaleh Heydarirad Hossein Rezaeizadeh Rasool Choopani Seyed Hamdollah Mosavat Ahmad Ameri | 2017 | Journal of Integrative Medicine2017，15，3： | 2 |
| 5 | Electrodeposition of nanocrystalline Zn–Ni alloy from alkaline glycinate bath containing saccharin as additive显示文摘 | S.H. Mosavat M.E. Bahrololoom M.H. Shariat | 2011 | Applied Surface Science2011，，20： | 1 |
| 6 | Study of corrosion performance of electrodeposited nanocrystalline Zn-Ni alloy coatings显示文摘 | Mosavat S H Shariat M H Bahrololoom M E | | 0，，： | 1 |
| 7 | Study of corrosion performance of electrodeposited nanocrystalline Zn-Ni alloy coatings显示文摘 | Mosavat S H Shariat M H Bahrololoom M E | | 0，，： | 1 |
| 8 | The medieval Persian manuscript of Afyunieh:the first individual treatise on the opium and addiction in history显示文摘According to historical evidence, the abuse of opium has been reported all over the globe—specifically throughout Eastern nations—since the sixteenth century. Before that, opium had mostly been applied as medication. Reference has been made in traditional Persian medical literature to the method of cultivation, properties, side effects and toxicity. In sixteenth century Iran, during the reign of the Safavids,opium abuse began. It was from then that prominent Persian scholars started to think of solutions to this societal problem. One of the most famous scholars was Imad al-Din Mahmud ibn Mas' ud Shirazi, who composed a book concerning addiction—Afyunieh, a comprehensive book on the topic of opium and all issues of opium. Furthermore, he recommended methods for reducing opium dose as well as substitution with other medications that had a narrower range of side effects, in order to eradicate dependency upon opium and opium-derived materials. This is most likely the first book that comprehensively addressed opium and discussed drug rehabilitation methodology, in traditional Persian medical literature. In this historical review, the authors have introduced the book Afyunieh, which presents methods for treating addiction to and giving up opium; the text comprises a synthesis of the author's opinions, professional experience and references to the work of other famous physicians. | Abdolali Moosavyzadeh Farzaneh Ghaffari Seyed Hamdollah Mosavat Arman Zargaran Azarakhsh Mokri Soghrat Faghihzadeh Mohsen Naseri | 2018 | Journal of Integrative Medicine2018，16，2： | 1 |
| 9 | Evaluation of point mutation detection in Mycobacterium tuberculosis with isoniazid resistance using real-time PCR and TaqMan probe assay显示文摘 | Riahi F Derakhshan M Mosavat A | 2015 | Appl Biochem Biotechnol2015，175，5： | 1 |
| 10 | Study ofcorrosion performance of electrodeposited nanocrystallineZn- Ni alloy coatings 显示文摘 | Mosavat S H Shariat M H Bahrololoom M E | 2012 | Corrosion Science2012，59，： | 1 |
| 11 | Study of corrosion performance of electrodeposited nanocrystalline Zn-Ni alloy coatings 显示文摘 | Mosavat S H Shariat M H Bahrololoom M E | 2012 | Corrosion Science2012，59，： | 1 |
| 12 | Study of corrosion performance of electrodeposited nanocrystalline Zn–Ni alloy coatings显示文摘 | S.H. Mosavat M.H. Shariat M.E. Bahrololoom | 2012 | Corrosion Science2012，，： | 1 |
| 13 | Study of cor- rosion performance of electrodeposited nanocrystalline Zn- Ni alloy coatings显示文摘 | Mosavat S H Shariat M H Bahrololoom M E | 2012 | Corrosion Science2012，59，： | 1 |
| 14 | Predicting Solvent Concentration Profile in the Porous Media Using Various Numerical Solutions to Convection-Dispersion Equation显示文摘 | Ali Abedini Farshid Torabi Nader Mosavat | 2012 | Journal of Mathematics and System Science2012，2，7： | 0 |
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