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| 1 | Overview of boosting options for future downsized engines显示文摘Driven by a demand for better fuel economy and increasingly stringent emissions regulations over a wide range of customers and applications,engine manufacturers have turned towards engine downsizing as the most potent enabler to meet these requirements.With boosting systems becoming ever more numerous as the technical solutions to complex boosting requirements of the internal combustion engine increase,it is time for an overview of available and under development boosting technologies and systems and for a discussion of their relevance to downsizing efforts.The presented analysis shows that there are no standard solutions for all the different applications as the trends indicate a rising complexity to meet with the extreme boosting requirements predicted for the remainder of the decade.These trends include variable geometry,a shift from single to two(or more)stages,extensive actuation for bypassing exhaust flows,exhaust flow regulation and pulsating exhaust energy recovery, severe electrification and an extensive effort downstream from the turbine to capture waste heat after the principal turbo- charger/supercharger system. | RICARDO Martinez-Botas APOSTOLOS Pesiridis YANG MingYang | 2011 | Science China(Technological Sciences)2011，54，2： | 13 |
| 2 | Effect of Sanhuangwuji powder,anti-rheumatic drugs,and ginger-partitioned acupoint stimulation on the treatment of rheumatoid arthritis with peptic ulcer:a randomized controlled study显示文摘OBjECTIVE:To observe the efficacy and safety of oral Sanhuangwuji powder,anti-rheumatic drugs(ARDs),and ginger-partitioned acupoint stimulation at Zusanli(ST 36) on the treatment of rheumatoid arthritis(RA) complicated by peptic ulcer.METHODS:This prospective randomized controlled study included 180 eligible inpatients and outpatients randomly assigned to an ARD treatment(n = 60),ginger-partitioned stimulation(n =60),or combination treatment(n = 60).Patients assigned to the ARD group were given oral celecoxib,methotrexate,and esomeprazole.Patients assigned to theginger-partitioned stimulation group were given ginger-partitioned acupoint stimulation at Zusanli(ST 36) in addition to the ARDs.Patients in the combination treatment group were given oral Sanhuangwuji powder,ginger-partitioned acupoint stimulation at Zusanli(ST 36),and ARDs.All patients were followed up for 2 months to evaluate clinical effects and safety.The study was registered in the World Health Organization database at the General Hospital of Chengdu Military Area Command Chinese People's Liberation Army(ChiCTR-TCC12002824).RESULTS:The combination treatment group had significantly greater improvements in RA symptoms,laboratory outcomes,and gastrointestinal symptom scores,compared with the other groups(P < 0.05).The peptic ulcer healing rate in the combination treatment group was significantly greater than that in the ARD treatment group(x^2 = 16.875,P < 0.05) and the ginger-partitioned stimulation group(x^2 = 6.171,P<0.05).CONCLUSION:Combination treatment with ginger-partitioned acupoint stimulation at Zusanli(ST36),oral Sanhuangwuji powder,and ARDs had a better clinical effect for RA with complicated peptic ulcer,compared with ARD treatmentalone or in combination with ginger-partitioned acupoint stimulation. | Liu Defang Guo Mingyang Hu Yonghe Liu Taihua Yan Jiao Luo Yong Yun Mingdong Yang Min Zhang Jun Guo Linglin | 2015 | Journal of Traditional Chinese Medicine2015，35，3： | 9 |
| 3 | Facile electrodeposition of 3D concentration-gradient Ni-Co hydroxide nanostructures on nickel foam as high performance electrodes for asymmetric supercapacitors显示文摘小说三维(3D ) 集中坡度 Ni 公司氢氧化物 nanostructures (3DCGNC ) 被一个灵巧的逐步的电气化学的免职方法直接在镍泡沫上种了并且强烈地为 supercapacitors 调查同样没有文件夹、没有售票员的电极。基于一种三电极的电气化学的描述技术,获得的 3DCGNC 电极表明了 1,760 F 的一个高特定的电容 ???? | Mingyang Yang Hua Cheng Yingying Gu Zhifang Sun Jing Hu Lujie Cao Fucong Lv Minchan Li Wenxi Wang Zhenyu Wang Shaofei Wu Hongtao Liu Zhouguang Lu | 2015 | Nano Research2015，8，8： | 8 |
