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您的检索式：作者名="Mihai G.Netea"
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| 1 | Engagement of fatty acids with toll‐like receptor 2 drives interleukin‐1β production via the ASC/caspase 1 pathway in monosodium urate monohydrate crystal–induced gouty arthritis显示文摘 | Leo A. B.Joosten Mihai G.Netea EleniMylona Marije I.Koenders R. K. SubbaraoMalireddi MarijeOosting RinkeStienstra Frank L.van de Veerdonk Anton F.Stalenhoef Evangelos J.Giamarellos‐Bourboulis Thirumala‐DeviKanneganti Jos W. M.van der Meer | 2010 | Arthritis & Rheumatism2010，，11： | 1 |
| 2 | 2岁以下新型冠状病毒肺炎患儿快速康复可能与频繁疫苗接种有关显示文摘新型冠状病毒肺炎(COVID-19)的重症和死亡与年龄有关,儿童感染者很少重症和死亡,其机制尚不完全清楚.我们回顾性地研究了湖北省十堰市太和医院就诊的186例新冠肺炎患者,发现10岁以下患儿主要临床表现均为轻症,而非成人的严重病症.进一步年龄分层分析发现, 2岁以下患儿更不易合并肺炎支原体共感染,康复时间平均缩短6 d,治疗后淋巴细胞计数回升更明显.患儿康复时间缩短与中西药治疗没有显著关联性,而与其频繁接种疫苗有关.因此, 2岁以下频繁接种疫苗可能激活免疫系统,对新型冠状病毒感染及肺炎支原体共感染具有更强的免疫力. | 邱力 张成东 吴俊波 罗杰 Mihai G.Netea 骆志国 冷启彬 | 2020 | Science Bulletin2020，65，24： | 1 |
| 3 | Genetic regulators of cytokine responses upon BCG vaccination in children from West Africa显示文摘Genetic variation is a key factor influencing cytokine production capacity,but which genetic loci regulate cytokine production before and after vaccination,particularly in African population is unknown.Here,we aimed to identify single-nucleotide polymorphisms(SNPs)controlling cytokine responses after microbial stimulation in infants of West-African ancestry,comprising of low-birth-weight neonates randomized to bacillus Calmette-Gue rin(BCG)vaccine-at-birth or to the usual delayed BCG.Genome-wide cytokine cytokine quantitative trait loci(cQTL)mapping revealed 12 independent loci,of which the LINC01082-LINC00917 locus influenced more than half of the cytokine-stimulation pairs assessed.Furthermore,nine distinct cQTLs were found among infants randomized to BCG.Functional validation confirmed that several complement genes affect cytokine response after BCG vaccination.We observed a limited overlap of common cQTLs between the West-African infants and cohorts of Western European individuals.These data reveal strong population-specific genetic effects on cytokine production and may indicate new opportunities for therapeutic intervention and vaccine development in African populations. | Collins K.Boahen S.J.C.F.M.Moorlag Kristoffer Jarlov Jensen Vasiliki Matzaraki Stephanie Fanucchi Ivan Monteiro Charlotte de Bree Ezio T.Fok Musa Mhlanga Leo A.B.Joosten Peter Aaby Christine Stabell Benn Mihai G.Netea Vinod Kumar | 2023 | Journal of Genetics and Genomics2023，50，6： | 0 |
| 4 | Hematopoietic memory of severe COVID-19 infection显示文摘A new study describes that individuals who recovered from severe coronavirus disease-19(COVID-19)exhibit long-term epigenetic changes in their hematopoietic stem and progenitor cells,which are subsequently conveyed to circulating progeny myeloid cells.This epigenetic memory of hematopoietic cells is partly mediated by IL-6 induction in the acute phase of the infection and may account for the long-term altered myeloid cell function after COVID-19. | Anaisa V.Ferreira Mihai G.Netea | 2024 | Cell Research2024，34，3： | 0 |
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