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| 1 | Interstitial cells of Cajal in the gut-A gastroenterologist’s point of view显示文摘Alterations of normal function of interstitial cells of Cajal (ICC) are reported in many intestinal disorders. Diagnosis of their involvement is rare (infrequent), but necessary to propose a specifi c treatment. This article reviews the place of ICC in the pathogenesis of achalasia, gastroesophageal reflux disease, infantile hypertrophic pyloric stenosis, chronic intestinal pseudoobstruction and slow transit constipation. Moreover we discuss the role of the Cajal cells in the development of stromal tumors of the gastrointestinal tract. | Lucian M Negreanu Philippe Assor Bogdan Mateescu Catalin Cirstoiu | 2008 | World Journal of Gastroenterology2008，14，41： | 27 |
| 2 | Self-stabilized chitosan and its complexes with carboxymethyl starch as excipients in drug delivery显示文摘This study focuses on the behavior of chitosan(CHI)and its polyelectrolyte complexes with carboxymethyl starch(CMS)used as monolithic matrices with acetaminophen as drug tracer.Two different chitosan grades were tested alone or associated in various ratios with CMS as excipients for tablets obtained by direct compression.The degree of deacetylation(DDA)of CHI,estimated from 1H NMR and FTIR data,was correlated with X-ray diffraction and scanning electron microscopy(SEM)to evaluate structural organization of the monolithic matrices.In vitro drug dissolution assays showed major differences in CHI kinetic profiles between tablets exposed to acidic medium for 2h(to mimick gastric passage)prior to dissolution in simulated intestinal fluid(SIF),and those administered directly to SIF.Prior exposure to acidic SGF conducted to longer dissolution profiles(release completed after 16 h)and preservation of tablet shape,whereas tablets directly incubated in SIF were rapidly disintegrated.The improved properties of chitosan matrices exposed to SGF may be related to an outer compact coating layer(visible in SEM).The effect of self-stabilization of chitosan in acidic medium was compared to that due to formation of polyelectrolyte complexes(PEC)in co-processed polymeric systems(CHI:CMS).The self-formed membrane following exposure to gastric acidity appears to help maintaining tablet integrity and allows higher drug loading,recommending CHI and its complexes with CMS as excipients for drug delivery. | Mihaela Leonida Pompilia Ispas-Szabo Mircea Alexandru Mateescu | 2018 | Bioactive Materials2018，3，3： | 4 |
| 3 | Role of capsule endoscopy Pillcam COLON 2 in patients with known or suspected Crohn’s disease who refused colonoscopy or underwent incomplete colonoscopic exam: a case series显示文摘 | L. Negreanu G. Smarandache R. B. Mateescu | 2014 | Techniques in Coloproctology2014，，3： | 2 |
| 4 | Spectral solution for unsteady annular flows between eccentric cylinders induced by transverse oscillations 显示文摘 | Mateescu D Paidoussis M P Sim W G | 1994 | Journal of Sound and Vibration1994，177，5： | 1 |
| 5 | Using NDIS intermediate drivers for extending the protocol stack:A case study显示文摘 | Floroiu J W Ionescu T C Ruppeltr R Henckel B Mateescu M | 2001 | Computer Communications2001，，24： | 1 |
| 6 | Primary malignant fibrous histiocytoma of the right ventricle: case report and review of the literature显示文摘 | Balaceanu A Mateescu D Diaconu C | 2010 | J Ultrasound Med2010，29，4： | 1 |
| 7 | Gene expression in sexually dimorphic muscles in sheep显示文摘 | MATEESCU R G THONNEY M L | 2002 | J Anim Sci2002，80，7： | 1 |
| 8 | Rank modulation for flash memories 显示文摘 | JIANG A MATEESCU R SCHWARTZ M | 2009 | IEEE Transactions on Information Theory2009，55，6： | 1 |
| 9 | Milk protein coatings prevent oxidative browning of apples and potatoes显示文摘 | Tien C L Vachon C Mateescu M A | 2001 | J Food Sci2001，66，： | 1 |
| 10 | Importance of dy- namic culture for evaluating osteohlast activity on dense silicon- substituted hydroxyapatite显示文摘 | Silva H M da Mateescu M Damia C | 2010 | Colloids Surf B: Biointerfaces2010，80，2： | 1 |
| 11 | Effect of testosterone on insulin-like growth factor-Ⅰ, androgen receptor, and myostatin gene expression in splenius and semitendinosus muscles in sheep显示文摘 | Mateescu RG Thonney ML | 2005 | J Anita Sci2005，83，4： | 1 |
| 12 | Overcharging of a spherical macroion by an oppositely charged polyelectro- lyte 显示文摘 | Mateescu E M Jeppesen C Pincus P | 1999 | Europhysics Letters1999，46，4： | 1 |
| 13 | Carboxymethyl high amylose starch as excipient for controlled drug release: Mechanistic study and the influence of degree of substitution显示文摘 | Marc Lemieux Patrick Gosselin Mircea Alexandru Mateescu | 2009 | International Journal of Pharmaceutics2009，，1： | 1 |
| 14 | Effect of testosterone on insu- lin-like growth factor-I, androgen receptor, and myostatin gene expression in splenius and semitendinosus muscles in sheep显示文摘 | Mateescu R G Thonney M L | 2005 | Journal of Animal Science2005，83，4： | 1 |
| 15 | Primary malignant fibrous histiocytoma of the right ventricle:case report and review of the literature显示文摘 | Balaceanu A Mateescu D Diaconu C | 2010 | J Ultasound Med2010，29，4： | 1 |
| 16 | First Pillcam Colon 2 capsule images of Whipple's disease:Case report and review of the literature显示文摘Whipple's disease is a rare chronic systemic infection determined by the Gram-positive bacillus Tropheryma whipplei.The infection usually mainly involves the small bowel,but sometimes other organs are affected as well.Since the current standard clinical and biological tests are nonspecific,diagnosis is very difficult and relies on histopathology.Here we present the case of a 52-yearold man with chronic diarrhea and weight loss whose symptoms had been evolving for 2 years and whose diagnosis came unexpectedly after capsule examination.Diagnosis was confirmed by the histopathologic examination of endoscopic biopsy samples,and treatment with co-trimoxazole resulted in remission of symptoms.We present the first images of Whipple's disease obtained with the Pillcam Colon 2 video capsule system. | Bogdan Radu Mateescu Andreea Bengus Madalina Marinescu Florica Staniceanu Gianina Micu Lucian Negreanu | 2012 | World Journal of Gastrointestinal Endoscopy2012，4，12： | 1 |
| 17 | New polymeric structures designed for the removal of Cu (Ⅱ) ions from aqueous solutions 显示文摘 | Mihaela Mocioi Ana Maria Albu Carmencita Mateescu | 2007 | Journal of Applied Polymer Science2007，103，3： | 1 |
| 18 | miR-141 and miR-200a act on ovarian tumorigenesis by controlling oxidative stress response 显示文摘 | Mateescu B Batista L Cardon M | 2011 | Nat Med2011，17，12： | 1 |
| 19 | Impact of metabolic syndrome traits on cardiovascular function: should the Adult Treatment Panel Ⅲdefinition be further stratified? 显示文摘 | Antonini-Canterin F Mateescu AD Vriz O | 2014 | J Cardiovasc Med ( Hagerstown)2014，15，10： | 1 |
| 20 | Synthesis of super fine aragonite-type calcium carbonate by precipitation in ultrasonic field显示文摘 | Mateescu C D Mocioi M Sarbu C | 2007 | European Congress of Chemical Engineering2007，，6： | 1 |
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