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| 1 | Significance of the balance between intracellular glutathione and polyethylene glycol for successful release of small interfering RNA from gold nanoparticles显示文摘为特定的基因 silencing 的小介入 RNA (siRNAs ) 的治疗学的诺言依赖于到细胞质的功能的 siRNAs 的成功的交货。他们到一个确定的交货平台的变化形式例如金 nanoparticles,为治疗疾病并且推进我们细胞的过程的理解提供巨大的潜力。他们的成功或失败依赖于两个进房间和功能的 siRNA 的随后的细胞内部的版本的 nanoparticles 的举起。在这研究,利用金 nanoparticle 对 C-MYC 的 调停siRNA 的交货,我们试图决定我们是否能完成在一个癌症房间击倒与细胞内部的谷胱甘肽的底层排队,并且如果有的话,聚乙烯乙二醇(木钉)决定影响 ligand 密度在上击倒,考虑到决定最佳的 nanoparticle 设计完成 C-MYC 击倒。我们表明那,不管木钉密度,在有相对低的谷胱甘肽层次的房间击倒能被完成,以及为在细胞内部的环境的劈开的 siRNA 的可获得性上的木钉的位的阻碍者的可能的效果。当击倒时,金 nanoparticle 举起经由传播电子显微镜学和集体光谱学被表明被在里面房间 westerns 和 BrdU 加入分别地在蛋白质和生理的层次(在 S 阶段的房间) 决定。 | Mark McCully Yulan Hernandez Joao Conde Pedro V. Baptista Jesus M. de la Fuente Andrew Hursthouse David Stirling Catherine C. Berry | 2015 | Nano Research2015，8，10： | 2 |
| 2 | Vascular pathology of homocysteinemia, implications for the pathogenesis of arteriosclerosis 显示文摘 | MCCULLY KS | 1969 | Am J Pathol1969，56，1： | 1 |
| 3 | A Nitrogen-Fixing Endophyte of Sugarcane Stems(A New Role for the Apoplast)显示文摘 | Dong Z Canny M J McCully M E | 1994 | American Society of Plant Biologists1994，105，4： | 1 |
| 4 | Vascular pathology of homocysteinemia impli-cations for the pathogenesis of arteriose显示文摘 | McCully KS | 1969 | Am J Pathol1969，56，1： | 1 |
| 5 | Vascular pathology of homoeysteineraia: implications for the pathogensis of arteriosclerosis显示文摘 | McCully KS | 1969 | Am J Pathol1969，56，1： | 1 |
| 6 | Vascular pathology of homocysteinemia:implications for the pathgensis of arteriosclerosis显示文摘 | MCCULLY KS | 1969 | Am J Pathol1969，56，1： | 1 |
| 7 | Vascular pathology of homocysteinemia:implications for the pathogenesis of arteriosclerosis显示文摘 | McCully KS | | 0，，01： | 1 |
| 8 | Vascular pathology of homocysteinemia:implications for the pathogenesis of artheriosclerosis显示文摘 | McCully KS | 1969 | Am J Pathol1969，56，1： | 1 |
| 9 | Adengosine-enhanced ischemic pre-conditioning : adenosine receptor involvement during ischemia and reperfusion 显示文摘 | McCully JD oyoda Y Uematsu M | 2001 | Am J Physiol Heart Circ Physiol2001，280，2： | 1 |
| 10 | Vascular pathology of homocysteinemia:implications for the pathogenesis of arteriosclerosis显示文摘 | McCully KS | 1969 | Am J Pathol1969，56，1： | 1 |
| 11 | Adenosine enhanced ischemic preconditioning:adenosine receptor involvement during ischemia and reperfusion显示文摘 | McCully JD Toyoda Y Uematsu M | 2001 | Am J Physiol Heart Circ Physiol2001，280，2： | 1 |
| 12 | Vascular transport and soybean nodule function:nodule xylem is a blind alley, not a throughway显示文摘 | WALSH K B M E MCCULLY M J CUNNY | 1989 | Plant Cell Environment1989，12，： | 1 |
| 13 | Myocardial dysfunction associated with brain death:clinical,echocardiographic,and pathologic features 显示文摘 | McCully RB Wijdicks EF | 2001 | J Heart Lung Transplant2001，20，3： | 1 |
| 14 | Vascular pathology of homocystemia:Implications for the pathogenesis of arteriosclerosis显示文摘 | McCully KS | 1969 | Am J Patho1969，56，2： | 1 |
| 15 | Vascular pathology of homocysteinemia:implications for the pathogenesis of arteriosclerosis显示文摘 | McCully KS | 1969 | Am J Pathol1969，56，： | 1 |
| 16 | Vascular pathology of homocysteinemia implications for the pathogenesis of arteriosclerosis显示文摘 | McCully KS | 1969 | Am J Patho1969，56，1： | 1 |
| 17 | Homocysteine and lipid metabolism in atherogenisis :effect of of the homocysteine thiolactonyl derivates, thioretinaco and thioretinamide显示文摘 | Mccully KS Olszewski AJ Vezaridis MP | 1990 | A therosclerosis1990，83，23： | 1 |
| 18 | Myocardial dysfunction associated with brain death: clinical, echocardiographic and pathologic features显示文摘 | McCully RB Wijdicks EF | 2001 | Heart Lung Transplant2001，20，3： | 1 |
| 19 | Vascular pathology of homocysteinemia:implication for the pathogenesis of arteriosclerosis显示文摘 | McCully KS | 1969 | Am J Pathol1969，56，1： | 1 |
| 20 | Vascule Pathology of Homocysteinemia:Implications for the Pathogenesis of Arteriosclerosis显示文摘 | McCully K S | 1969 | Am J Pathol1969，56，： | 1 |
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