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| 1 | Enhanced electrogastrography: A realistic way to salvage a promise that was never kept?显示文摘AIM To enhance the clinical utility of electrogastrography(EGG), which has been recorded since 1922, but is clinically unutilized.METHODS An innovative method to salvage the promise of EGG is proposed by introducing a preliminary procedure, while maintaining the electrodes, standardized equipment, and signal processing utilized in the well-established EGG testing of today. The proposed enhanced EGG(EEGG) protocol involves swallowing an ingestible capsule containing miniature electronic oscillator embedded in an expandable, self-disintegratable, biocompatible pseudobesoar residing in the stomach for the duration of the test. The benefits of the proposed approach are outlined, tested and discussed in details. RESULTS Experiments were performed on eight mongrel dogs(6F, 4M, 23.8 ± 3.3 kg). Four were administered an active EEGG capsule, while the rest were given a deactivated(battery removed) capsule. Pharmacologically facilitated gastric motility revealed a significant(P < 0.01) Pearson correlation between gastric motility indices obtained by force transducers implanted directly on the stomach, and the motility indices obtained by EEGG. A particular emphasis was made on preserving standard EGG-related hardware and software in order to facilitate the introduction of the proposed EEGG in environments which already utilize standard EGG testing. Theexpanded intragastric pseudobezoar containing the miniature electronic oscillator was retained during the tests, and could be disintegrated on demand. CONCLUSION Enhancing standard EGG by an ingestible, selfexpanding and self-disintegrating pseudobesoar containing a miniature electronic oscillator can be an important avenue for clinical applicability of this test. | Michael D Poscente Martin P Mintchev | 2017 | World Journal of Gastroenterology2017，23，25： | 2 |
| 2 | Colometer:A real-time quality feedback system for screening colonoscopy显示文摘AIM:To investigate the performance of a new software-based colonoscopy quality assessment system.METHODS:The software-based system employs a novel image processing algorithm which detects the levels of image clarity,withdrawal velocity,and level of the bowel preparation in a real-time fashion from live video signal.Threshold levels of image blurriness and the withdrawal velocity below which the visualization could be considered adequate have initially been determined arbitrarily by review of sample colonoscopy videos by two experienced endoscopists.Subsequently,an overall colonoscopy quality rating was computed based on the percentage of the withdrawal time with adequate visualization(scored 1-5;1,when the percentage was 1%-20%;2,when the percentage was 21%-40%,etc.).In order to test the proposed velocity and blurriness thresholds,screening colonoscopy withdrawal videos from a specialized ambulatory colon cancer screening center were collected,automatically processed and rated.Quality ratings on the withdrawal were compared to the insertion in the same patients.Then,3 experienced endoscopists reviewed the collected videos in a blinded fashion and rated the overall quality of each withdrawal(scored 1-5;1,poor;3,average;5,excellent) based on 3 major aspects:image quality,colon preparation,and withdrawal velocity.The automated quality ratings were compared to the averaged endoscopist quality ratings using Spearman correlation coefficient.RESULTS:Fourteen screening colonoscopies were assessed.Adenomatous polyps were detected in 4/14(29%) of the collected colonoscopy video samples.As a proof of concept,the Colometer software rated colonoscope withdrawal as having better visualization than the insertion in the 10 videos which did not have any polyps(average percent time with adequate visualization:79% ± 5% for withdrawal and 50% ± 14% for insertion,P < 0.01).Withdrawal times during which no polyps were removed ranged from 4-12 min.The median quality rating from the automated system and the reviewers was 3.45 [interquartile range(IQR),3.1-3.68] and 3.00(IQR,2.33-3.67) respectively for