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| 1 | Nat Biotechnol:将人星形胶质细胞重编程为多巴胺能神经元,有助治疗帕金森病显示文摘帕金森病是一种主要影响运动系统的神经退行性疾病。它的特征在于大脑中的多巴胺能神经元(dopaminergic neuron)渐进性丧失。尽管当前的疗法旨在补充多巴胺水平,但是没有一种疗法能够恢复这些丢失的细胞。如今。在一项新的研究中,来自瑞典、奥地利、西班牙和美国的研究人员开发出一种方法:将神经胶质细胞(glialcell)转化为活性的多巴胺能神经元,并且所产生的多巴胺能神经元能够部分恢复帕金森病模式小鼠的运动功能。这项概念验证研究可能为开发出一种治疗这种疾病的新方法铺平道路。 | Pia Rivetti di Val Cervo, Elisa Martín-Montañez, Enrique M Toledo, Gioele La Manno, Sara Padrell Sánchez, Sten Linnarsson Ernest Arenas Roman A Romanov, Christian Pifl Tibor Harkany Roman A Romanov, Giada Spigolon, Débora Masini, Michael Feyder, Tibor Harkany Gilberto Fisone Elisa Martín-Montañez Yi-Han Ng Marius Wernig | 2017 | 现代生物医学进展2017,17,17: | 11 |
| 2 | Ecosystem services and legal protection of private property.Problem or solution?显示文摘Ecosystem services(ES)delivery in quantity and quality are essential to improve human wellbeing.Nevertheless,often a considerable part of ES provisioning depends on the use of private land(e.g.,flood retention,carbon sequestration,water purification).In this context,the operationalization and implementation of ES concept may collide with legal property rights.Therefore,it is essential to find constructive mechanisms to engage and encour-age private owners to implement sustainable land uses to reduce the onsite and offsite impacts of their activities.This paper aims to identify if ES delivery can be constrained by legal private land and how it can be tackled.It is undeniable that land-use changes(e.g.,urbanization,agriculture intensification,and land abandonment)affect the territory’s capacity to deliver ES in quality and quantity.These changes,especially land abandonment,are in-creasing the tradeoffs among ES(e.g.,between carbon sequestration and water yield).Land-use planning should consider these aspects.Therefore,incorporating ES into spatial plans is crucial for stakeholders to understand the impacts of land-use change in the loss of ES value.This information can be transmitted through maps that communicate the message in a simplified way.Private owners can easily perceive the ES relevance that their land can provide if an understandable message is delivered.Although this can be a good solution,conflicts can appear even with the implementation of schemes such as Payment for ES(PES).PES is not always effective and can im-pose losses to farmers,disregard their cultural traditions,or not prevent poverty alleviation.In this context,it is crucial to consider local specificities to safeguard PES’s success,create a“win-win”and transform a problem into a solution.Private owners’active participation in implementing sustainable practices or a determined land-use in their properties is vital to achieving global targets such as sustainable development goals. | Katažyna Mikša Marius Kalinauskas Miguel Inácio Eduardo Gomes Paulo Pereira | 2020 | Geography and Sustainability2020,1,3: | 2 |
| 3 | Seetoral agglomeration economies in a panel of European regions 显示文摘 | Marius Balhart Nieole A Mathys | 2008 | Regional Sci- ence and Urban Economics2008,38,4: | 1 |
| 4 | Three-Dimensional Imaging Laser Radars with Geiger-Mode Avalanche Photodiode Arrays显示文摘 | Marius A Albota Brian F Aull Daniel G Fouche | 2002 | LINCOLN LABORATORY JOURNAL2002,13,: | 1 |