| 4 | Development mechanism of internal local corrosion of X80 pipeline steel显示文摘The occurrence and development mechanism of internal local corrosion has always been a controversial topic,and especially under flow conditions.In this paper,an improved high shear force loop was experimentally used,and local flow field is induced by simulating corrosion defects on the surface of X80 pipeline steel specimens.The characteristics of corrosion products deposited on the surface of specimens in CO2-saturated NACE solution were investigated by means of electrochemical impedance spectroscopy(EIS),scanning electron microscopy(SEM),X-ray diffraction(XRD),and energy dispersive spectrometry(EDS).The 3D micromorphology of the corrosion test surface after remove the corrosion scale used to measure the size of localized corrosion pit.Under the influence of local defects,the wall shear stress(WSS)and turbulent kinetic energy of local flow fields enhanced significantly,and pressure fluctuations in local flow field were induced.The results showed that the characteristics of surface corrosion products varied with flow velocity.The corrosion scales formed in various regions of specimens with defects exhibited different surface micro-morphologies and chemical compositions.Overall,these data offer new perspectives for better understanding the mechanisms behind local corrosion. | Zhuowei Tan Liuyang Yang Dalei Zhang Zhenbo Wang Frank Cheng Mingyang Zhang Youhai Jin | 2020 | Journal of Materials Science & Technology2020，47，14： | 6 |
| 5 | Research and development on transonic compressor of high pressure ratio turbocharger for vehicle internal combustion engines显示文摘The pressure ratio required for a turbocharger centrifugal compressor increases with internal combustion engine power density. High pressure ratio causes a transonic flow field at the impeller inducer. Transonic flow narrows the stable flow range and de-teriorates stage efficiency. In this work, an advanced high pressure ratio transonic compressor was designed. The experimental results show that the maximum pressure ratio of this turbocharger is about 4.2, the maximum efficiency is above 80% and the stable flow range at the designed rotating speed is up to 34%. A turbocharger with this transonic compressor has been applied to some vehicle research actually, and improved power density by 40%. | ZHENG XinQian, ZHANG YangJun & YANG MingYang State Key Laboratory of Automotive Safety and Energy, Tsinghua University, Beijing 100084, China | 2010 | Science China(Technological Sciences)2010，53，7： | 6 |
| 6 | Research progress of photocatalysis based on highly dispersed titanium in mesoporous SiO_2显示文摘With the development of the human economy and green chemistry, people pay much more attention to environmental safety. Correspondingly, mesoporous TiO_2 and its correlated photocatalysts are able to help people seek for better life. In this review, first of all, we briefly introduce the preparations and applications of mesoporous TiO_2-SiO_2 materials, which exhibit excellent performance in pollutants decomposition and H_2 evolution in photocatalysis. Then, we review the mesoporous composites of TiSiO_2 materials, which are ideal materials used in the photoreduction of air pollutants such as CO_2, NO and NO_2. It is powerfully evident from the literature surveys that these TiO_2 based mesoporous photocatalysts possess a large potential in environment and energy development. | Chencheng Dong Jiahui Ji Zhe Yang Yifei Xiao Mingyang Xing Jinlong Zhang | 2019 | Chinese Chemical Letters2019，30，4： | 5 |
