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| 1 | MicroRNAs as possible biomarkers for diagnosis and prognosis of hepatitis b- and c-related-hepatocellularcarcinoma显示文摘Aim of the present review is to summarize the current knowledge about the potential relationship between mi RNAs and hepatitis B virus(HBV)-hepatitis C virus(HCV) related liver diseases. A systematic computerbased search of published articles, according to the Preferred Reporting Items for Systematic reviews and Meta-Analysis Statement, was performed to identify relevant studies on usefulness of serum/plasma/urine mi RNAs, as noninvasive biomarkers for early detection of HBV and HCV-induced hepatocellular carcinoma(HCC) development, as well as for its prognostic evaluation. The used Medical Subject Headings terms and keywords were: 'HBV', 'HCV', 'hepatocellular carcinoma', 'micro RNAs', 'mi RNAs', 'diagnosis', 'prognosis', 'therapy', 'treatment'. Some serum/plasma mi RNAs, including mi R-21, mi R-122, mi-125a/b, mi R-199a/b, mi R-221, mi R-222, mi R-223, mi R-224 might serve as biomarkers for early diagnosis/prognosis of HCC, but, to date, not definitive results or well-defined panels of mi RNAs have been obtained. More well-designed studies, focusing on populations of different geographical areas and involving larger series of patients, should be carried out to improve our knowledge on the potential role of mi RNAs for HCC early detection and prognosis. | Sirio Fiorino Maria Letizia Bacchi-Reggiani Michela Visani Giorgia Acquaviva Adele Fornelli Michele Masetti Andrea Tura Fabio Grizzi Matteo Zanello Laura Mastrangelo Raffaele Lombardi Luca Di Tommaso Arrigo Bondi Sergio Sabbatani Andrea Domanico Carlo Fabbri Paolo Leandri Annalisa Pession Elio Jovine Dario de Biase | 2016 | World Journal of Gastroenterology2016，22，15： | 25 |
| 2 | Clinical features and natural history of cryptogenic cirrhosis compared to hepatitis C virus-related cirrhosis显示文摘AIM To characterize natural history of cryptogenic cirrhosis(CC) and compare its clinical features and outcomes to those of hepatitis C virus(HCV)-related cirrhosis.METHODS A prospective cohort of 102 consecutive patients at their first diagnosis of CC were enrolled in this study. The clinical data and outcomes were compared to an ageand Child-pugh class-matched cohort of 110 patients with HCV-related cirrhosis. Diagnosis of cirrhosis was based on compatible clinical and laboratory parameters, ultrasound/endoscopic parameters and, whenever possible, on histological grounds and transient elastography. All cases of cirrhosis without a definite etiology were enrolled in the CC group. The parameters assessed were:(1) severity of liver disease at the time of first diagnosis;(2) liver decompensation during follow-up;(3) hepatocellular carcinoma(HCC);(4) orthotopic liver transplantation; and(5) death. The independent associated factors were evaluated by multiple logistic regression analysis, and survival and its determinants by the Kaplan-Meier model, log-rank test and Cox regression.RESULTS At the first observation, median age was 66 and 65 years and male gender was 36% and 58% for CC and HCV cirrhosis, respectively. CC showed Child-pugh class A/B/C of 47%/31%/22%, respectively. Compared to HCV cirrhosis, CC exhibited a significantly higher prevalence of metabolic syndrome(12% vs 54%, respectively), overweight/obesity, high BMI, impaired glucose tolerance, high blood pressure, dyslipidemia, hyperuricemia, cardiovascular diseases, extrahepatic cancer, and gallstones. Over a median period of 42 mo of follow-up, liver decompensation, HCC development and death for CC and HCV-related cirrhosis were 60.8%, and 54.4%, 16.7% and 17.2%, 39.2% and 30%, respectively. The median