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| 1 | Middle East respiratory syndrome coronavirus disease is rare in children: An update from Saudi Arabia显示文摘AIM To summarize the reported Middle East respiratory syndrome-coronavirus(MERS-Co V) cases, the associated clinical presentations and the outcomes. METHODS We searched the Saudi Ministry of Health website, the World Health Organization website, and the Flutracker website. We also searched MEDLINE and Pub Med for the keywords: Middle East respiratory syndromecoronavirus, MERS-Co V in combination with pediatric, children, childhood, infancy and pregnancy from the initial discovery of the virus in 2012 to 2016. The retrieved articles were also read to further find other articles. Relevant data were placed into an excel sheet and analyzed accordingly. Descriptive analytic statistics were used in the final analysis as deemed necessary.RESULTS From June 2012 to April 19, 2016, there were a total of 31 pediatric MERS-Co V cases. Of these cases 13(42%) were asymptomatic and the male to female ratio was 1.7:1. The mean age of patients was 9.8 ± 5.4 years. Twenty-five(80.6%) of the cases were reported from the Kingdom of Saudi Arabia. The most common source of infection was household contact(10 of 15 with reported source) and 5 patients acquired infection within a health care facility. Using real time reverse transcriptase polymerase chain reaction of pediatric patients revealed that 9 out of 552(1.6%) was positive in the Kingdom of Saudi Arabia. CONCLUSION Utilizing serology for MERS-CoV infection in Jordan andSaudi Arabia did not reveal any positive patients. Thus, the number of the pediatric MERS-CoV is low; the exact reason for the low prevalence of the disease in children is not known. | Jaffar A Al-Tawfiq Rana F Kattan Ziad A Memish | 2016 | World Journal of Clinical Pediatrics2016，5，4： | 8 |
| 2 | Middle East respiratory syndrome coronavirus in pediatrics: a report of seven cases from Saudi Arabia显示文摘Infection with Middle East respiratory syndrome coronavirus (MERS-CoV) emerged in 2012 as an important respiratory disease with high fatality rates of 40%—60%. Despite the increased number of cases over subsequent years, the number of pediatric cases remained low. A review of studies conducted from June 2012 to April 19, 2016 reported 31 pediatric MERS-CoV cases. In this paper, we present the clinical and laboratory features of seven patients with pediatric MERS. Five patients had no underlying medical illnesses, and three patients were asymptomatic. Of the seven cases, four (57%) patients sought medical advice within 1-7 days from the onset of symptoms. The three other patients (43%) were asymptomatic and were in contact with patients with confirmed diagnosis of MERS-CoV. The most common presenting symptoms were fever (57%), cough (14%), shortness of breath (14%), vomiting (28%), and diarrhea (28%). Two (28.6%) patients had platelet counts of < 150 ×10^9/L, and one patient had an underlying end-stage renal disease. The remaining patients presented with normal blood count, liver function, and urea and creatinine levels. The documented MERS-CoV Ct values were 32 38 for four of the seven cases. Two patients (28.6%) had abnormal chest radiographic findings of bilateral infiltration. One patient (14.3%) required ventilator support, and two patients (28.6%) required oxygen supplementation. All the seven patients were discharged without complications. | Sarah H. Alfaraj Jaffar A. Al-Tawfiq Talal A. Altuwaijri Ziad A. Memish | 2019 | Frontiers of Medicine2019，13，1： | 3 |