| 7 | Effect of methotrexate combined with Sanhuang Yilong decoction on serum and synovial fluid aquaporin levels in rheumatoid arthritis dampness-heat blockage syndrome显示文摘OBJECTIVE:To study the effect of methotrexate(MTX) combined with Sanhuang Yilong decoction(SYD) on aquaporin(AQP) expression,and to explore the role of AQPs in the pathogenesis of rheumatoid arthritis(RA).METHODS:A total of 118 dampness-heat blockage type RA patients who were hospitalized in the General Chengdu Military Hospital between January2014 and December 2016 were selected as subjects in this study(30 patient of these patients with knee joint effusion were assigned to the RA synovial fluid group).For the pre-treatment controlgroups,30 healthy volunteers were recruited as the healthy control group and 30 osteoarthritis(OA) patients with knee joint effusion were included as OA synovial fluid control group.The RA dampnessheat blockage syndrome treatment groups were divided into 45 cases in the combined group and 45 cases in the MTX group.The combined group received MTX combined with SYD treatment while the MTX group received MTX alone.AQP1,AQP2 and AQP3 expressions were detected in the serum and synovial fluid.RESULTS:AQP1 had the highest expression,followed by AQP3,and AQP2.The serum levels of AQP1,AQP2 and AQP3 were all significantly lower than those in the healthy volunteers(P < 0.05),while the synovial fluid AQP1,AQP2 and AQP3 expression in the RA group were comparable to these in the OA groups(P > 0.05).After treatment for2 weeks,serum AQP1,AQP2,AQP3 were significantly increased and erythrocyte sedimentation rate,C-reactive protein,disease activity score of 28 joints were decreased in the combined group(P < 0.05).CONCLUSION:Abnormal expression of AQPs inhibits water metabolism in RA dampness-heat blockage syndrome,so liquid is accumulated at the joint,which may play an important role in the pathogenesis of RA.MTX combined with SYD for the treatment of RA can effectively increase AQP expression. | Liu Defang Yan Jiao Guo Mingyang Luo Yong Yang Mei Yang Min Zou Longfu Li Wan Zhong Xiaolong Liu Tao Hu Yonghe | 2018 | Journal of Traditional Chinese Medicine2018，38，4： | 4 |
| 8 | Selective depression action of taurine in flotation separation of specularite and chlorite显示文摘Chlorite,as the most representative gangue mineral associated with specularite,of which the separation of these two minerals is difficult.This paper investigated the depression effect of taurine on specularite/chlorite separation via flotation experiments,adsorption tests,contact angle measurements,Zeta potential detection,FT-IR measurements,and XPS analyses.The results of single mineral flotation indicated that chlorite could be depressed selectively by taurine with the recovery of less than 30%,but the floatability of specularite remains high with recovery rate of 81.77%at pH 10.The artificial mixed mineral flotation results confirmed the effectiveness of taurine as a depressant.Surface adsorption,contact angle,and Zeta potential detection revealed taurine primarily adsorbs on the chlorite surface,which hampered the DDA’s subsequent adsorption and results in the chlorite’s poor floatability.The FT-IR spectra and XPS analyses provided further proof that taurine adsorbed on chlorite surface as an electron donor,and part of the electrons transferred from the sulfonic acid group of taurine to metal ions during the adsorption process.In addition,the hydrogen bond between amino-group of taurine and O ions in chlorite surface was also formed in the adsorption process.Finally,optimized adsorption configurations of taurine on chlorite surfaces were proposed. | Mingyang Li Cheng Yang Zhaoyang Wu Xiangpeng Gao Xiong Tong Xiankun Yu Hongming Long | 2022 | International Journal of Mining Science and Technology2022，32，3： | 4 |
| 9 | Effect of Sanhuangyilong decoction plus methotrexate on tumor necrosis factor alpha and interferon gamma in serum and synovial fluid in rheumatoid arthritis patients with symptom pattern of damp heat obstruction显示文摘OBJECTIVE: To investigate the effect of Sanhuangyilong decoction plus methotrexate(MTX) on Interferon gamma(IFN-γ) and tumor necrosis factor alpha(TNF-α) in the serum and synovial fluid of rheumatoid arthritis(RA) patients with damp-heat-obstruction symptom pattern, Sanhuangyilong decoction and the role of TNF-α and IFN-γ in the development of RA.METHODS: RA inpatients with damp-heat-obstruction symptom pattern(partly with knee joint effusion) were selected as the research subjects. Before the treatment, healthy subjects and osteoarthritis(OA) patients with knee joint effusion were assigned to the serum control group and the synovial fluid control group, respectively; during the treatment, RA patients with