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| 1 | Nature:骨髓微环境发生突变可导致造血干细胞异常显示文摘白血病骨髓微环境中支持血液发育的某些DNA突变可以驱动周围造血干细胞形成白血病,来自艾默里大学温希普癌症研究所和亚特兰大儿童健康中心的研究人员在国际学术期刊Nature上公布了他们的最新研究进展。许多致癌突变都作用于细胞自身。让细胞自身生长更快。相比之下,努南综合征小鼠模型上可以观察到间接的邻近细胞效应,努南综合征是一种能够增加白血病患病风险的遗传紊乱。 | Lei Dong, Wen-Mei Yu, Hong Zheng, Melinda Pauly, Muxiang Zhou Cheng-Kui Qu Mignon L. Loh Silvia T. Bunting Gang Huang Hal E. Broxmeyer David T. Scadden | 2016 | 现代生物医学进展2016，16，35： | 18 |
| 2 | Whey protein: The “whey” forward for treatment of type 2 diabetes?显示文摘A cost-effective nutritional approach to improve postprandial glycaemia is attractive considering the rising burden of diabetes throughout the world. Whey protein, a by-product of the cheese-making process, can be used to manipulate gut function in order to slow gastric emptying and stimulate incretin hormone secretion, thereby attenuating postprandial glycaemic excursions. The function of the gastrointestinal tract plays a pivotal role in glucose homeostasis, particularly during the postprandial period, and this review will discuss the mechanisms by which whey protein slows gastric emptying and stimulates release of gut peptides, including the incretins. Whey protein is also a rich source of amino acids, and these can directly stimulate beta cells to secrete insulin, which contributes to the reduction in postprandial glycaemia. Appetite is suppressed with consumption of whey, due to its effects on the gut-brain axis and the hypothalamus. These properties of whey protein suggest its potential in the management of type 2 diabetes. However, the optimal dose and timing of whey protein ingestion are yet to be defined, and studies are required to examine the long-term benefits of whey consumption for overall glycaemic control. | Linda E Mignone Tongzhi Wu Michael Horowitz Christopher K Rayner | 2015 | World Journal of Diabetes2015，6，14： | 2 |
| 3 | Genetic analysis of a selection experiment on the growth curve of chickens显示文摘 | Mignon G S Beaumont C Ricard F H | 2001 | Poultry Science2001，80，7： | 1 |
| 4 | Expression of the putative stem cell marker Musashi‐1 in Barrett’s esophagus and esophageal adenocarcinoma显示文摘 | Y. V.Bobryshev A. K.Freeman N. K.Botelho D.Tran A. J. M.Levert‐Mignon R. V. N.Lord | 2010 | Diseases of the Esophagus2010，，7： | 1 |
| 5 | CD3-OFDM:a novel demodulation scheme for fixed and mobile receivers显示文摘 | MIGNONE V MORRELLO A | 1996 | IEEE Transactions on Communication1996，44，9： | 1 |
| 6 | AnAnalytical Model for the Determination of Optimal Output Reflectivity and Fiber Length in Erbium-Doped Fiber Lasers显示文摘 | Mignon M Desurvire E | 1992 | IEEE Photon Technol Lett 41992，，： | 1 |
| 7 | Oil prices and economic activity : an asymmetric cointegration approach显示文摘 | Lardic S Mignon V | 2008 | Energy Economics2008，30，3： | 1 |
| 8 | Hepatic response to sep- sis: interaction between coagulation and inflammatory processes 显示文摘 | Dhainaut JF Matin N Mignon A | 2001 | Crit Care Med2001，29，7： | 1 |
| 9 | Imaging features of gastric stromal tumors : radiologic-pathologic correlation : report of 4 cases 显示文摘 | Mignon F Julie C Lzzillo R | 2000 | J Radiol2000，81，8： | 1 |
| 10 | Analysis of discrete-time piecewise affine and hybrid systems 显示文摘 | FERRARI-TRECATE G CUZZOLA F MIGNONE D | 2002 | Automatica2002，31，12： | 1 |
| 11 | Air interfaces for satellite based digital TV broadcasting in the railway environment显示文摘 | Scalise S Mura R and Mignone V | 2006 | IEEE Transactions on Broadcasting2006，52，2： | 1 |
| 12 | On the impact of inflation on output growth:Does the level of inflation matter? 显示文摘 | Lopez-Villavicencio A Mignon V | 2011 | Journal of Macroeconomics2011，33，3： | 1 |
| 13 | Nestin expression in hair follicle sheath progenitor cells显示文摘 | Li LG Mignone J Yang M | 2003 | Proc Natl Acad Sci U S A2003，100，： | 1 |
| 14 | Neural stem andprogenitor cells in nestin-GFP transgenic mice显示文摘 | Mignone JL Kukekov V Chiang AS | 2004 | J Comp Neurol2004，469，3： | 1 |
| 15 | The effects of a monoclonal antibody to interferon-gamma on experimental autoimmune thyroiditis (EAT):prevention of disease and decrease of EAT-specific T cells显示文摘 | Tang H Mignon Godefroy K Meroni P L | 1993 | Eur J Immunol1993，23，1： | 1 |
| 16 | CD3-OFDM: A novel demodulation scheme for fixed and mobile receivers 显示文摘 | Morello A | 1996 | IEEE Trans on com1996，44，： | 1 |
| 17 | Mapping of the galectin-3 gene (LGALS3) to human chromosome 14 at region 14q21-22显示文摘 | Raimnnd J Zimonjie DB Mignon C | 1997 | Mamm Genome1997，8，9： | 1 |
| 18 | Genetic analysis of a selection experiment on the growth curve of chickens显示文摘 | Mignon G S Beaumont C Ricard F H | 2001 | Poultry Science2001，80，7： | 1 |
| 19 | A new sliding-mode control with fuzzy boundary layer 显示文摘 | LEE H KIM E KANG H J MIGNON P | 2001 | Fuzzy Sets and Systems2001，120，1： | 1 |
| 20 | Imaging of gastrointestinal stromal tumors:radiologic-pathologic correlation,report of 4 cases显示文摘 | Mignon F Julie C Lzzillo R | 2000 | J Radiol2000，81，： | 1 |
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