| 3 | Tuberculous spondylitis:analysis of 69 cases from saudi arabia显示文摘 | Alothman A Memish Z A Awada A | 2001 | Spine2001，26，24： | 1 |
| 4 | Prevalence of MERS- CoV nasal carriage and compliance with the Saudi health recommendations among pilgrims attending the 2013 Hajj 显示文摘 | Memish ZA Assiri A Almasri M | 2014 | J Infect Dis2014，210，7： | 1 |
| 5 | Knnwlcdgc, practi~:e,atld at- tiLude among Iranian nurses,midwives,and sLudcnts regarding standard isolation preeautions显示文摘 | Askarian M Memish ZA Khan AA | 2007 | lnfect Conlrol Hosp Epidemi- nl2007，28，2： | 1 |
| 6 | A randomized clinical trial to compare the efects of a heat and moisture exchanger with a heated humidifying system on the occurrence rate of ventilator-associated pneumonia显示文摘 | Memish Z A Oni G A Djazmati W | 2001 | Am J Infect Control2001，29，5： | 1 |
| 7 | Rate,risk factors and outcomes of catheter-related bloodstream infection in a paediatric intensive care unit in Saudi Arabla显示文摘 | ALMUNEEF M A MEMISH Z A BALKHY H H | 2006 | J Hosp Infect2006，62，2： | 1 |
| 8 | Community case clusters of Middle East Respiratory Syndrome coronavirus in Hafr Al-Batin, Kingdom of Saudi Arabia: a descriptive genomic study 显示文摘 | Memish ZA Cotten M Watson S J | 2014 | Int J Infect Dis2014，23，： | 1 |
| 9 | Middle East respiratory syndrome coronavirus disease in children显示文摘 | Ziad A Memish Jaffar A A1-Tawfiq Abdullah Assiri | 2014 | Pedi- atr Infect Dis J2014，，33： | 1 |
| 10 | Hajj:infectious disease surveillance and control显示文摘 | Memish ZA Zumla A Alhakeem RF | 2014 | Lancet2014，383，9934： | 1 |
| 11 | Prevalence of needle stick injuries among dental, nursing and midwifery students in Shiraz, Iran显示文摘 | Mehrdad Askarian Leila Malekmakan Ziad A Memish | 2012 | GMS Kraukenhhyg Inter- diszip2012，7，1： | 1 |
| 12 | Mass gathering medicine:2014 Hajj and Umra preparation as a leading example显示文摘 | Al-Tawfiq JA Memish ZA | 2014 | Int J Infect Dis2014，27，： | 1 |
| 13 | Antimicrobial therapeuticdeterminants of outcomes fromseptic shock among patients with cirrhosis显示文摘 | ARABI YM DARA SI MEMISH Z | 2012 | Hepatology2012，56，6： | 1 |
| 14 | A randomized clinical trial to compare the effects of a heat and moisture exchanger with a heated humidifying system on the occurrence rate of ventilator-associated pneumonia显示文摘 | Ziad A. Memish Gbolahan A. Oni Wajih Djazmati Gwen Cunningham Manuel W. Mah | 2001 | AJIC: American Journal of Infection Control2001，，5： | 1 |
| 15 | Prevalence of needle stick injuries among dental,nursing and midwifery students in Shiraz,Iran显示文摘 | Mehrdad Askarian Leila Malekmakan Ziad A Memish | 2012 | GMS Krankenhhyg Interdiszip2012，7，1： | 1 |
| 16 | Prevalence of needle stick injuries among dental, nursing and midwifery students in Shiraz, Iran显示文摘 | Askarian M Malekmakan L Memish Z A | 2012 | GMS Krankenhhyg Interdiszip2012，7，1： | 1 |
| 17 | Invasive meningococcal disease and travel显示文摘 | Memish ZA Goubeaud A Br(o)ker M | | 0，，04： | 1 |
| 18 | Ventilator - associated pneumonia in adults in developing countries: a systematic review 显示文摘 | Arabi Y AI - Shirawi N Memish Z | 2008 | Int J Infect Dis2008，12，5： | 1 |
| 19 | Family cluster of Middle East respiratory syndrome coronavirus infections 显示文摘 | Memish ZA Zumla AI AI-Hakeem RF | 2013 | N Engl J Med2013，368，26： | 1 |
| 20 | Antiretroviral therapy,CD4,viral load,and disease stage in HIV patients in Saudi Arabia:a 2001-2013cross-sectional study显示文摘 | Memish ZA Al-Tawfiq JA Filemban SM | 2015 | J Infect Dev Ctries2015，9，7： | 1 |
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