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105篇 您的检索式:作者名="Marcel K"
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1Distinctive inflammatory bowel disease phenotype in primary sclerosing cholangitis显示文摘AIM:To review the current literature for the specificclinical characteristics of inflammatory bowel disease(IBD)associated with primary sclerosing cholangitis(PSC).METHODS:A systematical review for clinical characteristics of IBD in PSC was performed by conducting a broad search for'primary sclerosing cholangitis'in Pubmed.'Clinical characteristics'were specified into five predefined subthemes:epidemiology of IBD in PSC,characteristics of IBD in PSC(i.e.,location,disease behavior),risk of colorectal cancer development,IBD recurrence and de novo disease after liver transplantation for PSC,and safety and complications after proctocolectomy with ileal pouchanal anastomosis.Papers were selected for inclusion based on their relevance to the subthemes,and were reviewed by two independent reviewers.Only full papers relevant to PSC-IBD were included.Additionally the references of recent reviews for PSC(<5 years old)were scrutinized for relevant articles.RESULTS:Initial literature search for PSC yielded 4704results.After careful review 65 papers,comprising a total of 11406 PSC-IBD patients,were selected and divided according to subtheme.Four manuscripts overlapped and were included in two subthemes.Prevalence of IBD in PSC shows a large variance,ranging from 46.5%to 98.7%with ulcerative colitis(UC)being the most common type(>75%).The highest IBD rates in PSC are found in papers reviewing both endoscopic and histological data for IBD diagnosis.Although IBD in PSC is found to be a quiescent disease,pancolitis occurs often,with rates varying from 35%to 95%.Both backwash ileitis and rectal sparing are observed infrequently.The development of dysplasia or colorectal carcinoma is increased in PSC-IBD;the cumulative 10 years risk varying between 0%and11%.Exacerbation of IBD is common after liver transplantation for PSC and de novo disease is seen in1.3%to 31.3%of PSC-IBD patients.The risk for development of pouchitis in PSC-IBD is found to besignificant,affecting 13.8%to 90%of the patients after proctocolectomy with ileo anal-pouch anastomosis.CONCLUSION:IBD in primary sclerosing cholangitis represents a distinct phenotype that differs from UC and Crohn’s disease and therefore requires specialized management.A Boudewijn de Vries Marcel Janse Hans Blokzijl Rinse K Weersma 2015World Journal of Gastroenterology2015,21,6:17
2Effectiveness of Helicobacter pylori eradication in the treatment of early-stage gastric mucosa-associated lymphoid tissue lymphoma:An up-to-date meta-analysis显示文摘BACKGROUND Gastric mucosa-associated lymphoid tissue(MALT)lymphoma(GML)is usually a low-grade B-cell neoplasia strongly associated with Helicobacter pylori(H.pylori)-induced chronic gastritis.Clinical practice guidelines currently recommend H.pylori eradication as the preferred initial treatment for early-stage GML.To determine the practical effect of bacterial eradication as the sole initial therapy for early-stage GML,an updated analysis and review of available evidence is imperative.AIM To perform a meta-analysis to assess the rate of complete remission(CR)of H.pylori-positive early-stage GML following bacterial eradication.METHODS We performed independent,computer-assisted literature searches using the PubMed/MEDLINE,Embase,and Cochrane Central databases through September 2022.Prospective and retrospective observational studies evaluating the CR of early-stage GML following bacterial eradication in H.pylori-positive patients.The risk of bias was assessed using Joanna Briggs Institute(JBI)Critical Appraisal Tools.The pooled estimate of the complete histopathological remission rate and respective confidence intervals(95%CI)were calculated following the random-effects model.Heterogeneity and inconsistency were assessed using Cochran’s Q test and I2 statistic,and