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| 1 | Vanishing bile duct syndrome in human immunodeficiency virus infected adults:A report of two cases显示文摘Vanishing bile duct syndrome(VBDS) is a group of rare disorders characterized by ductopenia,the progressive destruction and disappearance of intrahepatic bile ducts leading to cholestasis.Described in association with medications,autoimmune disorders,cancer,transplantation,and infections,the specific mechanisms of disease are not known.To date,only 4 cases of VBDS have been reported in human immunodeficiency virus(HIV) infected patients.We report 2 additional cases of HIV-associated VBDS and review the features common to the HIV-associated cases.Presentation includes hyperbilirubinemia,normal liver imaging,and negative viral and autoimmune hepatitis studies.In HIV-infected subjects,VBDS occurred at a range of CD4+ T-cell counts,in some cases following initiation or change in antiretroviral therapy.Lymphoma was associated with two cases;nevirapine,antibiotics,and viral co-infection were suggested as etiologies in the other cases.In HIV-positive patients with progressive cholestasis,early identification of VBDS and referral for transplantation may improve outcomes. | Ana Paula Oppenheimer Christopher Koh Mary McLaughlin John C Williamson Thomas D Norton Jennifer Laudadio Theo Heller David E Kleiner Kevin P High Caryn G Morse | 2013 | World Journal of Gastroenterology2013，19，1： | 8 |
| 2 | The role of the molecular chaperone heat shock protein A2 (HSPA2) in regulating human sperm-egg recognition显示文摘在人的不孕病人的精子在场的最普通的损害之一是精子鸡蛋识别的自发的失败。尽管这个唯一的细胞的相互作用现在能被象 intracytoplasmic 精子注射(ICSI ) 那样的帮助繁殖策略乐意地绕过,最近的大规模流行病学的研究鼓励了这种技术的小心的使用并且为对为有缺点的精子鸡蛋识别负责的机制的进一步的研究加亮需要。这个领域里的以前的工作证实了为卵母细胞相互作用负责的精子领域在动态地在女繁殖的道在 epididymal 成熟和 capacitation 期间被修改以前在精子发生期间被形成。当为这些顺序的 maturational 事件的规定负责的因素无疑是复杂的时,新兴的研究识别了分子的女伴,加热吃惊蛋白质 A2 (HSPA2 ) ,,在人的精子的这些事件的一个关键管理者。HSPA2 是支持合拢,运输,和集会蛋白质建筑群的 70 kDa 热吃惊蛋白质家庭的一个充实睾丸的成员并且断然被相关与在 vitro 授精(IVF ) 成功。而且,从人的精子 proteome 减少了 HSPA2 的表示为跟随 IVF 和 ICSI 的积云矩阵疏开,精子鸡蛋识别和授精导致一个损害能力。在这评论,我们考虑在精子功能支持 HSPA2 的角色的证据并且探索它被在不肥沃的病人的精子弄空的潜在的机制。进管理精子的分子的机制的如此的信息提议小说卓见工作。 | Brett Nixon Elizabeth G Bromfield Matthew D Dun Kate A Redgrove Eileen A McLaughlin R John Aitken | 2015 | Asian Journal of Andrology2015，17，4： | 8 |
| 3 | Use of polymerase chain reaction for rapid detection of gene insertions in whole yeast cells显示文摘 | Sathe G M OBrien S Mclaughlin M M | 1991 | Nucleic Acids Res1991，19，： | 2 |
| 4 | Bias correction for individual realization laser Doppler measurements in turbulent flows显示文摘 | Tiedermann W G | 1973 | Phys of Fluids1973，16，： | 1 |
| 5 | Differential proton sensitivity of related G protein-coupled receptors T cell death-associated gene 8 and G2A expressed in immune cells显示文摘 | Radu C G Nijagal A McLaughlin J | 2005 | Proc Natl Acad Sci USA2005，102，5： | 1 |
| 6 | Increased salinity causes elevated cadmium concentrations in field-grown potato tubers 显示文摘 | MCLAUGHLIN M J PALMER L T TILLER K G | 1994 | Journal of Environmental Quality1994，23，： | 1 |
| 7 | Toward a Descriptive Stakeholder Theory: An Organizational Life Cycle Approach显示文摘 | JAWAHAR I McLAUGHLIN G | 2001 | Academy of Management Review2001，，26： | 1 |
| 8 | Prevention of elevated cholesterolemia in monkeys by alfalfa saponins显示文摘 | Mallnow M Mclaughlin P Kohler G | 1977 | Ster- oids1977，29，1： | 1 |
| 9 | High diversity andwidespread occurrence of mitotic spore mats in ectomycorrhizalPezizales显示文摘 | Healy R A Smith M E Bonito G M Pfister D H Ge Z W Guevara G G ’ Williams G Stafford K Kumar L Lee T HobartC Trappe J Vilgalys R McLaughlin D J | 2013 | Molecular Ecology2013，22，： | 1 |
| 10 | Use of polymerase chain reaction for rapid detection of gene insertions in whole yeast cells显示文摘 | Sathe G M O'Brien S McLaughlin M M | 1991 | Nucl Acids Res1991，19，17： | 1 |
| 11 | Review:The behavior and environment impact of contaminants in fertilizers显示文摘 | Mclaughlin M L Tiller K G Naidu R | 1996 | Soil Res1996，34，： | 1 |
| 12 | Time-correlated force production measurements of the dielectric harrier dis- charge plasma aerodynamic actuator 显示文摘 | Enloe C L Mcharg M G McLaughlin T E | 2008 | Journal of Applied Physics2008，103，7： | 1 |
| 13 | Ethylene from ethanol over zeolite catalysts显示文摘 | MAO L V R LEVESQUE P MCLAUGHLIN G | 1987 | Applied Catalysis1987，34，： | 1 |
| 14 | Broadband MIMO-OFDM wireless communications 显示文摘 | Stnber G L Barry J R McLaughlin S W | 2004 | Proceedings of the IEEE2004，92，2： | 1 |
| 15 | School Mental Health Resources and Adolescent Mental Health Service Use 显示文摘 | Green J G McLaughlin K A Alegria M etc | 2013 | Journal of the American Academy of Child & Adolescent Psychiatry2013，，5： | 1 |
| 16 | Is there asimple way to identify insulin-resistant individuals at in creased risk of cardiovascular disease?显示文摘 | Reaven G Abbasi F | 2005 | Am J Cardiol2005，96，3： | 1 |
| 17 | Detection of Babesia bovis using DNA hybridization显示文摘 | Mclaughlin G L Edlind T D Ihler G M | 1986 | J Protozool1986，33，： | 1 |
| 18 | High value renewable energy from prairie grasses显示文摘 | McLaughlin S B Ugarte D G D L Garten C T | 2002 | Environmen- tal Science and Technology2002，36，10： | 1 |
| 19 | Validation of the COSMED K4 b2 portable metabolic system显示文摘 | McLaughlin J E King G A Howley E T | 2001 | Int J Sports Med2001，22，4： | 1 |
| 20 | Bandwidth efficient single carrier systems with frequency domain equalisation显示文摘 | Li Y McLaughlin S Cruickshank D G M | 2005 | Electronics Letters2005，41，15： | 1 |
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