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| 1 | 岩石断裂表面分形测量的尺度效应显示文摘分形几何用于定量描述复杂的自然现象和不规则物体已有许多成功的范例,如岩石断裂表面粗糙度的测量。然而,岩石断裂表面粗糙度一般不具有自相似分形性质。因此,表面分形测量结果受尺度的影响。通过对不同试件长度、测量尺规和测量仪器分辩率的实际测量结果,分析了岩石断裂表面分形测量中的尺度效应,提出了可靠的分形测量的途径。 | 王金安 谢和平 田晓燕 Kwasniewski Marek A | 2000 | 岩石力学与工程学报2000，19，1： | 55 |
| 2 | Significance of postoperative follow-up of patients with metastatic colorectal cancer using circulating tumor DNA显示文摘BACKGROUND One of the most notable applications for circulating tumor DNA(ctDNA)detection in peripheral blood of patients with metastatic colorectal cancer(mCRC)is a long-term postoperative follow-up.Sometimes referred to as a“liquid(re)biopsy”it is a minimally invasive procedure and can be performed repeatedly at relatively short intervals(months or even weeks).The presence of the disease and the actual extent of the tumor burden(tumor mass)within the patient’s body can be monitored.This is of particular importance,especially when evaluating radicality of surgical treatment as well as for early detection of disease progression or recurrence.AIM To confirm the radicality of surgery using ctDNA and compare available methods for detection of recurrence in metastatic colorectal cancer.METHODSA total of 47 patients with detected ctDNA and indications for resection of mCRC were enrolled in the multicenter study involving three surgical centers.Standard postoperative follow-ups using imaging techniques and the determination of tumor markers were supplemented by ctDNA sampling.In addition to the baseline ctDNA testing prior to surgery,a postoperative observation was conducted by evaluating ctDNA presence up to a week after surgery and subsequently at approximately three-month intervals.The presence of ctDNA was correlated with radicality of surgical treatment and the actual clinical status of the patient.RESULTS Among the monitored patients,the R0(curative)resection correlated with postoperative ctDNA negativity in 26 out of 28 cases of surgical procedures(26/28,93%).In the remaining cases of R0 surgeries that displayed ctDNA,both patients were diagnosed with a recurrence of the disease after 6 months.In 7 patients who underwent an R1 resection,4 ctDNA positivities(4/7,57%)were detected after surgery and associated with the confirmation of early disease recurrence(after 3 to 7 months).All 15 patients(15/15,100%)undergoing R2 resection remained constantly ctDNA positive during the entire follow-up period.In 22 cases of recurrence,ctDNA positivity was detected 22 times(22/22,100%)compared to 16 positives(16/22,73%)by imaging methods and 15 cases(15/22,68%)of elevated tumor markers.CONCLUSION ctDNA detection in patients with mCRC is a viable tool for early detection of disease recurrence as well as for confirmation of the radicality of surgical treatment. | Lucie Benešová Tereza Hálková Renata Ptáčková Anastasiya Semyakina Kateřina Menclová JiříPudil Miroslav Ryska Miroslav Levý JaromírŠimša Filip Pazdírek JiříHoch Milan Blaha Marek Minárik | 2019 | World Journal of Gastroenterology2019，25，48： | 3 |
| 3 | Shoot and root traits in drought tolerant maize(Zea mays L.) hybrids显示文摘This study aimed to investigate the differences in shoot and root traits, and water use and water use efficiency(WUE) in drought tolerant(DT) maize(Zea mays L.) hybrids under full and deficit irrigated conditions. A two-year greenhouse study was conducted with four hybrids(one conventional hybrid, 33D53AM, two commercial DT hybrids, P1151 AM, N75H, and an experimental hybrid, Exp HB) grown under two water regimes(I_(100) and I_(50), referring to 100 and 50% of evapotranspiration requirements). Under water stress, the hybids P1151 AM, N75, and Exp HB showed more drought tolerance and had either greater shoot dry weight or less dry weight reduction than the conventional hybrid(33 D53 AM). However, these three hybrids responded to water stress using different mechanisms. Compared with the conventional