damp-heat-obstruction symptom pattern were divided into two groups:one is combined group that was administered Sanhuangyilong decoction plus MTX; the other group was MTX group that received MTX only. The expression levels of TNF-α and IFN-γ in the serum and synovial fluid were measured with enzyme-linked immunosorbent assay(ELISA) before and after the treatment, and the peripheral blood levels of erythrocyte sedimentation rate(ESR), C-reactive protein(CRP) and disease activity score in 28 joints(DAS28)were determined.RESULTS: Before treatment, the serum levels of TNF-α and IFN-γ in the RA patients with dampheat-obstruction symptom pattern were higher than those in healthy control group(P < 0.05).The expression levels of TNF-α and IFN-γ in the synovial fluid of the RA patients were higher than those in the serum of the RA patients(P < 0.05). The expression levels of TNF-α and IFN-γ in the synovial fluid of the RA patients were higher than those of the sy-novial fluid of the osteoarthritis patients(P < 0.05).The expression of TNF-α and IFN-γ in the serum and synovial fluid of the RA patients had no correlation with the inflammatory activity index ESR, CRP,or DAS28(P > 0.05). After 2 weeks of treatment, the expression level of TNF-α and IFN-γ in the combined group had increased, although the difference was not statistically significant(P > 0.05); in contrast, ESR, CRP, and DAS28 decreased, and the difference was statistically significant(P < 0.01). After 4 weeks of therapy, TNF-alpha and IFN-γ, ESR,CRP, and DAS28 in the combined group decreased compared with the before-treatment levels(P <0.01). After 2 w of treatment, the differences in the TNF-α and IFN-γ expression levels in the combined group were not statistically significant(P > 0.05)compared with that in the MTX group, although there were statistically significant differences in the ESR, CRP, and DAS28(P < 0.05). After 4 weeks of treatment, differences in TNF-α, IFN-γ, ESR, CRP, and DAS28 in the combined group compared with MTX group were statistically significant(P < 0.01).CONCLUSION: TNF-α and IFN-γ might be involved in the development of RA. The RA patients with damp-heat-obstruction symptom pattern show better benefits from the treatment of Sanhuangyilong decoction plus MTX, and the treatment is superior to that of using MTX only. | Liu Defang Yan Jiao Yun Mingdong Yang Ming Luo Yong Zhang Jun Guo Mingyang Yang Mei Yuan Weili Zou Wei Li Hua Hu Yonghe | 2016 | Journal of Traditional Chinese Medicine2016，36，5： | 4 |
| 10 | Polarization microwave-induced thermoacoustic imaging for quantitative characterization of deep biological tissue microstructures显示文摘Polarization optical imaging can be used to characterize anisotropy in biological tissue microstructures and has been demonstrated to be a powerful tool for clinical diagnosis. However, the approach is limited by an inability to image targets deeper than ~1 mm due to strong optical scattering in biological tissues. As such, we propose a novel polarization microwave-induced thermoacoustic imaging(P-MTAI) technique to noninvasively detect variations in deep tissue by exploiting the thermoacoustic signals induced by four pulsed microwaves of varying polarization orientations. The proposed P-MTAI method overcomes the penetration limits of conventional polarization optical imaging and provides submillimeter resolution over depths of several centimeters. As part of the paper, the structural characteristics of tissues were quantified using a new parameter, the degree of microwave absorption anisotropy. P-MTAI was also applied to the noninvasive detection of morphological changes in cardiomyocytes as they transitioned from ordered to disordered states, providing a potential indication of myocardial infarction. | YUJING LI SHANXIANG ZHANG LINGHUA WU ZHONGWEN CHENG ZHENHUI ZHANG HAOHAO WANG SHUXIANG ZHAO MINGYANG REN SIHUA YANG DA XING HUAN QIN | 2022 | Photonics Research2022，10，5： | 2 |
