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457篇 您的检索式:作者名="Mark Y"
    题名 作者 年代 出处 被引量
1Schistosoma mansoni proteins attenuate gastrointestinal motility disturbances during experimental colitis in mice显示文摘AIM:To investigate the therapeutic effect of Schistosoma mansoni(S.mansoni) soluble worm proteins on gastrointestinal motility disturbances during experimental colitis in mice. METHODS:Colitis was induced by intrarectal injection of trinitrobenzene sulphate(TNBS) and 6 h later,mice were treated ip with S.mansoni proteins.Experiments were performed 5 d after TNBS injection.Inflammationwas quantified using validated inflammation parameters. Gastric emptying and geometric center were measured to assess in vivo gastrointestinal motility.Peristaltic activity of distal colonic segments was studied in vitro using a modified Trendelenburg set-up.Cytokine profiles of T-lymphocytes isolated from the colon were determined by real time reverse transcriptase-polymerase chain reaction. RESULTS:Intracolonic injection of TNBS caused severe colitis.Treatment with S.mansoni proteins significantly ameliorated colonic inflammation after 5 d.TNBS did not affect gastric emptying but significantly decreased the geometric center and impaired colonic peristaltic activity 5 d after the induction of colitis.Treatment with S.mansoni proteins ameliorated these in vivo and in vitro motility disturbances.In addition,TNBS injection caused a downregulation of effector T cell cytokines after 5 d,whereas a S.mansoni protein effect was no longer observed at this time point. CONCLUSION:Treatment with S.mansoni proteins attenuated intestinal inflammation and ameliorated motility disturbances during murine experimental colitis.Nathalie E Ruyssers Benedicte Y De Winter Joris G De Man Natacha D Ruyssers Ann J Van Gils Alex Loukas Mark S Pearson Joel V Weinstock Paul A Pelckmans Tom G Moreels 2010World Journal of Gastroenterology2010,16,6:11
2Radiation activates HIF-1 to regulate vascular radiosensitivity in tumors显示文摘Benjamin J Moeller Yiting Cao Chuan Y Li Mark W Dewhirst 2004Cancer Cell2004,,5:2
3Immunostimulatory DNA sequences necessary for effective intraderlmal gene immunization显示文摘Snato Y Mark R Helen T 1996Science1996,273,:1
4Helicobacter pylori seropos- itivity andsubsite-speeifie gastric cancer risks in Linxian,China 显示文摘Limburg P Qiao Y Mark S 2001J Natl Cancer Inst2001,93,3:1
5Effects of antiagglomerants on the interactions between hydrate particles显示文摘Mark R A J Dalton Y Luke H 2007American Institute of Chemical Engineers2007,54,2:1
6Apoptotic and autophagic cell death induced by histone deacetylase inhibitors显示文摘Shao Y Gao Z Marks PA 2004Proc Natl Acad Sci USA2004,101,18:1
7The novel DPP-4 inhibitors linagliptin and BI 14361 reduce infarct size after mvocardial ischemia/reperfusion in rats显示文摘Hocher B Sharkovska Y Mark M 2013Int J Cardiol2013,167,:1
8PCA3 molecular urine assay for prostate cancer in men undergoing repeat biopsy 显示文摘Marks LS Fradet Y Deras IL 2007Urology2007,69,:1
9MRx102,a triptolide derivative,has potent antileukemic activity in vitro and in a murine model of AML显示文摘Carter BZ Mark DH Shi Y 2012Leukemia2012,26,3:1
10显示文摘 Marks T 1997J Organometallics1997,16,:1
11Exposure to gestational diabetes mellitus and low socioeconomic status:effects on neurocognitive development and risk of attention-deficit/hyperactivity disorder in offspring显示文摘Nomura Y Marks D J Grossman B 2012Arch Pediatr Adolesc Med2012,166,:1
12Combustion characteristics of coal in a mixture of oxygen and recycled flue gas显示文摘Tan Y Croiset E Mark A 2006Fuel2006,85,4:1
13Educating students with TBI: Themes and recommendations显示文摘Mark Y Bonnie T Ann G 2001The Journal of Head Trauma Rehabilitation2001,16,1:1
14The novel DPP-4 inhibitors linagliptin and BI 14361 reduce infarct size after myocardial ischemia/reperfusion in rats显示文摘Hocher B Sharkovska Y Mark M 2013Int j Cardiol2013,167,1:1
15Enhancement of thermal conductivity with Cu for nanofluids using chemical reduction method显示文摘Liu Minsheng Lin Mark Chingcheng Tsai C Y 2006International Journal of Heat and Mass Transfer2006,49,:1
16Changes in interagraft gene expression secondary to ischemia reperfusion after cardiac transplantation显示文摘MARK D STEGALL WALTER D PARK DEAN Y KIM 2002Transplantation2002,74,:1
17U ntangling the ErbB signaling network 显示文摘Yosef Y Mark X Sliwkows K I 2001Nature Rev2001,2,2:1
18SUN: A Bayesianframework for saliency using natural statistics显示文摘Zhang L Y Tong M H Marks T K 2008Journal ofVision2008,8,7:1
19Adsorption,sequestration,and bioaccessibility of As(V)in soils显示文摘JAE K Y MARK O B PHILIP M J 2002EnvironSci Technol2002,36,21:1
20Perceptualcognitive expertise in sport: a meta-analysis显示文摘DLEREK T Y MANN A MARK WILLIAMS 2007J Sport Psychol2007,29,:1
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