| 5 | Three-dimensional imaging laser radars with Geiger-mode avalanche photodiode arrays 显示文摘 | Albota Marius A Aull Brian F Fouche Daniel G | 2002 | Lincoln Laboratory Jour- nal2002,13,2: | 1 |
| 6 | Correlation of plasma van Willebrand factor levels, an index of endothelial damage/dys- function, with two point-based stroke risk stratification scores in atri- al fibrillation 显示文摘 | Roldan V Mariu F Gareia-Herola A | 2005 | Thromb Res2005,116,4: | 1 |
| 7 | Estimating parameters of multiple wideband polynomial-phase sources in sensors arrays显示文摘 | GERSHMAN A B MARIUS AMIN M G | 2001 | IEEE Trans Signal Processing2001,49,12: | 1 |
| 8 | Impact of prostaglandin-F2a-analogues and carbonic anhydrase inhibitors on central corneal thickness-a cross-sectional study on 403 eyes显示文摘 | Viestenz A Marius P Schl(o)tzer-Schrehardt U | 2004 | Klin Monatsbl Augenheilkd2004,221,9: | 1 |
| 9 | Estimating pa-rameters of multiple wideband polynomial-phasesources in sensors array显示文摘 | Gershman A B Marius Amin M G | 2001 | IEEE Trans on SignalProcessing2001,,12: | 1 |
| 10 | Two-state semiconductor laser selfmixing velocimetry exploiting coupled quantum-dot emission-states:Experiment,simulation and theory显示文摘 | Mari A G Marius D | 2014 | Optics Express2014,22,23: | 1 |
| 11 | The fate of heterotopically grafted neural precursor cells in the normal and dystrophic adult mouse retina显示文摘 | Susanne P Marius A Gisbert R Melitta S Udo B | 2001 | Invest Ophthalmol Vis Sci2001,42,13: | 1 |
| 12 | Robert S Rosenson Statins and sepsis:multiple modifi cations at multiple levels显示文摘 | Marius T Yaniv A | 2007 | Lancet Infect Dis2007,7,5: | 1 |
| 13 | Three-Dimensional imaging laser radar swith gei- get-mode avalanche photodiode arrays 显示文摘 | Marius A Albota Brian F Aull Daniel G Fouche | 2002 | Lincoln Laboraory Journal2002,13,2: | 1 |
| 14 | Whole slide images as a platform for initial diagnostics in histopathol- ogy in a medium-sized routine laboratory显示文摘 | Shaimaa A J Andr6 H Marius N | 2012 | Journal of Clinical Pathology2012,65,12: | 1 |
| 15 | Generation of efficient human blood progenitor-targeted recombinant adeno-associated viral vectors (AAV) by applying an AAV random peptide library on primary human hematopoietic progenitor cells显示文摘 | Leopold S Marius S Jiirgen A K | 2008 | Experimental Hematology2008,36,8: | 1 |
| 16 | Decay rates for a beam with pointwise force and moment feedback 显示文摘 | KAIS A LIU Zhuangyi MARIUS T | 2002 | Mathematics of Control Signals and Systems2002,15,2: | 1 |
| 17 | Weaning and the weaning diet influence the villous height and crypt depth in the small intestine of pigs and al- ter the concentrations of short-chain fatty acids in the large intestine and blood显示文摘 | Hatty M G Van B Marius J A nabaurs | 1998 | J Nutr1998,128,: | 1 |
| 18 | Brain aromatase in Japanese medaka (Oryzias latipes) : Molecular characterization and role in xenoestrogen-induced sex reversal 显示文摘 | kuhl a j steve m marius b | 2005 | Journal of Steroid Biochemistry and Molecular Biology2005,96,1: | 1 |
| 19 | The effect of monetary policy on real house price growth in South Mrica:Afactor - augmented vector autoregressin ( FAVAR ) approach 显示文摘 | Gupta B Marius J Kabundi A | 2010 | Economic Modelling2010,27,: | 1 |
| 20 | The effect of monetary policy on real house price growth in south africa: A fac- tor - augmented vector auto - regression ( FAVAR ) Ap- proach 显示文摘 | Gupta R Marius J Kabundi A | 2010 | Economic Modeling2010,,: | 1 |