| 11 | Effect of hand-ear acupuncture on chronic low-back pain: a randomized controlled trial显示文摘OBJECTIVE: To evaluate the effect of hand-ear acupuncture on chronic low-back pain(cLBP).METHODS: This was an open, randomized and controlled trial in The General Hospital of Western Theater Command, Sichuan Province. The trial was registered with ClinicalTrials.gov, NCT02260284. All the 152 participates with cLBP were randomly assigned to hand-ear acupuncture(n = 54), standard acupuncture(n = 50), or usual care groups(n = 48).Eighteen treatments were provided over 7 weeks.Back-related dysfunction and symptom severity were assessed by the Roland-Morris Disability Questionnaire(RMDQ) and the Visual Analogue Scale(VAS), which were collected at baseline, 2 months and 6 months post to the treatment.RESULTS: At 6 months, the RMDQ scores improved by 7.74 points of hand-ear acupuncture group. Significant improvement of VAS and RMDQ was observed in hand-ear acupuncture group(P < 0.001),but no significant changes of RMDQ were observed in both standard acupuncture group and usual care group. We also observed an overall efficacy rate of 88.89% in hand-ear acupuncture group, as evaluated by Diagnosis and Curative Effect Standard for Symptom pattern of Traditional Chinese Medicine, which was much higher than 45.84% in the usual care group(H = 16.000, P < 0.001).CONCLUSION: Both of the hand-ear acupuncture and standard acupuncture modes have beneficial and persistent effectiveness against cLBP compared with the usual care. Furthermore, hand-ear acupuncture is significantly more effective than the standardized acupuncture, especially in the long term. | Luo Yong Yang Min Liu Tao Zhong Xiaolong Tang Wen Guo Mingyang Hu Yonghe | 2019 | Journal of Traditional Chinese Medicine2019，39，4： | 2 |
| 12 | Association of assisted reproductive technology, germline de novo mutations and congenital heart defects in a prospective birth cohort study显示文摘Emerging evidence suggests that children conceived through assisted reproductive technology(ART)have a higher risk of congenital heart defects(CHDs)even when there is no family history.De novo mutation(DNM)is a well-known cause of sporadic congenital diseases;however,whether ART procedures increase the number of germline DNM(gDNM)has not yet been well studied.Here,we performed whole-genome sequencing of 1137 individuals from 160 families conceived through ART and 205 families conceived spontaneously.Children conceived via ART carried 4.59 more gDNMs than children conceived spontaneously,including 332 paternal and 1.26 maternal DNMs,after correcting for parental age at conception,cigarette smoking,alcohol drinking,and exercise behaviors.Paternal DNMs in offspring conceived via ART are characterized by C>T substitutions at CpG sites,which potentially affect protein-coding genes and are significantly associated with the increased risk of CHD.In addition,the accumulation of non-coding functional mutations was independently associated with CHD and 87.9% of the mutations were originated from the father.Among ART offspring,infertility of the father was associated with elevated paternal DNMs;usage of both recombinant and urinary follicle-stimulating hormone and high-dosage human chorionic gonadotropin trigger was associated with an increase of maternal DNMs.In sum,the increased gDNMs in offspring conceived by ART were primarily originated from fathers,indicating that ART itself may not be a major reason for the accumulation of gDNMs.Our findings emphasize the importance of evaluating the germline status of the fathers in families with the use of ART. | Cheng Wang Hong Lv Xiufeng Ling Hong Li Feiyang Diao Juncheng Dai Jiangbo Du Ting Chen Qi Xi Yang Zhao Kun Zhou Bo Xu Xiumei Han Xiaoyu Liu Meijuan Peng Congcong Chen Shiyao Tao Lei Huang Cong Liu Mingyang Wen Yangqian Jiang Tao Jiang Chuncheng Lu Wei Wu Di Wu Minjian Chen Yuan Lin Xuejiang Guo Ran Huo Jiayin Liu Hongxia Ma Guangfu Jin Yankai Xia Jiahao Sha Hongbing Shen Zhibin Hu | 2021 | Cell Research2021，31，8： | 2 |
