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1口腔潜在恶性病变癌变的早期无创检查方法显示文摘口腔潜在恶性病变(oral potential malignant disorders,OPMDs)是一类发生在口腔黏膜、具有癌变潜能的疾病总称。OPMDs癌变率约为5%~18%。为阻断癌变进程,提高患者的生存质量,医生对其进行早期筛查诊断。无/微创筛查技术用于OPMD癌变的早期诊断,对患者创伤小,易被患者接受。本文即对近年常用早期诊断OPMD癌变的无/微创筛查技术进行综述。梁甲武 卫明慧 刘青 2018实用口腔医学杂志2018,34,4:4
2Diagnostic aids in detection of oral cancer: An update显示文摘Oral cancer is the sixth most common malignancy with almost 500000 new cases reported worldwide annually. The diagnosis of oral cancer at an early stage has a good prognosis as the survival rate is high(around 80%). However, the majority of oral cancer cases are diagnosed at a later stage with a considerablypoor 5-year survival rate of 50% according to World Health Organization statistics. Thus, an effective management strategy for oral cancer will depend on its early identification and intervention which would pave the way for superior prognosis. Despite the obvious advantage of earlier diagnosis of oral cancer, no approach has yet proven to be a reliably successful in diagnosis of oral cancer at an early stage. Currently; the primary line of screening of oral cancer is performed by visual inspection, which is a subjective examination. Among the screening tests or diagnostic aids now available for oral cancer, few(toluidine blue, brush biopsy, salivary and serum bio-markers) have been utilised and studied for many years while others have recently become commercially available. The authors in the present article review all the modalities of screening aids used in oral cancer detection and provide an update on the latest screening tools used in oral cancer detection.Gaurav Sharma 2015World Journal of Stomatology2015,4,3:0
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