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| 1 | Type 1 diabetes and polyglandular autoimmune syndrome: A review显示文摘Type 1 diabetes(T1D) is an autoimmune disorder caused by inflammatory destruction of the pancreatic tissue. The etiopathogenesis and characteristics of the pathologic process of pancreatic destruction are well described. In addition, the putative susceptibility genes for T1 D as a monoglandular disease and the relation to polyglandular autoimmune syndrome(PAS) have also been wellexplored. The incidence of T1 D has steadily increased in most parts of the world, especially in industrialized nations. T1 D is frequently associated with autoimmune endocrine and non-endocrine diseases and patients with T1 D are at a higher risk for developing several glandular autoimmune diseases. Familial clustering is observed, which suggests that there is a genetic predisposition. Various hypotheses pertaining to viral- and bacterialinduced pancreatic autoimmunity have been proposed, however a definitive delineation of the autoimmune pathomechanism is still lacking. In patients with PAS, pancreatic and endocrine autoantigens either colocalize on one antigen-presenting cell or are expressed on two/various target cells sharing a common amino acid, which facilitates binding to and activation of T cells. The most prevalent PAS phenotype is the adult type 3 variant or PAS type Ⅲ, which encompasses T1 D and autoimmune thyroid disease. This review discusses the findings of recent studies showing noticeable differences in the genetic background and clinical phenotype of T1 D either as an isolated autoimmune endocrinopathy or within the scope of polyglandular autoimmune syndrome. | Martin P Hansen Nina Matheis George J Kahaly | 2015 | World Journal of Diabetes2015，6，1： | 7 |
| 2 | Assessment of the vortex method for large eddy simulation inlet conditions显示文摘 | Mathey F Cokljat D Bertoglio J P | 2006 | Progressin Computational Fluid Dynamics2006，6，13： | 1 |
| 3 | Reduction of ethylene-induced physiological disorders of carrots and iceberg lettuce by 1 -methycyclopropene 显示文摘 | Fan X Matheis J P | 2000 | Hortscience2000，35，7： | 1 |
| 4 | Yellowing of broccoli in storage is reduced by 1-methycyclopropene 显示文摘 | Fan X T James P Matheis J P | 2000 | Hortscience2000，35，5： | 1 |
| 5 | Safety and immunogenicity of hepatitis B vaccine formulated with a novel adjuvant system显示文摘 | Thoelen S Van Damme P Mathei C el al | 1998 | Vaccine1998，16，7： | 1 |
| 6 | Role of L-arginine-nitric oxide pathway in myocardial reoxygenation injury显示文摘 | Matheis G Sherman M P Buckberg G D | 1992 | Am J Physiol1992，262，10： | 1 |
| 7 | Motivation for psy-chotherapy in patients with functional gastrointestinal dis-orders显示文摘 | Martens U Enck P Matheis A | 2010 | Psychosomatics2010，51，3： | 1 |
| 8 | Review of the pathophysiology and manage- ment of postoperative ileus 显示文摘 | Mathei P Rombeau JL | 2006 | World J Surg2006，30，8： | 1 |
| 9 | 显示文摘 | LA_MPIN J P MATHEY F | 1974 | J Organomet Chem1974，71，： | 1 |
| 10 | Pulmonary resection and ECMO: A salvage therapy for penetrating lung trauma 显示文摘 | Ineaqnoli P Blaise H Mathey C | 2012 | Ann Fr Anesth Reanim2012，31，78： | 1 |
| 11 | Motivation for psychotherapy in patients with functional gastrointestinal disorders显示文摘 | Martens U Enck P Matheis A | 2010 | Psychosomatics2010，51，3： | 1 |
| 12 | Arole for jasmonates in climacteric fruit ripening显示文摘 | Fan X T Matheis J P Fellman J K | 1998 | Planta1998，204，： | 1 |
| 13 | Treatment of gefitinib-assoeiated folliculitis 显示文摘 | Matheis P Socinski M A Burkhart C | 2006 | J Am Acad Dermatol2006，55，4： | 1 |
| 14 | Left ventricular relaxation and filling pttern in different forms of left ventricular hypertrophy:an echocardiographic study显示文摘 | Hanrath P Mathey DG Siegert R | 1980 | Am J Cardiol1980，45，： | 1 |
| 15 | A role for jasmonates in climacteric fruit ripening显示文摘 | Fan X T Matheis J P Fellman J K | 1998 | Planta1998，，204： | 1 |
| 16 | Role of Larginine-nitric oxide pathway in myocardial reoxygenation injury显示文摘 | Matheis G Shermn M P Buckberg G D | 1992 | Am J Physiol1992，262，： | 1 |
| 17 | Vibrational study of the anion, of some MPS3 layered compounds (M=Fe, Co, Ni,In2/3), and of their intercalates with cations显示文摘 | Sourisseau C Forgerit J P Mathey Y | 1983 | J Solid State Chem1983，49，： | 1 |
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