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| 1 | Endoscopic stenting for inoperable malignant biliary obstruction: A systematic review and meta-analysis显示文摘AIM: To analyze through meta-analyses the benefits of two types of stents in the inoperable malignant biliary obstruction.METHODS: A systematic review of randomized clinical trials(RCT) was conducted, with the last update on March 2015, using EMBASE, CINAHL(EBSCO), MEDLINE, LILACS/CENTRAL(BVS), SCOPUS, CAPES(Brazil), and gray literature. Information of the selected studies was extracted in sight of six outcomes: primarily regarding dysfunction, complication and reintervention rates; and secondarily costs, survival, and patency time. The data about characteristics of trial participants, inclusion and exclusion criteria and types of stents were also extracted. The bias was mainly assessed through the JADAD scale. This meta-analysis was registered in the PROSPERO database by the number CRD42014015078. The analysis of the absolute risk of the outcomes was performed using the software Rev Man, by computing risk differences(RD) of dichotomous variables and mean differences(MD) of continuous variables. Data on RD and MD for each primary outcome were calculated using the MantelHaenszel test and inconsistency was qualified and reported in χ2 and the Higgins method(I2). Sensitivity analysis was performed when heterogeneity was higher than 50%, a subsequent assay was done and other findings were compiled. Student's t-test was used for the comparison of weighted arithmetic means regarding secondary outcomes.RESULTS: Initial searching identified 3660 studies; 3539 were excluded through title, repetition, and/or abstract, while 121 studies were fully assessed and were excluded mainly because they did not compare self-expanding metal stents(SEMS) and plastic stents(PS), leading to thirteen RCT selected, with 13 articles and 1133 subjects meta-analyzed. The mean age was 69.5 years old, that were affected mostly by bile duct(proximal) and pancreatic tumors(distal). The preferred SEMS diameter used was the 10 mm(30 Fr) and the preferred PS diameter used was 10 Fr. In the metaanalysis, SEMS had lower overall stent dysfunction compared to PS(21.6% vs 46.8%, P < 0.00001) and fewer re-interventions(21.6% vs 56.6%, P < 0.00001), with no difference in complications(13.7% vs 15.9%, P = 0.16). In the secondary analysis, the mean survival rate was higher in the SEMS group(182 d vs 150 d, P < 0.0001), with a higher patency period(250 d vs 124 d, P < 0.0001) and a lower cost per patient(4193.98 vs 4728.65 Euros, P < 0.0985).CONCLUSION: SEMS are associated with lower stent dysfunction, lower re-intervention rates, better survival, and higher patency time. Complications and costs showed no difference. | Leonardo Zorrón Pu Eduardo Guimaraes Hourneaux de Moura Wanderley Marques Bernardo Felipe Iankelevich Baracat Ernesto Quaresma Mendonca AndréKondo Gustavo Oliveira Luz Carlos Kiyoshi Furuya Júnior Everson Luiz de Almeida Artifon | 2015 | World Journal of Gastroenterology2015，21，47： | 10 |
| 2 | Pierre robin sequence 显示文摘 | Gangopadhyay N Mendonca DA Woo AS | 2012 | Semin PIast Surg2012，26，2： | 1 |
| 3 | Modeling of droplet dynamic and thermal behavior during spray deposition 显示文摘 | MAHESH N S MENDONCA J MURALIDHARA M K | 2003 | Indian Academy of Sciences2003，26，3： | 1 |
| 4 | Predictors of tissue-type plasminogen activator nonresponders according to location of vessel occlusion显示文摘 | Mendonca N Rodriguez-Luna D Rubiera M | 2012 | Stroke2012，43，： | 1 |
| 5 | Modeling of droplet dynamic and thermal behavior during spray deposition 显示文摘 | Mendonca Johnson Mahesh N S Muralidhara M K | 2003 | Mater Science Bull2003，26，3： | 1 |
| 6 | Predictors of tissue-type plas- minogen activator nonresponders accord- ing to location ofvessel occlusion 显示文摘 | Mendonca N Rodriguez-Luna D Rubi- era M | 2012 | Stroke2012，43，2： | 1 |
| 7 | Client-side selection of replicated web Services:An empirical assessment显示文摘 | Mendonca N C Silva J A F Anido R O | 2008 | The Journal of Systems and Software2008，81，8： | 1 |
| 8 | Epi- demiology and predictors of a poor outcome in elderly pa- tients with candidemia 显示文摘 | Guimaraes T Nucci M Mendonca JS Martinez R Brito LR Silva N Moretti ML Salomfio R Colombo AL | 2012 | Int J Infect Dis2012，16，6： | 1 |
| 9 | Su-pervised weighting - online learning algorithm for short - termtraffic flow prediction 显示文摘 | JEONG Y S BYON Y J MENDONCA C N EASA S M | 2013 | IEEE Transactions on IntelligentTransportation Systems2013，14，4： | 1 |
| 10 | Association between antimicrobial resistance and virulence in Escherichia coli显示文摘 | Da Silva GJ Mendonca N | 2012 | Virulence2012，3，1： | 1 |
| 11 | Improved multi-plex PCR method for the rapid detection of beta-lactamasegenes in Escherichia coli of animal origin显示文摘 | Pomba C Mendonca N Costa M | 2006 | Diagn Micro-biol Infect Dis2006，56，1： | 1 |
| 12 | First report of Stagonosporiopsis cucurbitacearum causing fruit rot of Luffa cylindrica in Brazil 显示文摘 | Silva M Freitas N M Mendonca H L | 2013 | Plant Disease2013，97，8： | 1 |
| 13 | Ethical Leader- ship in Three Dimensions 显示文摘 | KANUNGO R N MENDONCA M | 1998 | Journal of Human Values1998，，： | 1 |
| 14 | New guidelines for the clinical management of febrile neutropenia and sepsis in pediatric oncology patients显示文摘 | Mendes AV Sapolnik R Mendonca N | | 0，，2： | 1 |
| 15 | Microarray Evaluation of Antimicrobial Resistance and Virulence of Escherichia coli Isolates from Portuguese Poultry显示文摘 | Mendonca N Figueiredo R Mendes C | 2016 | J Antibiot2016，5，1： | 1 |
| 16 | Nonlinear absorption dynamics in tetrapyridyl metalloporphyrins显示文摘 | Neto N M B Boni L D Mendonca C R | 2005 | J Phys Chem B2005，109，17： | 1 |
| 17 | New guidelines for the clinical management of febrile neutropenia and sepsis in pediatric oncology patients 显示文摘 | Mendes AV Sapolnik R Mendonca N | 2007 | J Pediatr2007，83，2： | 1 |
| 18 | Diffusion weighted MRI in two cases of familial Creutzfeldt-Jakob disease 显示文摘 | Nitrini R Mendonca RA Huang N | 2001 | J Neurol Sci2001，184，2： | 1 |
| 19 | Rapid DNA extraction protocol from soil for polymerasechain reaction mediated amplification 显示文摘 | Smalla K Cresswell N Mendonca Hagler L C | 1993 | J Appl Microbi-ol1993，74，1： | 1 |
| 20 | Spread of extended-spectrum β-lactamase CTX-M-producing Escherichia coli clinical isolates in community and nosocomial environments in Portugal显示文摘 | MENDONCA N LEITAO J MANAGEIRO V | 2007 | Antimicrob Agents Chemother2007，51，6： | 1 |
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