heterogeneity was defined as P<0.01 and I²>50%,respectively.Subgroup and meta-regression analyses were conducted to explore potential sources of heterogeneity.RESULTS The titles and abstracts of 1576 studies were screened;96 articles were retrieved and selected for full-text reading.Finally,61 studies were included in the proportional meta-analysis(P-MA).Forty-six were prospective and fifteen were retrospective uncontrolled,single-arm,observational studies.The overall risk of bias was low to moderate in all but a single report,with an average critical appraisal score across all studies of 79.02%.A total of 2936 H.pylori-positive early-stage GML patients,in whom H.pylori was successfully eradicated,were included in the analysis.The pooled CR of H.pylori-positive early-stage GML after bacterial eradication was 75.18%(95%CI:70.45%-79.91%).P-MA indicated the substantial heterogeneity in CR reported across studies(I2=92%;P<0.01).Meta-regression analysis identified statistically significant effect modifiers,including the proportion of patients with t(11;18)(q21;q21)-positive GML and the risk of bias in each study.CONCLUSION Comprehensive synthesis of available evidence suggests that H.pylori eradication is effective as the sole initial therapy for early-stage GML.Although the substantial heterogeneity observed across studies limits the interpretation of the pooled overall CR,the present study is a relevant to informing clinical practice.Fabian Fellipe Bueno Lemos Caroline Tianeze de Castro Mariana Santos Calmon Marcel Silva Luz Samuel Luca Rocha Pinheiro Clara Faria Souza Mendes dos Santos Gabriel Lima Correa Santos Hanna Santos Marques Henrique Affonso Delgado Kádima Nayara Teixeira Cláudio Lima Souza Márcio Vasconcelos Oliveira Fabrício Freire de Melo 2023World Journal of Gastroenterology2023,29,14:2
3一座传授木材技术的木建筑显示文摘在瑞士的汝拉山脚下,有一座人口约5万的小城市——比尔(Biel/Bienne),自19世纪起就一直拥有繁荣的工业和手表制造业。与这座城市的工业氛围相得益彰的,是充满实用精神的应用科学教育。所属于伯尔尼应用科学大学(Bern University of Applied Sciences)的比尔高等木材技术学校(Higher Technical School of Wood Biel,HTS)即坐落于这里。Marcel Meili Markus Peter Zeno Vogel Thomas Kühne Marc Loeliger Andreas Schmidt Thomas Schnabel Urs Schnenberger Othmar Villiger 2018世界建筑2018,,7:2
4Optimization of Mo/Cu(In,Ga)Se2/CdS/ZnO Hetero-Junction Solar Cell Performance by Numerical Simulation with SCAPS-1D显示文摘The paper presents a one-dimensional simulation study of chalcopyrite Cu(In,Ga)Se2(CIGS)solar cells,where the effects of the variation of CIGS,CdS,and ZnO layers are presented.Additionlly the influence of the variation of doping and the defects density of shallow uniform donors and acceptors types are also presented.The analyse of the simulation results shows that recombination inside the space charge region(SCR)decrease more our CIGS solar cell model performance.We also found that the electrical parameters increase with increasing CIGS absorber doping density exception of JSC values that reach their maximum at 1016cm-3 and decrease due to recombination of charge carriers in the p-n junction particularly the recombination inside the SCR.We also stressed the fact that the effects of shallow uniforme donor density is very low on the performance of our CIGS solar cell model is important because it will allow to control the width of space charge region from shallow uniform acceptors defect density that has a strong influence on the different electrical parameters.Yet,good optimization of performance of the CIGS-based solar cell necessarily passes though a good control of the space charge region width and will constitute a boosting perspective for the preparation of our next paper.We contact that the results obtained of the numerical simulation with SCAPS-1D show a good agreement comparatively of the literature results.The simulation of our CIGS solar cell presents best performances if the values of the absorber layer thickness is in the range of 0.02 to 0.03μm,the buffer layer thickness is in the range of 0.02 to 0.06μm and the defects density of shallow uniform acceptors types is in the range of 1015 to 1017cm-3.Adama Zongo Daouda Oubda Soumaïla Ouédraogo Marcel Bawindsom Kébré Alain Diasso Issiaka Sankara Boureima Traore François Zougmoré Zacharie Koalga Frédéric Ouattara 2021材料科学与工程(中英文B版)2021,11,4:2
