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| 1 | 玻璃体腔组织纤溶酶原激活剂治疗玻璃体黄斑粘连(英文)显示文摘目的:评估仅玻璃体腔注射组织纤溶酶原激活剂(TPA)对玻璃体黄斑牵引以及玻璃体腔注射TPA和贝伐单抗对视网膜血管疾病的改善作用。方法:前瞻性研究。对24例24眼患者进行干预性系统研究。其中5眼玻璃体黄斑牵引综合征(VMT),19眼视网膜血管疾病包括:糖尿病黄斑水肿(DME)眼,糖尿病性玻璃体出血(VH)眼,视网膜中央静脉阻塞(CRVO)和新生血管年龄相关性黄斑变性眼(AMD)。在注射前及注射1mo后分别进行视力,B超和OCT检查。3眼VMT接受玻璃体腔单次注射TPA50μg,2眼接受100μg注射。19例视网膜血管疾病患者接受玻璃体腔组织纤溶酶原激活剂(50μg)和贝伐单抗(1.25 mg)联合治疗。结果:纳入病例中男性10眼视网膜血管疾病和VMT患者平均年龄分别为56.8y和60.4y。纳入病例中男性10眼(41.7%),女性14眼(58.3%)。22眼(91.7%)晶状体眼,2眼(8.3%)人工晶状体眼。VMT和视网膜血管疾病的玻璃体后部脱离(PVD)分别为0(0/5)和57.8%(11/19)(P=0.04)。在改善最佳矫正视力(BCVA)和降低黄斑中心凹厚度(CMT)方面,与无PVD眼相比,有PVD眼改善更多。结论:在VMT患者中,单独玻璃体腔内注射TPA不能成功诱导玻璃体后部完全脱离。玻璃体腔联合注射TPA和贝伐单抗可引起视网膜血管疾病患者玻璃体后部脱离,提高最佳矫正视力以及降低黄斑中心凹厚度。 | Saeed Karimi Masoud Soheilian Homayoun Nikkhah Azadeh Haseli Mofrad | 2018 | 国际眼科杂志2018，18，2： | 3 |
| 2 | Clinical and histologic spectrum of nonalcoholic fatty liver disease associated with normal ACT values显示文摘 | Mofrad P Contos MJ Hague M | 2003 | Hopatology2003，37，6： | 1 |
| 3 | A pilot study of vitamin E versus vitamin E and pioglitazone for the treatment of nonalcoholic steatohepatitis显示文摘 | Arun J. Sanyal Pouneh S. Mofrad Melissa J. Contos Carol Sargeant Velimir A. Luketic Richard K. Sterling R. Todd Stravitz Mitchell L. Shiffman John Clore Alan S. Mills | 2004 | Clinical Gastroenterology and Hepatology2004，，12： | 1 |
| 4 | Determination of performance of non-ideal aluminized explosives显示文摘 | Keshavarz M H Teimuri Mofrad R Esmall Poor K | 2006 | J Hazard Mat A2006，137，： | 1 |
| 5 | Velocity of detonation at any initial density without using heat of formation of explosives显示文摘 | Keshavarz M H Teimuri Mofrad R Fareghi Alamdari R | 2006 | J Hazard Mat A2006，137，： | 1 |
| 6 | Mechanics and deformation of the nucleus in micropipette aspiration显示文摘 | Ashkan Vaziri Mohammand R Kaazempur Mofrad | 2007 | Journal of Biomechanics2007，，40： | 1 |
| 7 | Molecular mechanics of filamin's rod domain显示文摘 | KOLAHI K S MOFRAD M R | 2008 | Biophys J2008，94，3： | 1 |
| 8 | Vinculin activation is necessary for complete talin binding显示文摘 | Golji J Lam J Mofrad MR | 2011 | Biophys2011，100，2： | 1 |
| 9 | Cell adhesion and detachment on gold surfaces modified with a thiol-functionalized RGD peptide 显示文摘 | Yoon SH Mofrad MR | 2011 | Biomaterials2011，32，30： | 1 |
| 10 | Effect of mixed compounds on methane hydrate formation and dissociation rates and storage capacity显示文摘 | Ganji H Manteghian M Rahimi Mofrad H | 2007 | Fuel Processing Technology2007，88，9： | 1 |
| 11 | An unusual cause of incessant tachycardia显示文摘 | Mofrad PS Hsia HH | 2007 | Pacing Clin Electrophysiol2007，30，： | 1 |
| 12 | Clinical and histologic spectrum of nonalcoholic fatty liver disease associated with normal ALT values显示文摘 | Mofrad P Contos M J Haque M | 2003 | Hepatology2003，37，4： | 1 |
| 13 | A pilot study of vitamin E versus vitamin E and pioglitazone for the treatment of nonalcoholic steatohepatitis显示文摘 | Sanyal ALl Mofrad PS Contos MJ | 2004 | Clin Gastroenterol Hepatol2004，2，12： | 1 |
| 14 | Molecular Mechanics of Filamin’s Rod Domain显示文摘 | Kevin S. Kolahi Mohammad R.K. Mofrad | 2008 | Biophysical Journal2008，，3： | 1 |
| 15 | Clinical and histologic spectrum of nonalcoholic fatty liver disease associated with normal ALT values 显示文摘 | Mofrad P Contos M J Haque M | 2004 | Hepatology2004，39，4： | 1 |
| 16 | Synthesis of a new ionimprinted polymer material for separation and preconcen-tration of traces of uranyl ions显示文摘 | Sadeghi S Akbarzadeh Mofrad A | 2007 | React Funct Polym2007，67，： | 1 |
| 17 | Synthesis of a new ion imprinted polymer material for separation and preconcentration of traces of uranyl ions显示文摘 | Sadeghi S Mofrad A A | 2007 | Reactive and Functional Polymers2007，67，10： | 1 |
| 18 | Molecular mechanics of filamin's rod domain显示文摘 | KOLAHI K S MOFRAD M R | 2008 | Biophys J2008，94，3： | 1 |
| 19 | Clinical and histologic spectrum of nonalcoholic fatty liver disease associated with normal ALT values 显示文摘 | Mofrad P Contos M J Haque M | 2003 | Hepatology2003，37，6： | 1 |
| 20 | Molecular mechanics of Filamin's rod do- main显示文摘 | Kolahi KS Mofrad MR | 2008 | Biophys J2008，94，3： | 1 |
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