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| 1 | Predictors of disease severity in ulcerative colitis patients from Southwestern Ontario显示文摘AIM:To understand the demographic characteristics of patients in Southwestern Ontario,Canada with ulcerative colitis(UC)in order to predict disease severity. METHODS:Records from 1996 to 2001 were exam- ined to create a database of UC patients seen in the London Health Sciences Centre South Street Hospital Inflammatory Bowel Disease Clinic.To be included, patients'charts were required to have information of their disease presentation and a minimum of 5 years of follow-up.Charts were reviewed using standardized data collection forms.Disease severity was generated during the chart review process,and non-endoscopic Mayo Score criteria were collected into a composite. RESULTS:One hundred and two consecutive patients'data were entered into the database.Demographic analyses revealed that 51%of the patients were male, the mean age at diagnosis was 39 years,13.7%had a first degree relative with inflammatory bowel disease (IBD),61.8%were nonsmokers and 24.5%were ex-smokers.In 22.5%of patients the disease was limited to the rectum,in 21.6%disease was limited to the sigmoid colon,in 22.5%disease was limited to the left colon,and 32.4%of patients had pancolitis. Standard multiple regression analysis which regressed a composite of physician global assessment of disease severity,average number of bowel movements,and average amount of blood in bowel movements on year of diagnosis and age at time of diagnosis was significant,R 2=0.306,F(7,74)=4.66,P<0.01. Delay from symptoms to diagnosis of UC,gender, family history of IBD,smoking status and disease severity at the time of diagnosis didnot significantly predict the composite measure. CONCLUSION:UC severity is associated with younger age at diagnosis and year of diagnosis in a longitudinal cohort of UC patients,and may identify prognostic UC indicators. | Lee S Roth Nilesh Chande Terry Ponich Maya L Roth James Gregor | 2010 | World Journal of Gastroenterology2010，16，2： | 4 |
| 2 | Intestinal epithelial vitamin D receptor signaling inhibits experimental colitis显示文摘 | Liu Weicheng Chen Yunzi Golan Maya Aharoni Annunziata Maria L Du Jie Dougherty Urszula Kong Juan Musch Mark Huang Yong Pekow Joel Zheng Changqing Bissonnette Marc Hanauer Stephen B Li Yan Chun | 2013 | Journal of Clinical Investigation2013，，9： | 2 |
| 3 | Diagnostic approaches for diabetic cardiomyopathy and myocardial fibrosis显示文摘 | Maya L Villarreal FJ | 2010 | J Mol Cell Cardiol2010，48，3： | 1 |
| 4 | Derivatization of performed polymers to produce ceramic precursor s显示文摘 | | 1990 | J Am Ceram Soc1990，73，9： | 1 |
| 5 | Complete Degradation of Perchlorate in Ferric Chloride and Hydrochloric Acid under Controlled Temperature and Pressure显示文摘 | Gu B Brown G M Maya L | 2003 | Environmental Science & Technology2003，37，10： | 1 |
| 6 | Generation of oscillation by the p53-Mdm2 feedback loop: a theoretical and experimental study 显示文摘 | LEV B R MAYA R SEGEL L A | 2000 | Proceedings of the National Academy of Sciences USA2000，97，11： | 1 |
| 7 | Diagnostic approaches for diabetic cardiomyopathy and myocardial fibrosis显示文摘 | Maya L Villarreal FJ | 2010 | J molecul cellular cardiol2010，48，3： | 1 |
| 8 | Reactive sputtering of titanium diboride or titanium disilicide显示文摘 | Maya L Vallet C E Fiedor J N | 1997 | J Vac Sci Technol A1997，15，4： | 1 |
| 9 | Oligodimethyl- siloxane Linked Cyanate Ester Resins显示文摘 | Maya E M Snow A W Buckley L J | 2002 | Macromolecules2002，35，2： | 1 |
| 10 | In- fluence of wastewater characteristics on methane potential in food-processing industry wastewaters显示文摘 | MAYA ALTAMIRA L BAUN A ANGELIDAKI I | 2008 | Water Research2008，42，89： | 1 |
| 11 | Diagnostic approaches for diabetic cardiomyopath and myocardial fibrosis显示文摘 | Maya L Villarreal FJ | 2010 | J Mol Cell Car- diol2010，48，3： | 1 |
| 12 | Covalent attachment of gold nanoparticles to DNA templates 显示文摘 | Stevenson K A Muralidharan G Maya L | 2002 | J Nanosci and Nanotech2002，2，34： | 1 |
| 13 | Plasma-assisted reduction of carbon dioxide in the gas phase显示文摘 | Maya L | 2000 | Vac Sci Tech A2000，18，1： | 1 |
| 14 | Diagnostic approaches for diabetic eardiomyopathy and myocardial fibrosis显示文摘 | Maya L Villarreal F J | 2010 | J Mol Cell Cardiol2010，48，3： | 1 |
| 15 | Copper Nitride Thin Films Prepared by dc Sputte- ring 显示文摘 | MAYA L | 1993 | Materials Research Society Symposium Proceed- ings1993，282，： | 1 |
| 16 | Synthesis of fluorinated oligomers toward physical vapor deposition molecular electronics candidates显示文摘 | Maya F Chanteau S H Cheng L | 2005 | Chemistry of Materials2005，17，6： | 1 |
| 17 | Covalent Nitrides for Maskless Laser Writing of Mi- croscopic Metal Lines 显示文摘 | MAYA L | 1993 | Materials Research Society Sym- posium Proceedings1993，282，： | 1 |
| 18 | Genetic study of the melanin-concentrating hormone receptor 2 ( MCHR2 ) in childhood and adulthood severe obesity 显示文摘 | Maya G Vincent V Cecile L | 2007 | J Clin Endocrin Metab2007，92，11： | 1 |
| 19 | 显示文摘 | Contreras M C Maya C A Q Pez M L | 2005 | Jourllal of Crystal Growth2005，278，： | 1 |
| 20 | Solute and isotopic geochemistry and groundwater flow in the Central Wasatch Range, Utah 显示文摘 | Maya A L Loucks M D | 1995 | Journal of Hydrology1995，172，： | 1 |
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