|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | 高纤维膳食和补充乙酸盐改变肠道菌群,预防醋酸脱氧皮质酮-盐型高血压小鼠高血压和心力衰竭的发展显示文摘水果和蔬菜的膳食摄入与高血压的发生率较低有关,但所涉及的机制尚未阐明。该研究评估了高纤维膳食和短链脂肪酸(short-chain fatty acid,SCFA)(乙酸盐)对肠道微生物群和预防心血管病的影响。方法:用盐皮质激素诱发小鼠高血压模型,观测正常喂食组、高纤维喂食组和补充乙酸盐组的肠道微生物、心脏结构/功能和血压水平。 | 刘莉 叶鹏 Marques FZ Nelson EM Chu PY Horlock D Fiedler A Ziemann M Tan JK Kuruppu S Rajapakse NW El-Osta A Mackay CR Kaye DM | 2016 | 中华高血压杂志2016，24，12： | 8 |
| 2 | Chronic myeloid leukemia-from the Philadelphia chromosome to specific target drugs:A literature review显示文摘Chronic myeloid leukemia(CML)is a myeloproliferative neoplasm and was the first neoplastic disease associated with a well-defined genotypic anomaly―the presence of the Philadelphia chromosome.The advances in cytogenetic and molecular assays are of great importance to the diagnosis,prognosis,treatment,and monitoring of CML.The discovery of the breakpoint cluster region(BCR)-Abelson murine leukemia(ABL)1 fusion oncogene has revolutionized the treatment of CML patients by allowing the development of targeted drugs that inhibit the tyrosine kinase activity of the BCR-ABL oncoprotein.Tyrosine kinase inhibitors(known as TKIs)are the standard therapy for CML and greatly increase the survival rates,despite adverse effects and the odds of residual disease after discontinuation of treatment.As therapeutic alternatives,the subsequent TKIs lead to faster and deeper molecular remissions;however,with the emergence of resistance to these drugs,immunotherapy appears as an alternative,which may have a cure potential in these patients.Against this background,this article aims at providing an overview on CML clinical management and a summary on the main targeted drugs available in that context. | Mariana Miranda Sampaio Maria Luísa Cordeiro Santos Hanna Santos Marques Vinícius Lima de Souza Gonçalves Glauber Rocha Lima Araújo Luana Weber Lopes Jonathan Santos Apolonio Camilo Santana Silva Luana Kauany de SáSantos Beatriz Rocha Cuzzuol Quézia Estéfani Silva Guimarães Mariana Novaes Santos Breno Bittencourt de Brito Filipe Antônio França da Silva Márcio Vasconcelos Oliveira Cláudio Lima Souza Fabrício Freire de Melo | 2021 | World Journal of Clinical Oncology2021，12，2： | 3 |
| 3 | Anti-angiogenic therapies for metastatic colorectal cancer:Current and future perspectives显示文摘Colorectal cancer(CRC)is the fourth most commonly diagnosed cancer and the second leading cause of cancer death in both men and women in the United States,with about 142820 new cases and 50830 deaths expected in 2013.Metastatic disease(mCRC)remains a challenge for oncologists worldwide due to its potential comorbidities.Recently,chemotherapy regimens containing 5-fluorouracil,leucovorin,oxaliplatin and irinotecan combinations are a standard of care in the metastatic disease.Currently,biological therapies involving vascular endothelial growth factor and epidermal growth factor receptor pathways,such as bevacizumab and cetuximab,have emerged as good option for improving mCRC patient survival.Now,aflibercept plus standard chemotherapy has also been approved in second line regimen for mCRC patients.Our review will discuss novel biological drugs and their indications for mCRC patients and will bring future perspectives in this regard. | Inês Marques António Araújo Ramon Andrade de Mello | 2013 | World Journal of Gastroenterology2013，19，44： | 3 |
