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| 1 | Structural modifications of Helicobacter pylori lipopolysaccharide:An idea for how to live in peace显示文摘In this review,we discuss the findings and concepts underlying the'persistence mechanisms'of Helicobacter pylori(H.pylori),a spiral-shaped,Gram-negative rod bacterium that was discovered as a gastric pathogen by Marshall and Warren in 1984.H.pylori colonizes the gastric mucosa of nearly half of the human population.Infections appear in early childhood and,if not treated,persist for life.The presence or absence of symptoms and their severity depend on multiple bacterial components,host susceptibility and environmental factors,which allow H.pylori to switch between pathogenicity and commensalism.Many studies have shown that H.pylori components may facilitate the colonization process and the immune response of the host during the course of H.pylori infection.These H.pylori-driven interactions might result from positive or negative modulation.Among the negative immunomodulators,a prominent position is occupied by a vacuolating toxin A(VacA)and cytotoxin-associated gene A(CagA)protein.However,in light of the recent studies that are presented in this review,it is necessary to enrich this panel with H.pylori lipopolysaccharide(LPS).Together with CagA and VacA,LPS suppresses the elimination of H.pylori bacteria from the gastric mucosa by interfering with the activity of innate and adaptive immune cells,diminishing the inflammatory response,and affecting the adaptive T lymphocyte response,thus facilitating the development of chronic infections.The complex strategy of H.pylori bacteria for survival in the gastric mucosa of the host involves both structural modifications of LPS lipid A to diminish its endotoxic properties and the expression and variation of Lewis determinants,arranged in O-specific chains of H.pylori LPS.By mimicking host components,this phenomenon leaves these bacteria'invisible'to immune cells.Together,these mechanisms allow H.pylori to survive and live for many years within their hosts. | Magdalena Chmiela Karolina Rudnicka Eliza Miszczyk | 2014 | World Journal of Gastroenterology2014，20，29： | 15 |
| 2 | Immunophenotype of peripheral blood natural killer cells and IL ‐10 serum levels in relation to Helicobacter pylori status显示文摘 | Karolina Rudnicka Agnieszka Matusiak Eliza Miszczyk Wies?awa Rudnicka Micha? Tenderenda Magdalena Chmiela | 2013 | APMIS2013，，9： | 2 |
| 3 | Reliability of Flue gas desulfurization instal- lations - the essential condition of efficient air pollution control显示文摘 | Miszczyk Darowicki K | 2002 | Polish Journal of Environment Studies2002，11，3： | 1 |
| 4 | Use of impedance spectroscopy to evaluate the durability of protective coatings after thermal shock 显示文摘 | Miszczyk A Darowicki K | 1998 | Corrosion Science1998，40，4： | 1 |
| 5 | Reliability of flue gas desulfurization installations - the essential condition of efficient air pollution control 显示文摘 | Miszczyk K Darowicki | 2002 | Polish Journal of Environmental Studies2002，21，3： | 1 |
| 6 | Surgical treatment of dyspla- sia fibrosa and defectus fibrosus with bone allografts 显示文摘 | Tomasik P Spindel J Miszczyk L | 2010 | Ortop Trau- matol Rehabil2010，12，1： | 1 |
| 7 | Linac based radical radioablation of liver tumors显示文摘 | Miszczyk L Tukiendorf A Jochymek B | 2013 | Technol Cancer Res Treat2013，12，3： | 1 |
| 8 | Improvement of electro- chemical action of zinc-rich paints by addition of nanopar- ticulate zinc 显示文摘 | SCHAEFER K MISZCZYK A | 2013 | Corrosion Science2013，66，： | 1 |
| 9 | Surgical treatment of dysplasia fibrosa and defectus fibresus with bone allografts显示文摘 | Tomasik P Spindel J Miszczyk L | 2010 | Orthop Traumatol Rehabil2010，12，1： | 1 |
| 10 | Interaction of Helico- bacter pylori with C-type lectin dendritic cell-specific ICAM grabbing nonintegrin显示文摘 | Miszczyk E Rudnicka K Moran AP | 2012 | J Biomed Biotechnol2012，2012，20： | 1 |
| 11 | Helicobacter pylori-driven modulation of NK cell expansion,intracellular cytokine expression and cytotoxic activity显示文摘 | Rudnicka K Miszczyk E Matusiak A | 2015 | Innate Immun2015，21，2： | 1 |
| 12 | Microstructure and texture evolution during annealing of plane strain compressed Al and Al-1%Mn alloy single crystals显示文摘 | MISZCZYK M PAUL H DRIVER J H | 2011 | Archives of Metallurgy and Materials2011，56，4： | 1 |
| 13 | Surgical treatment of dys pla- siafibrosa and defeetus fibrosus with bone allografts显示文摘 | Tomasik P Spindel J Miszczyk L | 2010 | Orthop Trau- matol Rehabil2010，12，1： | 1 |
| 14 | Surgical treatment ofdysplasia fibrosa and defectus fibrosus with bone allografts 显示文摘 | Tomasik P Spindel J Miszczyk L | 2010 | Orthop Traumatol Rehabil2010，12，1： | 1 |
| 15 | Improvement of electro chemical action of zinc-rich paints by addition of nano particulate zinc 显示文摘 | Schaefer K Miszczyk A | 2013 | Corrosion Science2013，66，： | 1 |
| 16 | Electrochemical approach to evaluate the interlayer adhesion of organic coatings显示文摘 | Miszczyk A Schauer T | 2005 | Progress in Organic Coatings2005，52，： | 1 |
| 17 | Improvement of electrochemical action of zinc-rich paints by addition of nanoparticulate zinc 显示文摘 | SCHAEFER K MISZCZYK A | 2013 | Corrosion Science2013，66，： | 1 |
| 18 | Evaluation of tolerance and efficacy of postoperative combined radiotherapy and chemotherapy in locally advanced gastric cancer 显示文摘 | Wydmanski J Suwinski R Miszczyk L | 2005 | Przegl Lek2005，62，12： | 1 |
| 19 | Radiotherapy for marginally resected, unresectable or recurrent giant cell tumor of the bone: a rare cancer network study显示文摘 | Bhatia S Miszczyk L Roelandts M | 2011 | Rare Tumors2011，3，4： | 1 |
| 20 | The influence of radio- therapy of head and neck cancers on carotid arteries 显示文摘 | Opielka W Miszczyk L Garstka T | 2014 | Przegl Lek2014，71，12： | 1 |
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