survival was 60 mo for CC. Independent predictors of death were age and Childpugh class at diagnosis. CC showed an approximately twofold higher incidence of HCC in Child-pugh class A.CONCLUSION Undiagnosed nonalcoholic fatty liver disease has an etiologic role in CC that is associated with a poor prognosis, early HCC development, high risk of cardiovascular disease and extrahepatic cancer. | Luca Rinaldi Fabio Nascimbeni Mauro Giordano Chiara Masetti Barbara Guerrera Annalisa Amelia Maria Chiara Fascione Stefano Ballestri Dante Romagnoli Rosa Zampino Riccardo Nevola Enrica Baldelli Natalina Iuliano Valerio Rosato Amedeo Lonardo Luigi Elio Adinolfi | 2017 | World Journal of Gastroenterology2017，23，8： | 5 |
| 3 | Intermittent gastric outlet obstruction due to a gallstone migrated through a cholecysto-gastric fistula:A new variant of “Bouveret’s syndrome”显示文摘Bouveret's syndrome, defined as gastric outlet obstruction due to a large gallstone, is still one of the most dramatic biliary gallstone complications. Although new radiological and endoscopic techniques have made pre-surgical diagnosis possible in most cases and the death rate has dropped dramatically, 'one-stage surgery' (biliary surgery carried out at the same time as the removal of the gut obstruction) should be still considered as the gold standard for the treatment of gallstone ileus.In this case, partial gastric outlet obstruction resulted in an atypical and insidious clinical presentation that allowed us to perform the conventional one-stage laparatomic procedure that completely solved the problem, thus avoiding any further complications. | Dimitry Arioli Ivo Venturini Michele Masetti Elisa Romagnoli Antonella Scarcelli Pietro Ballesini Athos Borghi Alessandro Barberini Vincenzo Spina Mario De Santis Fabrizio Di Benedetto Giorgio Enrico Gerunda Maria Luisa Zeneroli | 2008 | World Journal of Gastroenterology2008，14，1： | 2 |
| 4 | Hepatitis B and C virus infections as possible risk factor for pancreatic adenocarcinoma显示文摘 | S. Fiorino S. Lorenzini M. Masetti G. Deleonardi A.G. Grondona T. Silvestri E. Chili P. Del Prete L. Bacchi-Reggiani A. Cuppini E. Jovine | 2012 | Medical Hypotheses2012，，5： | 2 |
| 5 | The impact of extent of pancreatic and venous resection on survival for patients with pancreatic cancer显示文摘Background:Borderline resectable pancreatic cancer may require extended resections in order to achieve tumor-free margins,especially in the case of up-front resections,but it is important to know the limits of surgical therapy in this disease.This study aimed to investigate the impact of extent of pancreatic and venous resection on short-and long-term outcomes in patients with pancreatic adenocarcinoma(PDAC).Methods:This was a retrospective study from a prospectively maintained database of pancreatic resections for PDAC.Short-and long-term outcomes were analyzed in patients having borderline resectable PDAC submitted to up-front total pancreatectomy(TP)or pancreaticoduodenectomy(PD)with simultaneous portal vein(PV)and/or superior mesenteric vein(SMV)resection.Venous resections were carried out as tangential venous resection(TVR)or segmental venous resection(SVR).Patients were divided into 4 groups:(1)PD+TVR,(2)PD+SVR,(3)TP+TVR,(4)TP+SVR.Uni-and multivariate Cox regression analysis were performed to identify factors associated with survival.Results:Ninety-nine patients were submitted to simultaneous pancreatic and venous resection for PDAC.Among them,25 were submitted to PD+TVR(25.3%),12 to PD+SVR(12.1%),23 to TP+TVR(23.2%),and 39 to TP+SVR(39.4%).Overall,major morbidity(Clavien-Dindo grade≥IIIA)was 26.3%.Thirty-and 90-day mortality were 3%and 11.1%,respectively.There were no significant differences among groups in terms