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| 1 | The role of the western Arabian Sea upwelling in Indian monsoon rainfall variability显示文摘 | Izumo T Montegut C B Luo J J | 2008 | J Climate2008，21，： | 1 |
| 2 | Estimation of the Agulhas ring impacts on meridional heat fluxes and transport using ARGO floats and satel- lite data 显示文摘 | SOUZA J MONTEGUT C D B CABANES C | 2011 | Geophysical Research Letters2011，38，21： | 1 |
| 3 | High refresh rate and oculomotor adaptation facilitate reading from video displays显示文摘 | Montegut MJ Bridgeman B Sykes J | 1997 | Spat Vis1997，10，4： | 1 |
| 4 | Mixed layer depth over the global ocean : an examination of profile data and a profile-based climatology 显示文摘 | DE BOYER MONTEGUT C MADEC G FISCHER A S | 2004 | J Geophys Res2004，109，12： | 1 |
| 5 | Comparison between three implementations of automatic identification algorithms for the quantification and characterization of mesoscale eddies in the South Atlantic Ocean 显示文摘 | SOUZA J M A C DE BOYER MONTEGUT C LE TRAON P Y | 2011 | Ocean Sci Discuss2011，8，： | 1 |
| 6 | The role of the western Arabian Sea upwelling in Indian monsoon rainfall variability显示文摘 | Izumo T C.De Boyer Montegut J.J.Luo S.K.Behera S.Masson and T.Yamagata | | 0，，： | 1 |
| 7 | Comparison between three implementations of automatic identification algo- rithms for the quantification and characterization of mesoscale eddies in the South Atlantic Ocean显示文摘 | SOUZA J M A C MONTEGUT C D B TRAON P Y L | 2011 | Ocean Science2011，7，3： | 1 |
| 8 | Stoichiometry of carbon, nitrogen and phosphorus in marine particulate matter显示文摘 | COPIN MONTEGUT C COPIN MONTEGUT G | 1983 | Deep-Sea Research1983，30，： | 1 |
| 9 | Mixed layer depth over the global ocean: an examination of profile data and a profile-based eli- matology显示文摘 | De Boyer Montegut C Madec G Fischer A S | 2004 | J Geophys Res2004，109，12： | 1 |
| 10 | A human tumor necrosis factor a mutant that binds exclusively to the p55 TNF receptor produces toxicity in the baboon 显示文摘 | Van Zee KJ Staekpole SA Montegut WJ | 1994 | J Exp Med1994，179，4： | 1 |
| 11 | An international consultation: The development of family medicine in Vietnam 显示文摘 | Montegut AJ Cartwright CA Schirmer JM | 2004 | Faro Med2004，36，5： | 1 |
| 12 | A human tumor nee-rosis factor a mutant that binds exclusively to the p55TNF receptor produces toxicity in the baboon显示文摘 | VAN ZEE K J STACKPOLE S A MONTEGUT W J | 2008 | J Exp Med2008，179，： | 1 |
| 13 | Mixed layer depth over the global ocean:an examination of profile data and a profile-based climatology显示文摘 | De Boyer Montegut C Madec G Fischer A S | | 0，，： | 1 |
| 14 | Effects of IL-10 on sys-temic inflammatory responses during sublethal primate endotoxemia显示文摘 | van der Poll T Jansen PM Montegut WJ | 1997 | J Immunol1997，158，： | 1 |
| 15 | Effects of IL-10 on systemic inflammatory responses during sublethal primateen dotoxemia显示文摘 | van der Poll T jansen PM Montegut WJ | 1997 | J Immunol1997，158，4： | 1 |
| 16 | The safety and efficacy of palbociclib in older patients with advanced breast cancer in a real-world setting显示文摘Aims:Palbociclib has been approved in combination with endocrine therapy(ET)for hormone receptor-positive(HR+)/human epidermal growth factor receptor 2-negative(HER2-)advanced breast cancer(ABC),regardless of age.Even though ABC is one of the most prevalent cancers in older patients,very few patients≥65 years old were included in pivotal trials.Therefore,the current study evaluated the safety and efficacy of palbociclib in“real-world”routine treatment of unselected older patients with HR+/HER2-ABC.Methods:Data were collected on patients>70 years old who were treated with palbociclib plus ET for HR+/HER2-ABC in our institution.We analyzed safety data(CTCAE v4.0 criteria)and outcomes,such as progression-free survival(PFS)and overall survival(OS),as well as any associations between main geriatric characteristics and our results.Furthermore,we assessed safety at a national level by analyzing all palbociclib-related adverse events(AEs)reported in the French Pharmacovigilance Database(FPVD)during the same period.Results:From February 2016 to July 2019,52 patients were identified with a median age of 80.9 years,of whom 88%presented an AE.The most common grade 3-4 AE was neutropenia(64%).Median PFS and OS were nine months and not reached,respectively.The FPVD reports 227 cases of palbociclib-related AEs,with older and younger patients sharing similar characteristics.Conclusion:Palbociclib is well tolerated in older patients with efficacy comparable to that in younger patients.However,the addition of palbociclib to ET should be evaluated individually in this older and frailer subgroup. | Etienne Gouton Louis Tassy Joëlle Micallef Amir Meskine Renaud Sabatier Maud Cecile-Herry Cécile Braticevic Anthony Goncalves Frederic Viret Alexandre de Nonneville Coline Montegut Franck Rouby Frederique Rousseau | 2022 | Journal of Cancer Metastasis and Treatment2022，8，1： | 0 |
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