| 13 | CRISPR/Cas9-mediated targeted mutation reveals a role for AN4 rather than DPL in regulating venation formation in the corolla tube of Petunia hybrida显示文摘Venation is a common anthocyanin pattern displayed in flowers that confers important ornamental traits to plants.An anthocyanin-related R2R3-MYB transcription factor,DPL,has been proposed to regulate corolla tube venation in petunia plants.Here,however,we provide evidence redefining the role of DPL in petunia.A CRISPR/Cas9-mediated mutation of DPL resulted in the absence of the vein-associated anthocyanin pattern above the abaxial surface of the flower bud,but not corolla tube venation,thus indicating that DPL did not regulate the formation of corolla tube venation.Alternately,quantitative real-time PCR analysis demonstrated that the spatiotemporal expression pattern of another R2R3-MYB gene,AN4,coincided with the formation of corolla tube venation in petunia.Furthermore,overexpression of AN4 promoted anthocyanin accumulation by increasing the expression of anthocyanin biosynthesis genes.CRISPR/Cas9-mediated mutation of AN4 led to an absence of corolla tube venation,suggesting that this gene in fact determines this key plant trait.Taken together,the results presented here redefine the prime regulator of corolla tube venation,paving the way for further studies on the molecular mechanisms underlying the various venation patterns in petunia. | Bin Zhang Xiaojing Xu Renwei Huang Sha Yang Mingyang Li Yulong Guo | 2021 | Horticulture Research2021，8，1： | 2 |
| 14 | Detrital Zircon U-Pb Geochronology and Provenance of the Hebukesaier Formation in the Shaerbuerti Mountains,Northern West Junggar:Implication for Devonian Subduction of the Junggar–Balkhash Ocean显示文摘Limited Devonian magmatic record in northern West Junggar leads to contrasting models on its tectonic evolution.In this study,we conducted LA-ICP-MS U-Pb dating on detrital zircons of two sandstones from the Hebukesaier Formation in the Shaerbuerti Mountains.Detrital zircons with oscillatory zoning are characterized by high Th/U(>0.3)and low La/Yb(<0.15),indicating their magmatic origin.The youngest zircon ages of two samples are 402±2 Ma and 406±2 Ma,respectively,suggesting that the Hebukesaier Formation was deposited at the Early Devonian.Detrital zircon age patterns show single peaks(at ca.424 Ma,n=157),which indicates that these clastics were likely proximal accumulation after short distance transportation.Provenance of the Hebukesaier Formation was the Xiemisitai and Shaerbuerti Mountains.Detrital zircon ages range from 481 Ma to 395 Ma,which indicates that there was relatively continuous Early Paleozoic magmatism in the Xiemisitai and Shaerbuerti Mountains since the Early Ordovician.Age spectrums of sampled detrital zircons are distinct from those of Lower Devonian strata either in southern West Junggar or in East Junggar,which implies for individual tectonic evolution of northern West Junggar.We favor that Lower Devonian Hebukesaier Formation was developed in a fore–arc setting due to the northward subduction of the Junggar–Balkhash Ocean. | LIANG Hao CHEN Jiafu MA Xu YANG Hongzhang XIN Mingyang | 2020 | Acta Geologica Sinica(English Edition)2020，94，5： | 2 |
| 15 | Effects of surface roughness on the aerodynamic performance of a high subsonic compressor airfoil at low Reynolds number显示文摘The aerodynamic performance of compressor airfoil is significantly affected by the surface roughness at low Reynolds number(Re).In the present study,numerical simulations have been conducted to investigate the impact of surface roughness on the profile loss of a high subsonic compressor airfoil at Re=1.5×10^(5).Four roughness locations,covering 10%,30%,50%and 100%of the suction surface from the leading edge and seven roughness magnitudes(Ra)ranging from 52 to525 lm were selected.Results showed that the surface roughness mainly determined the loss generation process by influencing the structure of the Laminar Separation Bubble(LSB)and the turbulence level near the wall.For all the roughness locations,the variation trend for the profile loss with the roughness magnitude was similar.In the transitionally rough region,the negative displacement effect of the LSB was suppressed with the increase of roughness magnitude,leading to a maximum decrease of 14.6%,16.04%,16.45%and 10.20%in the profile loss at Ra=157 lm for the four roughness locations,respectively.However,with a