hybrid, the two commercial DT hybrids(P1151 AM and N75H) had a smaller leaf area, shoot dry weight, and root system per plant. As a result, these hybrids used less water but had a higher WUE compared with the conventional hybrid. In contrast, the experimental hybrid(ExpHB) produced more shoot biomass by silking stage at both irrigation levels than all other hybrids, but it had relatively lower WUE. The hybrids demonstrated different drought response mechanisms that may require different irrigation management strategies. More investigation and validation are needed under field conditions and in different soil types. | ZHAO Jin XUE Qing-wu Kirk E Jessup HOU Xiao-bo HAO Bao-zhen Thomas H Marek XU Wen-wei Steven R Evett Susan A O'Shaughnessy David K Brauer | 2018 | Journal of Integrative Agriculture2018，17，5： | 3 |
| 4 | Effect of Copper Content and Heat Treatment on the Stress Corrosion Characteristics of Al-6Zn- 2Mg-XCu Alloys显示文摘 | Sarkar B Marek M Starke E A Jr | 1981 | Metallurgical TransactionsA1981，12，11： | 1 |
| 5 | PERMANENT MAGNETS SYNCHRONOUS MOTOR CONTROL THEORY 显示文摘 | Marek Stulrajter Val'eria Hrabovcov'a | 2007 | Journal of ELECTRICAL ENGINEERING2007，58，2： | 1 |
| 6 | Temperature and Thickness Dependence of Steam Oxidation of AlAs in cylindrical Mesa structures显示文摘 | Marek Osinski Tengiz Svimonishvili Gennady A | 2001 | IEEE Photonics Technology Letters2001，13，7： | 1 |
| 7 | An autosomal recessive form of monilethrix is caused by mutations in DSG4: clinical overlap with localized autosomal recessive hypotrichosis 显示文摘 | Zlotogorski A Marek D Horev L | 2006 | J Invest Dermatol2006，126，6： | 1 |
| 8 | Levine On Critical Exponents for a Semilinear Parabolic System Coupled in an Equation and a Boundary Condition显示文摘 | Howard A | 1996 | J Math Anal Appl1996，204，： | 1 |
| 9 | The role of nireic oxide in portal hypertensive systemic and portal vascular pathology 显示文摘 | Harthb M Michielsen PP Dxiurkowska - Marek A | 1997 | Acta Gastroenterol Velg1997，，60： | 1 |
| 10 | The effect of copper content and heat treatment on the stress corrosion characteristics of A1-6Zn-2Mg-xCu alloys 显示文摘 | SARKAR B MAREK M STARKE E A | 1981 | Metallurgical and Materials Transactions A1981，12，11： | 1 |
| 11 | Antilipoxygen ase activity of compounds from Hypericum perfora- tum显示文摘 | MAREK O B LYDIA J HOLKOV A etal | 2006 | Section Celhiar Molecular Biology2006，61，3： | 1 |
| 12 | TGF-beta(transforming growth factor-beta) in chronic inflammatory conditions-a new diagnostic and prognostic marker 显示文摘 | Marek A Brodzicki J Liberek A et al | 2002 | Med Sci Monit2002，8，7： | 1 |
| 13 | Control of nitric oxide nitrous,oxide,and ammonia emissions using microwave plasmas显示文摘 | MAREK A W FRANCIS P M GRIMES R W | 2000 | Journal of Hazardous Materials2000，74，29： | 1 |
| 14 | Theory ofcore-collapse supemovae显示文摘 | Janka H Th Langanke K Marek A | 2007 | Physics Reports2007，442，： | 1 |
| 15 | An EducationalTheory Base For Science Teaching显示文摘 | Renner John W Marek Edmund A | 1990 | Journal of Research inScience Teaching1990，27，3： | 1 |
| 16 | The fate of nitrogen functionalities in coal during pyrolysis and combustion显示文摘 | Marek A Wo Jan R P Jacob A M | 1995 | Fuel1995，74，4： | 1 |
| 17 | Even young patients with no alarm symptoms should undergo endoscopy for earlier diagnosis of gastric cancer显示文摘 | BOLDYS H MAREK T A WANCZURA P | 2003 | Endoscopy2003，35，1： | 1 |
| 18 | Evaluation of the ruggedness of power DMOS transistor from electro-thermal simulation of UIS behaviour显示文摘 | DONOVAL D VRBICKY A MAREK J | 2008 | SSE2008，52，6： | 1 |
| 19 | Optical properties of platinum-coated gold nanorods 显示文摘 | Marek Grzelczak Jorge Pe'rez-Juste F Javier Garci'a de Abajo | 2007 | J Phys Chem C2007，111，： | 1 |
| 20 | The Protestant work eth- ic,expectancy violations,and criminal sentencing显示文摘 | Christopher A Marek P May J C | 2003 | Jour- nal of Applied Social Psychology2003，，3： | 1 |
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