5Adenomatous polyposis coli - mediated control of β - catenin is essential for both chondrogenic and osteogenic differentiation of skeletal precursors 显示文摘Razvan LM Marcel K Cathy A J 2009BMC Der Biol2009,9,:1
6Lipases in the Preparation of β-blockers 显示文摘 Vincent H M E van Lersel J 1988TIBTECH1988,6,:1
7Sedative and anticonvulsant activities of methanol extract of Dorstenia arifolia in mice 显示文摘GISELE Z S THAIANA C F M MARCELLE A K 2010Journal of Ethnopharmacology2010,130,:1
8Compaction of DNA by Gemini Surfactants:Effects of Surfactant Architecture显示文摘Lisa K Marcel C P Olle S 2002J Colloid Interface Sci2002,252,2:1
9Mechanics of toe and heel landing in stepping down in ongoing gait显示文摘Jaap H Marcel S Reinier K 2008Physical Therapy in Sport2008,41,:1
10Evidence for the semireduced primary quinone electron acceptor of photosystem II being a photosensitizer for UVB damage to be the photosynthetic apparatus 显示文摘GUSTAVO C R MARCEL A K JANSEN M E VAN DEN NOORT 2006Plant Science2006,170,:1
11Synthesis of the main metabolite(OL-17) of cyclosporin A显示文摘Marcel K E Francois N 1992J Org Chem1992,57,9:1
12Artifacts of Mark- ov blanket filtering based on discretized features in small sample size applications 显示文摘Theo A K Marcel J T R Lodewyk F A W 2006Pattern Recognition Letters2006,27,7:1
13The evaporative light scattering detector: some applications in pharmaoeutical analysis显示文摘Marcel K Werner H Philippe C 1997Trends in Analytical Chemistry Amsterdam1997,16,8:1
14Efficacy and side effects of praziquantel against Schistosoma mansoni in a community of western C?te d’Ivoire显示文摘Giovanna Raso Eliézer K N'Goran Abale Toty Anne Luginbühl Cynthia A Adjoua Norbert T Tian-Bi Isaac I Bogoch Penelope Vounatsou Marcel Tanner Jürg Utzinger 2003Transactions of the Royal Society of Tropical Medicine and Hygiene2003,,1:1
15Expression of vascular endothelial growth factors and their receptors during osteoblast differentiation 显示文摘Martine ML Marcel K Chris VDB 2000Endocrinology2000,141,5:1
16In vivo effects of human recombinant TGF-β on bone turnover in normal mice显示文摘Marcellic Yates K Mundy G 1996J Bone Miner Res1996,,5:1
17Do right PLS and do PLS right: A critical review of the application of PLS-SEM in construction management research显示文摘Partial least squares structural equation modeling(PLS-SEM)is a modern multivariate analysis technique with a demonstrated ability to estimate theoretically established cause-effect relationship models.This technique has been increasingly adopted in construction management research over the last two decades.Accordingly,a critical review of studies adopting PLS-SEM appears to be a timely and valuable endeavor.This paper offers a critical review of 139 articles that applied PLS-SEM from 2002 to 2019.Results show that the misuse of PLS-SEM can be avoided.Critical issues related to the application of PLS-SEM,research design,model development,and model evaluation are discussed in detail.This paper is the first to highlight the use and misuse of PLS-SEM in the construction management area and provides recommendations to facilitate the future application of PLS-SEM in this field.Ningshuang ZENG Yan LIU Pan GONG Marcel HERTOGH Markus KÖNIG 2021Frontiers of Engineering Management2021,8,3:1
18J interference on satcom up-links and its suppression显示文摘 FRIEDRICH C 1998International Journal of Satellite Communications1998,,4:1
19Understanding the structure and function of catalases clues from molecular evolution and in vil:ro mutagenesis显示文摘Marcel Z Franz K 1999Progress in bio physics and molecular biology1999,72,:1
20The glass model:A strategy for quantifying global environmental security显示文摘Joseph A Marcel B Frank K 2001Environmental Science & Police2001,4,1:1
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