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| 1 | Role of β-microseminoprotein from prostate cancer initiationto recurrence: A mini-review显示文摘Medline/Pubmed articles relevant to this topic were considered using the search terms ?-microseminoprotein, MSMB, prostate secretory protein of 94 amino acids and PSP94. Full articles were retrieved when the abstract was considered relevant. In addition, other data related to this topic including our own are discussed. Summary of fi ndings-?-microseminoprotein(MSMB) is increasingly being considered as a marker for prostatecancer, as reduced levels have been associated with the disease. Here we review various aspects of this protein including its biological and physiological variants, binding proteins and immune modulation; its importance as a marker for biochemical recurrence of prostate cancer; prostate cancer related splice variants and its therapeutic utility. Two of the most important properties of MSMB are related to anticancer functions and immune modulation. Predominant expression of two(short and full-length) splice variants of MSMB has been observed from normal prostate and several other tissues. In benign prostate hyperplasia the short isoform is dominant, constituting 98% of this isoform, whereas in prostate cancer 96% constitute the fulllength isoform. The MSMB promoter single nucleotide polymorphism rs10993994 with the C allele functions as an activated cyclic adenosine monophosphate response element binding protein binding site. This C variant of rs10993994 could be responsible for the production of splice variants under variable conditions. MSMB has binding motifs to a few known proteins including immunoglobulin G and several Cysteine-rich secretory proteins family proteins. MSMB bound to these proteins is considered as immune modulating. Use of MSMB as a urinary marker for detecting aggressive prostate cancers that could resist radiation and surgical treatments, seems possible, but needs further investigation. The ratio of MSMB splice variants could also be a possible approach in understanding prostate cancers, with higher ratios indicating severe disease. | Nishi Karunasinghe Karen Bishop Pamela Murray Yuanye Xu Megan Goudie Lance Ng Shuotun Zhu Dug Yeo Han Lynnette R Ferguson Jonathan Masters Benji Benjamin Michael Holmes | 2014 | World Journal of Clinical Urology2014,3,1: | 2 |
| 2 | Subsurface issues for COz flooding of UKCS reservoirs显示文摘 | Goodyear S G Hawkyard I R Masters J H K | 2003 | Chemical engineering research and design2003,81,3: | 1 |
| 3 | Iron control in zinc pressure leach process显示文摘 | K R Buban M J Collins I M Masters | 1999 | JOM1999,51,12: | 1 |
| 4 | The role of CIM0 in the regulation of humoral and cell-mediated immunity显示文摘 | Durie F H Foy T M Masters S R | 1994 | Immunol Today1994,15,9: | 1 |
| 5 | Stable implicit motor processes despite aerobic locomotor fatigue显示文摘 | MASTERS R S W POOLTON J M MAXWELL J P | 2008 | Consciousness and cogni- tion2008,17,: | 1 |
| 6 | 14-3-3 proteins:structure,function,and regulation显示文摘 | Fu H Subramanian R R and Masters S C | 2000 | Annu Rev Pharmacol Toxicol2000,40,: | 1 |
| 7 | Why you should consider object-oriented programming techniques for finite element methods 显示文摘 | Cross J T Masters I Lewis R W | 1999 | International Journal of Numerical Methods for Heat & Fluid Flow1999,9,3: | 1 |
| 8 | Mechanical properties of triaxially braided composites: experimental and analytical results 显示文摘 | Masters J E Foye R L Pastore C M | 1993 | J Compo Technol Res1993,15,2: | 1 |
| 9 | Postclural puncture headache after ontinuous spinal anestheasia 显示文摘 | Denny Master R Preason D | 1987 | Anesth Analg1987,66,: | 1 |
| 10 | A novel receptor for Apo2L/TRAIL contains a truncated death domain显示文摘 | Masters S A Sheridan J P Pitti R M | | 0,,: | 1 |
| 11 | The Implicit Benefit of Learning Without Errors显示文摘 | Maxwell J P Masters R S W Kerr E Weedon E | 2001 | Quarterly Journal of Experimental Psychology2001,54,4: | 1 |
| 12 | A mix of plants lifts feed value from saline land显示文摘 | Masters D Norman H Dynes R | 2002 | Farming Ahead2002,130,: | 1 |
| 13 | Effect of fiber architecture parameters on deformation field and elastic moduli of 2-Dbraided composite 显示文摘 | Naik R A Ifju P G Masters J E | 1994 | Journal of Composite Materials1994,28,7: | 1 |
| 14 | Genome, transcriptome, and secretome analysis of wood decay fungus Postia placenta supports unique mechanisms of lignocellulose conversion 显示文摘 | Martinez D Challacombe J Morgenstern 1 Hibbett D Schmoll M Kubicek CP Ferreira P Ruiz-Duenas FJ Martinez AT Kersten P Hammel KE Wymelenberg AV Gaskell J Lindquist E Sabat G BonDurant SS Larrondo LF Canessa P Vicuna R Yadav J Doddapaneni H Subramanian V Pisabarro AG Lavin JL Oguiza JA Master E Henrissat B Coutinho PM Harris P Magnuson JK Baker SE Bruno K Kenealy W Hoegger PJ Kties U Ramaiya P kucas S Salamov A Shapiro H Tu H Chee CL Misra M Xie G Teter S Yaver D James T Mokrejs M Pospisek M Grigoriev IV Brettin T Rokhsar D Berka R Cullen D | 2009 | PNAS2009,106,6: | 1 |
| 15 | Passing Thoughts on the Evolutionary Stability of Implicit Motor Behaviour:Performance Retention Under Physiological Fatigue显示文摘 | Poolton J M Masters R S W Maxwell J P | 2007 | Consciousness and Cognition2007,16,2: | 1 |
| 16 | Development andvalidation of a core endurance intervention program: implicationsfor performance in college-age rowers显示文摘 | Tse M McManus A Masters R | 2005 | JStrength Cond Res2005,19,3: | 1 |
| 17 | Seed bank dynamics: The role of fungal pathogens and climate change显示文摘 | Leishman M R Masters G J Clarke I P | 2000 | Functional Ecology2000,14,: | 1 |
| 18 | Effects of vacuuming on dye penetration patterns in root canals and glass tubes显示文摘 | Higa R Torabinejad M | 1995 | J Endod1995,21,6: | 1 |
| 19 | A phase II study of 9-aminocamptothecin in advanced non-small-cell lung cancer 显示文摘 | VOKES E E ANSARI R H MASTERS G A | 1998 | Ann Oncol1998,9,10: | 1 |
| 20 | Analysis of re- sistance, cross - resistance and antimierobial combinations for Pseudomonas aeruginosa isolates from 1997 to 2009显示文摘 | Master R N Clark R B Karlowsky J A | 2011 | Int J Antimicrob Agents2011,38,4: | 1 |