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| 1 | 最新AD研究用诊断标准:IWG-2标准显示文摘在过去的8年中,国际工作组织(IWG)和美国国立老化研究院-阿尔茨海默协会(NIA-AA)建立了阿尔茨海默病(AD)诊断标准,它能更好地定义AD的临床表型,整合了生物标记物于诊断流程中,并覆盖了疾病的全程。本意见书充分地权衡了IWG标准的优缺点,建议改进诊断框架。依据这些改进,AD的诊断变得简单,只要有恰当的AD临床表型(典型或不典型)和与AD的病理相一致的病理生理学生物标志物出现。我们认为疾病的下游的定位性生物标志,如容积性磁共振成像(MRI)和氟脱氧葡萄糖-正电子发射型计算机断层成像(FDG-PET)等,适合更好地测量和监测疾病过程。本文还详述了非典型性AD、混合性AD和AD临床前期的特异诊断标准。 | 陈刚 曹雯炜 俞羚 糜建华 Dubois B Feldman HH Jacova C Hampel H Molinuevo JL Blennow K DeK osky ST Gauthier S Selkoe D Bateman R Cappa S Crutch S Engelborghs S Frisoni GB Fox NC Galasko D Habert MO Jicha GA Nordberg A Pasquier F Rabinovici G Robert P Rowe C Salloway S Sarazin M Epelbaum S de Souza LC Vellas B Visser PJ Schneider L Stern Y Scheltens P Cummings JL | 2014 | 神经病学与神经康复学杂志2014，11，3： | 31 |
| 2 | Atomic bonding of precipitate and phase transformation of Al-Cu-Mg alloy 显示文摘 | CAO Y J HOU X H MO Q F | 2007 | J Alloys Compd2007，441，： | 1 |
| 3 | Two-kidney,two clip renovascular hypertensive rats can be used as stroke-prone rats显示文摘 | ZHANG Y MO J | 1998 | Stroke1998，29，8： | 1 |
| 4 | Interesting physical properties of the new spinel phase of Si《,3》N《,4》 and C《,3》N《,4》显示文摘 | Ouyang L Z and Ching W Y | 1999 | Physical Review Letters1999，83，： | 1 |
| 5 | Low prevalence of the metabolic syndrome but high occurrence of various metabolic disorders in Chinese women with polycystic ovary syndrome显示文摘 | Ni RM Mo Y Chen X | 2009 | Eur J Endocrinol2009，161，： | 1 |
| 6 | Utilization of a metabolic un- coupler,3 ,3' ,4' ,5-tetrachlorosalicylanilide (TCS) to re- duce sludge growth in activated sludge culture 显示文摘 | Chen G H Mo H K Liu Y | 2002 | Water Res2002，36，8： | 1 |
| 7 | A linear cross-coupled control system for high-speed maehining显示文摘 | ZHONG Q SHI Y MO J | 2002 | International Journal of Advanced Manufacturing Technology2002，19，8： | 1 |
| 8 | Noniso- thermal crystallization and melting behavior of poly(β- hydroxybutyrate)-poly(vinyl-acetate) blends显示文摘 | An Y X Li L X Dong L S Mo Z S Feng Z L | 1999 | J Polym Sci Part B: Polym Phys1999，37，5： | 1 |
| 9 | High growth of SWNTs and MWNTs from C2H2 decomposition over Co-Mo/MgO catalysts显示文摘 | SHAJIHAN M MO Y H FAZLE KIBRIA A K M | 2004 | Carbon2004，42，： | 1 |
| 10 | Posterior fossa epidural hema- tomas in children: clinical experience with 40 cases显示文摘 | Seneer A Aras Y Akcakaya MO | 2012 | Neurosurg Pediatr2012，9，2： | 1 |
| 11 | Phelligridimer A, a highly oxygenated and unsaturated 26-membered macrocyclic metabolite with antioxidant activity from the fungus PheUinus igniarius 显示文摘 | Wang Y Wang S J Mo S Y | 2005 | Organic Letters2005，7，21： | 1 |
| 12 | Characterization of Aroma compounds in Chinese rice wine Qu by solvent-assisted flavor evaporation and headspace solid-phase microextrac- tion 显示文摘 | Mo X L Xu Y Fan W L | 2010 | Journal of Agricultural and Food Chemistry2010，58，： | 1 |
| 13 | Kimuras disease:the CT and MRI characteristics in fifteen cases显示文摘 | Zhang R Ban X H Mo Y X | 2011 | Eur J Radioi2011，80，2： | 1 |
| 14 | Biochemical complementation of chalcone synthase mutants defines a role for flavonols in functional pollen显示文摘 | Mo Y Nagel C Taylor L P | 1992 | Proceedings of the National Academy of Sciences1992，89，15： | 1 |
| 15 | Zircon U-Pb dating and in-si- tu Hf isotopic analysis of Permian peraluminous granite in the Lha- sa terrane, southern Tibet: Implications for Permian collisional orogeny and paleogeography显示文摘 | Zhu D C Mo X X Niu Y L | 2009 | Tectonophysics2009，469，14： | 1 |
| 16 | Effect of the Woods-Saxon nuclear distribution on the chiral magnetic field in Relativ- istic Heavy-ion Collisions显示文摘 | Mo Y J Feng S Q Shi Y F | 2013 | Physical Review C2013，88，88： | 1 |
| 17 | Photocatalytic purification of volatile organic compounds in indoor air:a literature review显示文摘 | Mo J Zhang Y Q Xu J J | 2009 | Atmos Environ2009，43，14： | 1 |
| 18 | In situ quartz crystal microbalance studies of nickel hydrous oxide films in alkaline electrolytes显示文摘 | Mo Y Hwang E Scherson D | 1996 | J Electrochem Soc1996，143，1： | 1 |
| 19 | 显示文摘 | Cai W L Mo C M | 1999 | Appl Phys Lett1999，74，20： | 1 |
| 20 | Theoretical prediction of the structure and properties of cubic spinel nitrides显示文摘 | Mo S D Ouyang L Z | 2002 | Journal of the American Ceramic Society2002，85，： | 1 |
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