of short-term outcomes.Median overall survival of patients submitted to PD+TVR was significantly higher than those to TP+SVR(29.5 vs 7.9 months,P=0.001).Multivariate analysis identified TP(HR=2.11;95%CI:1.31–3.44;P=0.002)and SVR(HR=2.01;95%CI:1.27–3.15;P=0.003)as the only independent prognostic factors for overall survival.Conclusions:Up-front TP associated to SVR was predictive of worse survival in borderline resectable PDAC.Perioperative treatments in high-risk surgical groups may improve such poor outcomes. | Matteo Serenari Giorgio Ercolani Alessandro Cucchetti Matteo Zanello Enrico Prosperi Guido Fallani Michele Masetti Raffaele Lombardi Matteo Cescon Elio Jovine | 2019 | Hepatobiliary & Pancreatic Diseases International2019，18，4： | 2 |
| 6 | Modeling of Carrier Mobility Against Carrier Concentration in Arsenic Boron-doped Silicon显示文摘 | Masetti G Severi M Solmi S | 1983 | IEEE Transactions on Electronic Devices1983，30，7： | 1 |
| 7 | Slurry wall containment performance: monitoring and modeling of unsaturated and saturated flow显示文摘 | Daniele Pedretti Marco Masetti Tomaso Marangoni Giovanni Pietro Beretta | 2012 | Environmental Monitoring and Assessment2012，，2： | 1 |
| 8 | Vitellin degradation in developing embryos of the stick insect Carausius morosus 显示文摘 | Masetti M Giorgi F | 1989 | J Insect Physiol1989，35，： | 1 |
| 9 | Long-term survival and function of intrahepatic islet allografts in rhesus monkeys treated with humanized anti-CD154 显示文摘 | Kenyon NS Chatzipetrou M Masetti M | 1999 | Proc Natl Acad Sci USA1999，96，14： | 1 |
| 10 | Pancreatic resection for periampullary cancer in elderly patients显示文摘 | Magistrelli P Masetti R Coppola R | 1988 | Hepatogastroenterology1988，45，19： | 1 |
| 11 | Oncoplastic approachesto partial mastectomy : an overview of volume-displacement tech-niques显示文摘 | Anderson BO Masetti R Silverstein MJ | 2005 | Lancet Oncol2005，6，3： | 1 |
| 12 | Oncoplastic approaches to partial mastectomy:an overview of volume- displacement techniques显示文摘 | Anderson BO Masetti R Silverstein M J | 2005 | The lancet oncology2005，6，3： | 1 |
| 13 | Core-binding factor acutemyeloid leukemia in pediatric patients enrolled in the AIEOP AML2002/01 trial:screening and prognostic impact of c-KIT mutations显示文摘 | Manara E Bisio V Masetti R | 2014 | Leukemia2014，28，5： | 1 |
| 14 | Rare earth in limestone/marlstone couplets from the Albian-Cenomanian Cismon section(Venetian region,Northern Italy):assessing REE sensitiveity to environmental changes显示文摘 | BELLANCA A MASETTI D NERI R | 1997 | Chemical Geology1997，141，： | 1 |
| 15 | High-speed high-capacity packet-switching fabric a key system for required flexibility and capacity显示文摘 | Masetti F Chiaroni D Dragnea R | 2003 | Journal of Optical Networking2003，2，7： | 1 |
| 16 | Pediatric early T-cell precursor leukemia with NF1 deletion and high-sensitivity in vitro to tipifarnib 显示文摘 | Biagi C Astolfi A Masetti R | 2010 | Leukemia2010，24，6： | 1 |
| 17 | Spatial and statistical assessment of factors influencing nitrate contamination in groundwater显示文摘 | MASETTI M POLI S STERLACCHINI S | 2008 | Journal of Environmental Management2008，86，1： | 1 |
| 18 | Aberrant subclavian artery and Kommerell aneurysm: surgical treatment with a standard approach 显示文摘 | Kouchoukos NT Masetti P | 2007 | J thorac Cardiovasc Surg2007，133，4： | 1 |
| 19 | Liver transplantation from donors aged 80 years and over:pushing the limit显示文摘 | Nardo B Masetti M Urbani L | 2004 | Am J Transplant2004，4，7： | 1 |
| 20 | Status epilepticus as a main manifestation of posterior reversible encephalopathy syndrome after pediatric hematopoietic stem cell transplantation显示文摘 | Cordelli DM Masetti R Bernardi B | | 0，，05： | 1 |
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