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| 1 | E-waste environmental contamination and harm to public health in China显示文摘人的身体上的电子废物(电子浪费) 的不利效果在最近的年里煽动了担心。中国是面对严肃的污染和电子浪费的人的暴露的国家之一,并且人口的多数暴露于从再循环过程的非正式的电子浪费被导出的潜在地危险的物质。这研究在中国在人的暴露上考察最近的报告到电子浪费,与暴露线路的特别焦点(例如,吸入和摄取) 并且人的几毒性(例如,内分泌的系统,呼吸系统,繁殖系统,发展毒性, neurotoxicity,和基因毒性) 。一些有在中国的人的健康效果的伙伴电子浪费暴露被估计的证据。有毒的重金属的角色(例如,铅,镉,铬,水银,和镍)并且器官的污染物质(例如, polybrominated diphenyl 醚( PBDE ), polychlorinated 联本基(印刷电路板),多不的芳香的烃(哼), polybrominated 联本基( PBB ), polyhalogenated 芳香的烃( PHAH ), bisphenol A ( BPA ))在人上,健康简短也被讨论。 | Xijin Xu Xiang Zeng H. Marike Boezen Xia Huo | 2015 | Frontiers of Medicine2015，9，2： | 6 |
| 2 | Tacrolimus and mycophenolate mofetil as second-line treatment in autoimmune hepatitis:Is the evidence of sufficient quality to develop recommendations?显示文摘BACKGROUND The standard management of autoimmune hepatitis(AIH)is based on corticosteroids,alone or in combination with azathioprine.Second-line treatments are needed for patients who have refractory disease.However,high-quality data on the alternative management of AIH are scarce.AIM To evaluate the efficacy and safety of tacrolimus and mycophenolate mofetil(MMF)and the quality of evidence by using the Grading of Recommendations Assessment,Development and Evaluation approach(GRADE).METHODS A systematic review and meta-analysis of the available data were performed.We calculated pooled event rates for three outcome measures:Biochemical remission,adverse events,and mortality,with their corresponding 95%confidence intervals(CI).RESULTS The pooled biochemical remission rate was 68.9%(95%CI:60.4-76.2)for tacrolimus,and 59.6%(95%CI:54.8-64.2)for MMF,and rates of adverse events were 25.5%(95%CI:12.4-45.3)for tacrolimus and 24.1%(95%CI:15.4-35.7)for MMF.The pooled mortality rate was estimated at 11.5%(95%CI:7.1-18.1)for tacrolimus and 9.01%(95%CI:6.2-12.8)for MMF.Pooled biochemical remission rates for tacrolimus and MMF in patients with intolerance to standard therapy were 56.6%(CI:43.4-56.6)vs 73.5%(CI:58.1-84.7),and among non-responders were 59.1%(CI:48.7-68.8)vs 40.8%(CI:32.3-50.0),respectively.Moreover,the overall quality assessments using GRADE proved to be very low for all our outcomes in both treatment groups.CONCLUSION Tacrolimus and MMF are in practice considered effective for patients with AIH who are non-responders or intolerant to first-line treatment,but we found no high-quality evidence to support this statement. | Mohammadreza Abdollahi Neda Khalilian Ekrami Morteza Ghojazadeh H Marike Boezen Mohammadhossein Somi Behrooz Z Alizadeh | 2020 | World Journal of Gastroenterology2020，26，38： | 5 |
| 3 | Dynamic changes in arterial waveform derived variables and fluid responsiveness in mechanically ventilated patients: A systematic review of the literature显示文摘 | Paul E. Marik Rodrigo Cavallazzi Tajender Vasu Amyn Hirani | 2009 | Critical Care Medicine2009，，9： | 2 |
| 4 | The hemodynamic management of elderly patients with sepsis显示文摘Sepsis is among the most common reason for admission to intensive care units throughout the world. In the US and most Western nations sepsis is largely a disease of the elderly. Management of elderly patients with severe sepsis is challenging. Early recognition of this syndrome, together with the early administration of appropriate antibiotics and cautious fluid resuscitation is the cornerstone of therapy. Echocardiography together with non-invasive or invasive hemodynamic monitoring is recommended in patients who have responded poorly to fluids or have significant underlying cardiac disease. This paper reviews the hemodynamic changes that characterize sepsis, particularly as they apply to elderly patients and provides recommendations for the management of these patients. | Paul E. Marik Joseph Varon | 2007 | Journal of Geriatric Cardiology2007，4，2： | 2 |
| 5 | Stress ulcer prophylaxis in the new millennium: A systematic review and meta-analysis显示文摘 | Paul E. Marik Tajender Vasu Amyn Hirani Monvasi Pachinburavan | 2010 | Critical Care Medicine2010，，11： | 2 |
| 6 | Early enteral nutrition in acutely ill patients: A systematic review显示文摘 | Paul E. Marik Gary P. Zaloga | 2001 | Critical Care Medicine2001，，12： | 2 |
| 7 | Does central venous pressure predict fuid responsiveness显示文摘 | MARIK PE BARAM M VAHID B | 2008 | CHEST2008，134，1： | 1 |
| 8 | Bench-to-bedside review:Rhabdomyolysis:an overview for clinicians显示文摘 | Huerta-Alardín AL Varon J Marik PE | 2005 | Crit Care2005，9，2： | 1 |
| 9 | Near fatal posterior reversible encephalopathy syndrome complicating chronic liver failure and treated by induced hypothermia and dialysis:a case report显示文摘 | Chawla R Smith D Marik PE | 2009 | J Med Case Rep2009，3，： | 1 |
| 10 | Definition of sepsis: not quite time to dump SIRS? 显示文摘 | Marik PE | 2002 | Crit Care Med2002，30，3： | 1 |
| 11 | Bedside ultrasonography in the ICU:part 1显示文摘 | Beaulieu Y Marik PE | 2005 | Chest2005，128，： | 1 |
| 12 | Dynamic changes in arterial waveform derived variables and fluid responsiveness in mechanically ventilated patients:a systematic review of the literature显示文摘 | Marik P E Cavallazzi R Vasu T | | 0，，09： | 1 |
| 13 | Stress ulcer prophylaxis in the new millennium: A systematic review andmeta anal- ysis显示文摘 | Marik PE Vasu T Hirani A | 2010 | Crit Care Med2010，38，11： | 1 |
| 14 | What's new with hypertensive crises? 显示文摘 | Monnet X Marik P E | 2015 | Intensive Care Med2015，41，： | 1 |
| 15 | Early enteral nut rition in acutely illpatients;a systematic revien显示文摘 | Marik PE Zaloga GP | 2001 | Crit Care Med2001，29，12： | 1 |
| 16 | Hypertensive crises: challenges and management显示文摘 | MARIK P E VARON J | 2007 | Chest2007，131，6： | 1 |
| 17 | Aspiration pneumonitis and aspiration pneumonia显示文摘 | Marik PE | 2001 | N Engl J Med2001，344，： | 1 |
| 18 | Dominantly inherited progres- sive pseudorheumatoid dysplasia with hypoplastie toes显示文摘 | Marik I Marikova O Zemkova D | 2004 | Skeletal Radiol2004，33，3： | 1 |
| 19 | Stress-hyperglycemia, insulin and immunomodulation in sepsis显示文摘 | Marik PE Raghavan M | 2004 | Intensive Care Med2004，30，5： | 1 |
| 20 | Does central venous pressure predict fluid responsiveness A systematic review of the literature and the tale of seven mares 显示文摘 | Marik PE Baram M rabid B | 2008 | chest2008，134，1： | 1 |
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