further increase of the roughness magnitude in the fully rough region,the stronger turbulent dissipation enhanced the growth rate of the turbulent boundary layer and increased the profile loss instead.By comparison,the leading edge roughness played a dominant role in the boundary layer development and performance variation.To take fully advantage of the surface roughness reducing profile loss at low Re,the effects of roughness on suppressing LSB and inducing strong turbulent dissipation should be balanced effectively. | Mingyang WANG Chengwu YANG Ziliang LI Shengfeng ZHAO Yanfeng ZHANG Xin’gen LU | 2021 | Chinese Journal of Aeronautics2021，34，3： | 2 |
| 16 | Dynamic Response of Falling Liquid Storage Container Under Transient Impact显示文摘The dynamic response performance of a large,cylindrical,fluid-filled steel container under high-speed impact is evaluated through fluid-structure interaction analysis using arbitrary Lagrange-Eulerian(ALE)method.The ALE method is adopted to accurately calculate the structural behavior induced by the internal liquid impact of the container.The stress and strain results obtained from the finite element analysis are in line with the experimental shell impact data.The influences of drop angle,drop height,and flow impact frequency are discussed.Calculation results indicate that the impact stress and damage of the container increase with drop height.However,the amplitude of the oscillation and the impact stress increase when the container and flow impact resonance occur at a certain drop height.The impact stress shows a nonlinear relationship with drop angle. | Yang Xinglin Zhang Guilong Zhang Junmiao Shao Mingyang Cheng Dong | 2018 | Transactions of Nanjing University of Aeronautics and Astronautics2018，35，5： | 2 |
| 17 | Unconventional dual-vacancies in nickel diselenide-graphene nanocomposite for high-efficiency oxygen evolution catalysis显示文摘Although nickel-based catalysts display good catalytic capability and excellent corrosion resistance under alkaline electrolytes for water splitting,it is still imperative to enhance their activity for real device applications.Herein,we decorated Ni0.85Se hollow nanospheres onto reduced graphene oxide(RGO)through a hydrothermal route,then annealed this composite at different temperatures(400℃,NiSe2-400 and 450℃,NiSe2-450)under argon atmosphere,yielding a kind of NiSe2/RGO composite catalysts.Positron annihilation spectra revealed two types of vacancies formed in this composite catalyst.We found that the NiSe2-400 catalyst with dual Ni-Se vacancies is able to catalyze the oxygen evolution reaction(OER)efficiently,needing a mere 241 mV overpotential at 10 mA·cm−2.In addition,this catalyst exhibits outstanding stability.Computational studies show favorable energy barrier on NiSe2-400,enabling moderate OH−adsorption and O2 desorption,which leads to the enhanced energetics for OER. | Pengkun Wei Zewei Hao Yang Yang Mingyang Liu Haijun Zhang Min-Rui Gao Shu-Hong Yu | 2020 | Nano Research2020，13，12： | 2 |
| 18 | MOF-derived Co_(9)S_(8) nano-flower cluster array modified separator towards superior lithium sulfur battery显示文摘Lithium sulfur batteries with high energy density are thought to be the most potential energy storage technology that can be commercialized.However,the shuttle effect of polysulfides deteriorates its electrochemical performance.Herein,a novel Co_(9)S_(8)nanostructure derived from metal organic framework material(MOF)was explored by simple liquid phase reaction and heat vulcanization of2-methylimidazole and Co(NO_(3))_(2)·6 H_(2)O on the surface of the original PP separator.The Co_(9)S_(8)nano-flower cluster array wall was vertically and closely arranged with the thickness of 200 nm,and the polysulfide can be adsorbed by its physical and chemical action to slow down the'shuttle effect'.It is found that the cell with the modified separator can achieve an ideal discharge capacity of about 600 mAh/g at 1 C.The specific capacity is maintained at 500 mAh/g after 200 cycles,with only 0.11%of capacity decay per cycle.It provides a new way for the utilization of MOF material derivatives to modify the separator in order to improve the electrochemical performance of lithium-sulfur batteries. | Qi Wang Hanqing Zhao Boya Li Chenhui Yang Mingyang Li Yanan Li Peng Han Miaomiao Wu Tengyu Li Ruiping Liu | 2021 | Chinese Chemical Letters2021，32，3： | 2 |