all colonoscopy video samples.The automated rating revealed a strong correlation with the reviewer's rating(ρ coefficient= 0.65,P = 0.01).There was good correlation of the automated overall quality rating and the mean endoscopist withdrawal speed rating(Spearman r coefficient= 0.59,P = 0.03).There was no correlation of automated overall quality rating with mean endoscopists image quality rating(Spearman r coefficient= 0.41,P = 0.15).CONCLUSION:The results from a novel automated real-time colonoscopy quality feedback system strongly agreed with the endoscopists' quality assessments.Further study is required to validate this approach. | Dobromir Filip Xuexin Gao Leticia Angulo-Rodriguez Martin P Mintchev Shane M Devlin Alaa Rostom Wayne Rosen Christopher N Andrews | 2012 | World Journal of Gastroenterology2012，18，32： | 2 |
| 3 | Measurment while drilling surveying of highly inclinedand horizontal well sections utilizing single axis gyrosensingsystem 显示文摘 | NOURELDIN A IRVINE- HALLIDAY D MINTCHEV MP | 2004 | Mearurement Science and Technology2004，15，12： | 1 |
| 4 | Measurement- while-drilling surveying of highly inclined and horizontal well sections utilizing single-axis gyro sensing system显示文摘 | Noureldin A Irvine-Halliday D Mintchev M P | 2004 | Measurement Science and Technology2004，15，12： | 1 |
| 5 | Microprocessor controlled movement of solid colonic content using sequential neural electrical stimulation显示文摘 | Amaris M A Rashev P Z Mintchev M P | 2002 | Gut2002，50，4： | 1 |
| 6 | Extracting quantitative information from digital electrogastrogram显示文摘 | Mintchev MP Bowes KL | 1996 | Med Biol Eng Comput1996，34，： | 1 |
| 7 | Measurement-while-drilling surveying of highly-in- clined and horizontal well sections utilizing single axis gyro sensing system显示文摘 | NOURELDIN A IRVINE-HALLIOAY D MINTCHEV M P | 2004 | Measurement Science and Tech- nology2004，15，12： | 1 |
| 8 | Observability Analysis for INS Alignment in Horizontal Drilling显示文摘 | Pech E Mintchev M P | 2007 | AEEE Transactions on instrumentation and Measurement2007，56，6： | 1 |
| 9 | Extracting quantitative information from digital electrogastrogram显示文摘 | MINTCHEV M P BOWES K L | 1996 | Med Biol Eng Comput1996，34，： | 1 |
| 10 | Fracture of metal/ceramic interfaces显示文摘 | C. Kohnle O. Mintchev D. Brunner S. Schmauder | 2000 | Computational Materials Science2000，，1： | 1 |
| 11 | Misinterpretation of human electrogastrograms related to inappropriate data conditioning and acquisition using digital computers显示文摘 | Rashev PZ Bowes KL | 2000 | Dig Dis Sci2000，45，11： | 1 |
| 12 | Microprocessor controlled movement of liquid gastric content using sequential neural electrical stimulation显示文摘 | Mintchev MP Sanmiguel CP Otto SJ | 1998 | Gut1998，43，5： | 1 |
| 13 | 显示文摘 | Sanmiguel CP Amaris M | 2000 | Gastroenterology2000，118，： | 1 |
| 14 | Observability analysis for INS alignment in horizontal drilling 显示文摘 | PECHT E MINTCHEV M P | 2007 | IEEE Trans Instrum Meas2007，56，5： | 1 |
| 15 | Impact of external factors on the stability of human electrogas-trograms 显示文摘 | BOWES K L | 1996 | Med Biol Comput1996，34，： | 1 |
| 16 | High expression of Foxp3, IL-23p19 and survivin mRNA in colorectal carcinoma 显示文摘 | Stanilov N Miteva L Mintchev N | 2009 | Int J Colorectal Dis2009，24，2： | 1 |
| 17 | Adaptive Compensation of the Mud Pump Noise in a Meas- urement- while-- drilling System显示文摘 | Brandon T L Mintchev M P Tabler H | 1999 | SPE Journal1999，4，2： | 1 |
| 18 | Adaptive compensation of the mud pump noise in a measurement while-drilling system 显示文摘 | Brandon T L Mintchev M P Tabler H | 1999 | SPE Journal1999，4，2： | 1 |
| 19 | Measurement-while- drilling surveying of highly inclined and horizontal well sections utilizing single-axis gyro sensing system显示文摘 | Noureldin A Irvine-Halliday D Mintchev M P | 2004 | Measurement Science and Technology2004，15，12： | 1 |
| 20 | Electrical Activity from Colon Overlaps with Normal Gastric Electrical Activity in Cutaneous Recordings显示文摘 | Manuel A. Amaris Claudia P. Sanmiguel Daniel C. Sadowski Kenneth L. Bowes Martin P. Mintchev | 2002 | Digestive Diseases and Sciences2002，，11： | 1 |
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