| 4 | Carrying capacity in the tourism industry: a case study of Hengistbury Head显示文摘 | Fernando J.Garrigós Simón Yeamduan Narangajavana Daniel Palacios Marqués | 2003 | Tourism Management2003，，2： | 2 |
| 5 | Modulation of the cellular immune response by a carbohydrate rich fraction from Echinococcus granulosus protoscoleces in infected or immunized Balb/c mice 显示文摘 | Dematteis S Pirotto F Marques J | 2001 | Parasite Immunol2001，23，1： | 1 |
| 6 | Detection and confirmation of chloramphenicol in milk by high performance liquid chromatography-tandem mass spectrometry 显示文摘 | Nicolich R S Werneck-Barroso E Sipoli Marques M A | 2006 | Analytica Chimica Acta2006，565，： | 1 |
| 7 | Low temperature synthesis of an- orthite based glass-ceramics via sintering and crystalli- zation of glass-powder compaets显示文摘 | MARQUES V M F TULYAGANOV D U AGATH- OPOULOS S | 2006 | J Eur Ceram Soc2006，26，13： | 1 |
| 8 | Traumatic experiences in individuals with body dysmorhphic disorder显示文摘 | Buhlmann U Marques LM Wilhelm S | 2012 | The Journal of Nervous and Mental Disorder2012，200，1： | 1 |
| 9 | Antinociceptive effect on mice of the hydroalcoholic fraction and (-) epicatechin obtained from Combretum leprosum Mart & Eich显示文摘 | Lopes L Marques R Pereira S | 2010 | Braz J Med Biol Res2010，43，12： | 1 |
| 10 | Modelling of anethanol-water distillation column assisted by an external heat pump显示文摘 | Oliveira S B M Parise J A R Pitanga Marques R | 2002 | International Journal of Energy Research2002，26，12： | 1 |
| 11 | 显示文摘 | | 1999 | Microporous Mesoporous Mater1999，32，12： | 1 |
| 12 | In vitro response of the brown bullhead catfish( BB ) and rainbow trout( RTG-2 ) cell lines to benzo pyrene 显示文摘 | Araujo C S A Marques S A F Carrondo M J T | 2000 | Science of the Total Environment2000，247，2： | 1 |
| 13 | Simple and rapid method determination for metformin in human plasma using high performance liquid chromatography tandem mass spectrometry: application to pharmacokinetic studies 显示文摘 | S'lpoli Marques M A Soares A S Pinto O W | 2007 | Chromatography B2007，852，： | 1 |
| 14 | Kovats retention indexes of monounsaturated C12, C14, and C16 alcohols, acetates and aldehydes commonly found in lepidopteran pheromone blends显示文摘 | MARQUES F A MCELFRESH J S MILLAR J G | 2000 | Braz Chem Soc2000，11，6： | 1 |
| 15 | Carbonic anhydrase inhibitots:Inhibition of cytosolic/tumor-associated isoforms Ⅰ,Ⅱ,and Ⅸ with iminodiacetic carboxylates/hydroxamates also incorporating benzenesulfonamide moieties显示文摘 | SANTOS MA MARQUES S VULLO D | 2007 | Bioorg Med Chem Lett2007，17，6： | 1 |
| 16 | Using middle level features for robust shape tracking 显示文摘 | NASCIMENTO J C ABRANTES A J MARQUES J S | 2003 | Pattern Recognition Letters2003，24，13： | 1 |
| 17 | Microglial cells initiate vigorous yet non-protective immune responses during HSV 1 brain infection 显示文摘 | Marques CP Hu S Sheng W | 2006 | Virus Res2006，121，1： | 1 |
| 18 | Validation of the determination of oxymetholone in human plasma analysis using gas chromatography-mass spectrometry Application to pharmacokinetic studies显示文摘 | Cardoso G R Marlice A Marques S | 2002 | Journal of Chromatography B2002，775，1： | 1 |
| 19 | Polypropylene degra- dation : Theoretical and experimental investigations 显示文摘 | Bertin D Leblanc M Marque S R A | 2010 | Polym Degrad Stab2010，95，5： | 1 |
| 20 | The effect of high-fat diet on rat's mood, feeding behavior and response to stress 显示文摘 | Aslani S Vieira N Marques F | 2015 | Transl Psychiatry2015，5，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员