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| 1 | Risk assessment for severe clinical attachment loss in an adult population 显示文摘 | Bouchard P Boutouyrie P Mattout C | 2006 | Periodontol2006，77，3： | 1 |
| 2 | Risk assessment for severe clinical attachment loss in an adult population 显示文摘 | Bouchard P Boutouyfie P Mattout C | 2006 | Periodontol2006，77，3： | 1 |
| 3 | Laminopathic mutations interfere with the assembly ,localization, and dynamics of nuclear lamins 显示文摘 | Wiesel N Mattout A Meleer S | 2008 | Proc Natl Acad Sci USA2008，105，1： | 1 |
| 4 | Laminopathie mutations interfere with the assembly, localization, and dynamics of nuclear lamins 显示文摘 | Wiesel N Mattout A Melter S | 2008 | Proc Natl Acad Sci USA2008，105，1： | 1 |
| 5 | EEG and MEG data analysis in SPM8显示文摘 | Litvak V Mattout J Kiebel S | 2011 | Comput Intell Neurosci2011，2011，85： | 1 |
| 6 | Global epigenetic changes during somatic cell reprogramming to iPS cells显示文摘 | Mattout A Biran A Meshorer E | | 0，，06： | 1 |
| 7 | Risk assessment for severe clinical attachment loss in an adult population 显示文摘 | Bouchard P Boutouyrie P Mattout C | 2006 | J Periodontol2006，77，3： | 1 |
| 8 | Risk assessment for severe clinical attachment loss in an adult population显示文摘 | Bouchard P Boutouyrie P Mattout C | 2006 | J Pe- riodontol2006，77，3： | 1 |
| 9 | Global epigenetic changes during somatic cell reprogramming to iPS cells显示文摘Embryonic stem cells(ESCs)exhibit unique chromatin features,including a permissive transcriptional program and an open,decondensed chromatin state.Induced pluripotent stem cells(iPSCs),which are very similar to ESCs,hold great promise for therapy and basic research.However,the mechanisms by which reprogramming occurs and the chromatin organization that underlies the reprogramming process are largely unknown.Here we characterize and compare the epigenetic landscapes of partially and fully reprogrammed iPSCs to mouse embryonic fibroblasts(MEFs)and ESCs,which serves as a standard for pluripotency.Using immuno-fluorescence and biochemical fractionations,we analyzed the levels and distribution of a battery of histone modifications(H3ac,H4ac,H4K5ac,H3K9ac,H3K27ac,H3K4me3,H3K36me2,H3K9me3,H3K27me3,and gH2AX),as well as HP1a and lamin A.We find that fully reprogrammed iPSCs are epigenetically identical to ESCs,and that partially reprogrammed iPSCs are closer to MEFs.Intriguingly,combining both time-course reprogramming experiments and data from the partially reprogrammed iPSCs,we find that heterochromatin reorganization precedes Nanog expression and active histone marking.Together,these data delineate the global epigenetic state of iPSCs in conjunction with their pluripotent state,and demonstrate that heterochromatin precedes euchromatin in reorganization during reprogramming. | Anna Mattout Alva Biran Eran Meshorer | 2011 | Journal of Molecular Cell Biology2011，3，6： | 1 |
| 10 | Botulinum toxin augmented bilateral lateral rectus recession versus three muscles surgery in large-angle intermittent exotropia显示文摘AIM: To report the surgical outcomes of correcting large angle intermittent exotropia in adult patients by bilateral lateral rectus muscle recession with intraoperative use of botulinum toxin and to compare the results with those of bilateral lateral rectus muscle recession and unilateral medial rectus resection. METHODS: The medical records of patients who underwent surgical correction of large angle intermittent exotropia [exotropia >50 prism dioptre(PD)] were retrospectively reviewed. Two groups of patients were identified;Group Ⅰ(21 patients) had bilateral lateral recti recession augmented with intraoperative botulinum toxin A(BTA) injection into the recessed muscles and group Ⅱ(30 patients) were treated by bilateral lateral recti recession with unilateral medial rectus muscle resection. Preoperative data were extracted for age, gender, refraction, type of exotropia, angle of stereopsis and angle of deviation. The main outcome measures were the postoperative angle of deviation and stereoacuity angle by Titmus test measured at the end of one year of postoperative follow up. RESULTS: By the end of the first postoperative year, 10 patients in group Ⅰ(47.6%) and 20 patients in group Ⅱ(66.7%) achieved esotropia/esophoria <5 PD or exotropia/exophoria <10 PD. The difference in surgical success rate was not statistically significant(P=0.1) but there was a statistically significant higher rate of undercorrection in group Ⅰ(P=0.03). On the other hand, 3 patients in group Ⅰ(14.3%) and 5 patients in group Ⅱ(16.7%) had improved stereopsis;this difference in the sensory outcome was not statistically significant(P=0.8). In the BTA augmented surgery group, good stereoacuity and smaller preoperative angle of deviation were associated with significantly higher surgical success rate(P=0.004, 0.01 respectively). CONCLUSION: BTA augmented bilateral lateral recti recession is associated with higher rate of undercorrection as compared to bilateral lateral recti recession with unilateral medial rectus resection in the correction of large angle intermittent exotropia. The surgical success rate in BTA augmented surgery group is observed to be higher in patients with preoperative smaller angle of deviation and in patients with good stereoacuity. | Hala Kamal Mattout Sameh Mosaad Fouda Wael M El-Haig | 2022 | International Journal of Ophthalmology(English edition)2022，15，10： | 0 |
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