| 19 | Risk factors associated with hemorrhagic cystitis after allogeneic hematopoietic stem cell transplantation显示文摘Hemorrhagic cystitis(HC)is a common complication of allogeneic hematopoietic stem cell transplantation(HSCT).The incidence is about 7%to 68%,and some patients have to suffer a long period of frequent,urgent,and painful urination,which brings great pain.This study aimed to analyze risk factors of HC and its effect on patient survival.We collected the medical records of 859 patients who underwent HSCT at our hospital between August 2016 and August 2020.Patients with and without HC were matched using propensity score matching at a 1:1 ratio based on sex,age,and diagnosis,and logistic regression analyses were used to identify factors associated with HC.We used Kaplan–Meier curves to analyze the survival rates of patients in the HC and non-HC groups.We also analyzed the relationship between BK viral load and the occurrence of HC using receiver operating characteristic curve(ROC)analysis.After propensity score matching,there were 131 patients each in the HC and non-HC groups.In the HC group,89 patients(67.9%)had mild HC(stage II°)and 43(32.1%)had severe HC(stage III–IV).The median interval between stem cell transplantation and HC development was 31(3–244)days.Univariate analysis indicated that donor age,hematopoietic stem cell source,HLA,acute graft-versus-host disease,busulfan,anti-thymocyte globulin(ATG),total body irradiation,cytomegalovirus(CMV)(urine),and BK polyomavirus(BKV)(urine)were significantly associated with HC.ATG,CMV(urine),and BKV(urine)were independent risk factors for HC based on the multivariate analysis.The Kaplan–Meier survival analysis showed no significant difference between the HC and non-HC groups(P=0.14).The 1-and 2-year survival rates in the HC group were 78.4%and 69.6%,respectively,and the corresponding rates in the non-HC group were 84.4%and 80.7%,respectively.ROC analysis indicated that a urine BKV load of 1×10^(7) copies/mL was able to stratify the risk of HC.In conclusion,when the BKV load is>1×10^(7),we needtobe aware of the potential for the development of HC. | Biao Shen Yueshen Ma Haixiao Zhang Mingyang Wang Jia Liu Jiaxin Cao Wenwen Guo Dan Feng Donglin Yang Rongli Zhang Xin Chen Qiaoling Ma Weihua Zhai Sizhou Feng Mingzhe Han Aiming Pang Erlie Jiang 无 | 2022 | Blood Science2022，4，2： | 2 |
| 20 | In situ assembly of magnetic nanocrystals/graphene oxide nanosheets on tumor cells enables efficient cancer therapy显示文摘Owing to the stimulus-responsive and dynamic properties,magnetism-driven assembly of building blocks to form ordered structures is always a marvelous topic.While abundant magnetic assemblies have been developed in ideal physical and chemical conditions,it remains a challenge to realize magnetic assembly in complicated biological systems.Herein,we report a kind of biomacromolecule-modified magnetic nanosheets,which are mainly composed of superparamagnetic graphene oxide(Y-Fe2O3@GO),the tumor-targeting protein transferrin(TF),and the mitochondrion-targeting peptide(MitP).Such large-size nanosheets(0.5-1μm),noted as L-Fe2O3@GO-MitP-TF,can successfully in s itu assemble on the surface of tumor cells in a size-dependent and tumor cell-specific way,leading to severe inhibition of nutrient uptake for the tumor cells.More significantly,the nanostructures could efficiently confine the tumor cells,preventing both invasion and metastasis of tumor cells both in vitro and in vivo.Moreover,the 2D assemblies could remarkably disrupt the mitochondria and induce apoptosis,remarkably eradicating tumors under near-infrared(NIR)irradiation.This study sheds light on the development of new nano-systems for efficient cancer therapy and other biomedical applications. | Mingyang Liu Yang Lu Qilin Yu Shu-Hong Yu | 2020 | Nano Research2020，13，4： | 1 |
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