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| 1 | Conversion of laparoscopic colorectal resection for cancer: What is the impact on short-term outcomes and survival?显示文摘Laparoscopic resection for colon and rectal cancer is associated with quicker return of bowel function, reduced postoperative morbidity rates and shorter length of hospital stay compared to open surgery, with no differences in long-term survival. Conversion to open surgery is reported in up to 30% of patients enrolled in randomized control trials comparing open and laparoscopic colorectal resection for cancer. In this review, reasons for conversion are anatomical-related factors, disease-related-factors and surgeon-related factors. Body mass index, local tumour extension and co-morbidities are independent predictors of conversion. The current evidence has shown that patients with converted resection for colon cancer have similar outcomes compared to patients undergoing a laparoscopic completed or open resection. The few studies that have assessed the outcomes after conversion of laparoscopic rectal resection reported significantly higher rates of complications and longer length of hospital stay in converted patients compared to laparoscopically treated patients. No definitive conclusions can be drawn when converted and open rectal resections are compared. Early and pre-emptive conversion appears to have more favourable outcomes than reactive conversion; however, further large studies are needed to better define the optimal timing of conversion. With regard to long-term oncologic outcome, overall and disease-free survival in the case of conversion in laparoscopic colorectal cancer surgery seems to be worse than those achieved in patients in whom resection was successfully completed by laparoscopy. Although a worse long-term oncologic outcome has been suggested, it remains difficult to draw a proper conclusion due to the heterogeneity of the long-term outcomes as well as the inclusion of both colon and rectal cancer patients in most of the studies. Therefore, we discuss the currently available evidence of the impact of conversion in laparoscopic resection for colon and rectal cancer on both short-term outcomes and long-term survival. | Marco E Allaix Edgar JB Furnée Massimiliano Mistrangelo Alberto Arezzo Mario Morino | 2016 | World Journal of Gastroenterology2016，22，37： | 11 |
| 2 | Does water delivery affect pelvic floor? Ultrasound evaluation of perineal function 显示文摘 | Mistrangelo E Gaggero CR Nadalini C | 2007 | Arch Gynecol Obstet2007，276，2： | 1 |
| 3 | The value of sonohysterography in detecting intracavitary benign abnor-malities显示文摘 | Valenzano MM Lijoi D Mistrangelo E | 2005 | Arch Gynecol Obstet2005，272，4： | 1 |
| 4 | Rising use of synthetic mesh in transvaginal pelvic reconstructive surgery:A review of the risk of vaginal erosion 显示文摘 | Mistrangelo E Mancuso S Nadalini C | 2007 | J Minim Invasive Gynecol2007，14，5： | 1 |
| 5 | The value of sonohysterography in detecting intracavitary benign abnormalities显示文摘 | Valenzano MM Lijoi D Mistrangelo E | 2005 | Arch Gynecol Obstet2005，272，4： | 1 |
| 6 | Randomized study of laparoscopic versus minilaparotomic myomectomy for uterine myomas 显示文摘 | Alessandri F Lijoi D Mistrangelo E | 2006 | J Minim Invasive Gynecol2006，13，2： | 1 |
| 7 | A prospective,ran- domized trial comparing immediate versus delayed catheter removal following hysterectomy显示文摘 | Alessandri F Mistrangelo E Lijoi D | 2006 | Acta Obstet Gynecol Scand2006，85，6： | 1 |
| 8 | Transvaginal sonohysterographic evaluation of uterine malformations 显示文摘 | Valenzano MM Mistrangelo E Lijoi D | 2006 | Eur J Obstet Gyneeol Reprod Biol2006，124，2： | 1 |
| 9 | Vaginalultra2sonographic and hysterosonographic evaluation of the low transverse incision after cesarean section:correlation with gynaecological symptoms显示文摘 | Menada Valenzano M Lijoi D Mistrangelo E | 2006 | Gynecol Obstet Invest2006，61，4： | 1 |
| 10 | MRI appearance of the low transverse incision after caesarean section in a symptomatic woman 显示文摘 | Lijoi D Biscaldi E Mistrangelo E | 2006 | European Journal of Radiology Extra2006，59，： | 1 |
| 11 | Complications of the surgicaltreatment of hemorrhoids and its therapy显示文摘 | Corno F Muratore A Mistrangelo M | 1995 | Ann Ital Chir1995，66，6： | 1 |
| 12 | Randomized study of laparoscopic versus minilaparotomic myomectomy for uterine myomas 显示文摘 | Alessandri F Lijoi D Mistrangelo E | 2006 | J Minim Invasive Gynecol2006，13，： | 1 |
| 13 | MR1 appearanceof the low transverse incision after caesarean section in asymptomatic woman显示文摘 | Davide L Biscaldi E Mistrangelo E | 2006 | Eur J Radiol Extra2006，59，3： | 1 |
| 14 | The treatment of squamous a- nal carcinoma:guidelines of the Italian Society of Colo-Rectal Surgery 显示文摘 | I Giani M Mistrangelo C Fucini | 2013 | Techniques in coloproctology2013，17，2： | 1 |
| 15 | The value of sonohyst-erography in detecting intracavitary benign abnormalities显示文摘 | VALENZANO M M LIJOI D MISTRANGELO E | 2005 | Arch Gynecol Obstet2005，272，4： | 1 |
| 16 | Laparoscopic versus open resection for transverse colon cancer 显示文摘 | Mistrangelo M Allaix ME Cassoni P | 2015 | Surg Endosc2015，29，8： | 1 |
| 17 | Complications of the surgical treatment of hemorrhoids and its therapy显示文摘 | CORNO F MURATORE A MISTRANGELO M | 1995 | Am Ital Chir1995，66，6： | 1 |
| 18 | Randomized study of laparoscopic versus minilaparotomic myomectomy for uterine myomas显示文摘 | Alessandri F Lijoi D Mistrangelo E | 2006 | J Minim Invasive Gynecol2006，13，2： | 1 |
| 19 | MRI appearance of the low transverse incision after caesarean section in a symptomatic woman显示文摘 | Davide Lijoi Ennio Biscaldi Emanuela Mistrangelo Stefano Bogliolo Nicola Ragni | 2006 | European Journal of Radiology Extra2006，，3： | 1 |
| 20 | A prospective, randomized trial comparing immediate versus delayed catheter removal following hysterectomy 显示文摘 | Alessandrl F Mistrangelo E Lijoi D | 2006 | Acta Obstet Gynecol Scand2006，85，6： | 1 |
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