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| 1 | Diagnostic aids for detection of oral precancerous conditions显示文摘Oral cancer has a tendency to be detected at late stage which is detrimental to the patients because of its high mortality and morbidity rates. Early detection of oral cancer is therefore important to reduce the burden of this devastating disease. In this review article, the most common oral precancerous lesions are discussed and the importance of early diagnosis is emphasized. In addition, the most common non-invasive oral cancer devices that can aid the general practitioners in early diagnosis are also discussed. | Diana V Messadi | 2013 | International Journal of Oral Science2013，5，2： | 15 |
| 2 | The clinical effectiveness of reflectance optical spectroscopy for the in vivo diagnosis of oral lesions显示文摘Optical spectroscopy devices are being developed and tested for the screening and diagnosis of oral precancer and cancer lesions. This study reports a device that uses white light for detection of suspicious lesions and green–amber light at 545 nm that detect tissue vascularity on patients with several suspicious oral lesions. The clinical grading of vascularity was compared to the histological grading of the biopsied lesions using specific biomarkers. Such a device, in the hands of dentists and other health professionals, could greatly increase the number of oral cancerous lesions detected in early phase. The purpose of this study is to correlate the clinical grading of tissue vascularity in several oral suspicious lesions using the IdentafiH system with the histological grading of the biopsied lesions using specific vascular markers. Twenty-one patients with various oral lesions were enrolled in the study. The lesions were visualized using IdentafiH device with white light illumination, followed by visualization of tissue autofluorescence and tissue reflectance. Tissue biopsied was obtained from the all lesions and both histopathological and immunohistochemical studies using a vascular endothelial biomarker(CD34) were performed on these tissue samples. The clinical vascular grading using the green–amber light at 545 nm and the expression pattern and intensity of staining for CD34 in the different biopsies varied depending on lesions, grading ranged from 1 to3. The increase in vascularity was observed in abnormal tissues when compared to normal mucosa, but this increase was not limited to carcinoma only as hyperkeratosis and other oral diseases, such as lichen planus, also showed increase in vascularity. Optical spectroscopy is a promising technology for the detection of oral mucosal abnormalities; however, further investigations with a larger population group is required to evaluate the usefulness of these devices in differentiating benign lesions from potentially malignant lesions. | Diana V Messadi Fariba S Younai Hong-Hu Liu Gao Guo Cun-Yu Wang | 2014 | International Journal of Oral Science2014，6，3： | 2 |
| 3 | Activation of NF kappaB signal pathways in keloid fibroblasts 显示文摘 | Messadi DV Doung HS Zhang Q | 2004 | Arch Dermatol Res2004，296，3： | 1 |
| 4 | Hypoxia-induced HIF-1 alpha accumulation is augmented in a co-culture of keloid fibroblasts and human mast cells: involvement of ERK1/2 and PI-3K/Akt 显示文摘 | Zhang Q Oh CK Messadi DV | 2006 | Exp Cell Res2006，312，2： | 1 |
| 5 | Predictive control of a chaotic permanent magnet synchronous generator in a wind turbine system显示文摘This paper investigates how to address the chaos problem in a permanent magnet synchronous generator(PMSG)in a wind turbine system.Predictive control approach is proposed to suppress chaotic behavior and make operating stable;the advantage of this method is that it can only be applied to one state of the wind turbine system.The use of the genetic algorithms to estimate the optimal parameter values of the wind turbine leads to maximization of the power generation.Moreover,some simulation results are included to visualize the effectiveness and robustness of the proposed method. | Manal Messadi Adel Mellit Karim Kemih Malek Ghanes | 2015 | Chinese Physics B2015，24，1： | 1 |
| 6 | Halitosis 显示文摘 | Messadi DV Younai FS | 2003 | Dermatol Clin2003，21，1： | 1 |
| 7 | Oral lichen planus is a unique disease model for studying chronic inflammation and oral cancer显示文摘 | Liu Y Messadi D V Wu H | 2010 | Med Hypotheses2010，75，6： | 1 |
| 8 | Aphthous ulcers显示文摘 | Messadi DV Younai F | 2010 | Dermato! T- her2010，23，3： | 1 |
| 9 | CD44 and hyaluronan expression in human cutaneous scar fibroblasts显示文摘 | MESSADI DV BERTOLAMI CN | 1993 | Am J Pathol1993，142，： | 1 |
| 10 | Association between antibiotic use and changes in susceptibility patterns of Pseudomonas aernginosa in an intensive care burn unit:A 5-year study,20O0-2004显示文摘 | Messadi A A Lamia T Kamel B | 2008 | Bums2008，10，3： | 1 |
| 11 | Analysis of the population structure of Mycobacterium tuberculosis in Ethiopia, Tunisia, and the Netherlands, usefulness of DNA typing for global tuberculosis epidemiology 显示文摘 | Hermans PW Messadi F Guebrexabher H | 1995 | Infect Dis1995，171，6： | 1 |
| 12 | I-ILA class Ⅱ alleles and mul- tiple sclerosis in Tunisian patients显示文摘 | Messadi A Najiba F M Ouerlaani S | 2010 | Clin Neural Neurosurg2010，112，10： | 1 |
| 13 | Geographic distribution of MERS coronavirus among dromedary camels, Africa显示文摘 | Reusken CB Messadi L Feyisa A | 2014 | Emerg Infect Dis2014，20，8： | 1 |
| 14 | Detecting and treating oral malodor显示文摘 | Clark G Nachnani S Messadi D | 1997 | J Calif Dent Assoc1997，25，2： | 1 |
| 15 | Cardioprotective effect of VEGF and venom VEGF-like protein in acute myocardial isehemia in mice: effect on mitoehondrial function显示文摘 | Messadi E Aloui Z Belaidi E | 2014 | J Cardiovase Pharmaeol2014，63，3： | 1 |
| 16 | Task - specific ionic liquid with coordinating anion for heavy metal ion extraction : Cation exchange versus ion - pair extraction 显示文摘 | Messadi A Mohamadou A Boudesocque S | 2013 | Separation and Purification Technology2013，107，： | 1 |
| 17 | Activation of NF-κB signal pathways in keloid fibroblasts显示文摘 | Diana V Messadi Hai S | 2004 | Arch Dermatol Res2004，296，11： | 1 |
| 18 | Aphthousulcers显示文摘 | Messadi DV Yotmai F | 2010 | Dermatoi Ther2010，23，3： | 1 |
| 19 | Discussion and citation in autologous facial fat transplantation: Improved graft maintenance by microbead bioactivation 显示文摘 | MESSADI D SHETrFy V SKETRIL DS | 1992 | J Oral Maxillofac Surg1992，50，5： | 1 |
| 20 | Aphthous ulcers 显示文摘 | Messadi DV Younai F | 2010 | Dermatol Ther2010，23，3： | 1 |
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