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| 1 | Functionalization of Single- and Multi-Walled Carbon Nanotubes with Cationic Amphiphiles for Plasmid DNA Complexation and Transfection显示文摘The possibility of delivering DNA effi ciently to cells represents a crucial issue for the treatment of both genetic and acquired diseases.However,even although the effi ciency of non-viral transfection systems has improved in the last decade,none have yet proven to be suffi ciently effective in vivo.We report herein our results on the functionalization of single-walled carbon nanotubes(SWNT)and multi-walled carbon nanotubes(MWNT)by two cationic amphiphiles(lipid RPR120535 and pyrenyl polyamine),their use for the complexation of plasmid DNA,and their efficiency in transfecting cells in vitro.The experiments have shown that the efficiency of transfection is higher when using SWNT instead of MWNT,and that transfection effi ciency is similar or slightly higher when using nanoplexes(SWNT/lipid RPR120535/DNA)instead of lipoplexes(lipid RPR120535/DNA)and several orders of magnitude higher than that of naked DNA.This study therefore shows both that the transfection is better when using SWNTs and that it is dependent on the nature of the amphiphilic molecules adsorbed on the nanotubes. | Cyrille Richard Nathalie Mignet Céline Largeau Virginie Escriou Michel Bessodes Daniel Scherman | 2009 | Nano Research2009，2，8： | 3 |
| 2 | Cationic lipids for transfection显示文摘 | Nicolazzi C Garinot M Mignet N | | 0，，： | 1 |
| 3 | Anionic pH-sensitive pegylated lipoplexes to deliver DNA to tumors显示文摘 | Mignet N Richard C Scherman D | 2008 | Int J Pharm2008，361，12： | 1 |
| 4 | Studying the XML Web:gathering statistics from an XML sample显示文摘 | Barbosa D Mignet L Veltri P | 2005 | World Wide Web:Internet and Web Information Systems2005，8，4： | 1 |
| 5 | Amphiphilic polyether branched molecules to increase the circulalion time of cationic particles 显示文摘 | GAR1NOT M MIGNET N LARGEAU C | 2007 | Bioorg Med Chem2007，15，9： | 1 |
| 6 | Design, synthesis, and evaluation of gadolinium cationic lipids as tools for biodistribution studies of gene delivery complexes显示文摘 | LECLERCQ F COHEN OHANA M MIGNET N | 2003 | Bioeonjugate Chemistry2003，14，1： | 1 |
| 7 | Design,synthesis,and evaluation of gadolinium cationic lipids as tools for biodistribution studies of gene delivery complexes显示文摘 | Leclercq F Cohen-Ohana M Mignet N | 2003 | Bioconjugate Chem2003，14，1： | 1 |
| 8 | Design, synthesis, and evaluation of gadolinium cationic lipids as tools for biodistribution studies of gene delivery complexes显示文摘 | Leclercq F Cohen ~ Ohana M Mignet N | 2003 | Bioconiug Chem2003，14，1： | 1 |
| 9 | Proteomic analysis of malignant B-cell derived microparticles reveals CD148 as a potentially usefull antigenic biomarker for mantle cell lymphoma diagnosis显示文摘 | Mignet L Bechaad G Fornrcker L | 2009 | J Proteome Res2009，8，7： | 1 |
| 10 | Proteomic analysis of malignant B-cell derived microparticles reveals C D 148 as a potentially useful antigenic biomarker for mantle cell lymphoma diagnosis 显示文摘 | Mignet L Fomecker L Zink E | 2009 | J Proteome Res2009，8，7： | 1 |
| 11 | 查看详情显示文摘 | Chaumet-Riffaud P Martinez-Duncker I Marry A.L Richard C. Prigent A. Moati F. Sarda-Mantel L. Scherman D. Michel Bessodes M. Nathalie Mignet N | | 0，，： | 1 |
| 12 | Ultrasound and mi- crobubble-assisted gene delivery: recent advances and ongoing challenges 显示文摘 | Delalande A Postema M Mignet N | 2012 | Ther Deliv2012，3，10： | 1 |
| 13 | Studying the XML web:Gathering statistics from an XML sample显示文摘 | Barbosa D Mignet L Veltri P | 2006 | World Wide Web2006，9，2： | 1 |
| 14 | Discovery and identification of potential biomarkers in a prospective study of chronic lymphoid malignancies using SELDI-TOF-MS显示文摘 | Mignet L Bognmil R Decloquement P | | 0，，09： | 1 |
| 15 | Studying the XML Web: gathering statistics from an XML sample显示文摘 | Bardosa D Mignet L Veltri P | 2006 | World Wide Web2006，9，2： | 1 |
| 16 | XML Repository and Active Views Demonstration 显示文摘 | Serge 'Abiteboul Vincent Aguilera Sebastien Ailleret Bernd Amann Sophie Chet Brendan Hills Frederic Hubert Jean - Claude Mamou Amelie Marian Laurent Mignet Tova Milo Cassio Souza dos Santos xruno Tessier Anne- Marie Vercoustre | 1999 | VLDB1999，，： | 1 |
| 17 | Amphiphilic polyether branched molecules to increase the circulation time of cationic particles显示文摘 | GARINOT M MIGNET N LARGEAU C | 2007 | Bioorg Med Chem2007，15，9： | 1 |
| 18 | Ultrasound and microbubble-assisted gene delivery: recent advances and ongoing challenges 显示文摘 | Delalande A Postema M Mignet N | 2012 | Ther Deliv2012，3，10： | 1 |
| 19 | Anionic pH-sensitive pegylated lipoplexes to deliver DNA to tumors 显示文摘 | Mignet N Richard C Scherman D | 2008 | Int J Pharm2008，361，12： | 1 |
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