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57篇 您的检索式:作者名="Mao JS"
    题名 作者 年代 出处 被引量
1Avian influenza virus directly infects human natural killer cells and inhibits cell activity显示文摘Natural killer(NK) cell is a key component of innate immunity and plays an important role in host defense against virus infection by directly destroying infected cells. Influenza is a respiratory disease transmitted in the early phase of virus infection. Evasion of host innate immunity including NK cells is critical for the virus to expand and establish a successful acute infection. Previously,we showed that human influenza H1N1 virus infects NK cells and induces cell apoptosis, as well as inhibits NK cell activity. In this study, we further demonstrated that avian influenza virus also directly targeted NK cells as an immunoevasion strategy. The avian virus infected human NK cells and induced cell apoptosis. In addition, avian influenza virion and HA protein inhibited NK cell cytotoxicity. This novel strategy has obvious advantages for avian influenza virus, allowing the virus sufficient time to expand and subsequent spread before the onset of the specific immune response. Our findings provide an important clue for the immunopathogenesis of avian influenza,and also suggest that direct targeting NK cells may be a common strategy used by both human and avian influenza viruses to evade NK cell immunity.Huawei Mao Yinping Liu Sin Fun Sia JS Malik Peiris Yu-Lung Lau Wenwei Tu 2017Virologica Sinica2017,32,2:4
2Primary study of attenuated live hepatitis A vaccine(H2 strain)in humans显示文摘 Dong DX Zhang HY 1989J Infect Dis1989,159,4:1
3The application of competitive hopfield neural network to medical image segmentation 显示文摘Cheng KS Lin JS Mao CW 1996IEEE Trans Med Imaging1996,15,4:1
4Clonal genetic alterations in the lungs of current and former smokers显示文摘Mao L Lee JS Kurie JM 1997J Natl cancer Inst1997,89,12:1
5Further evaluation of the safety and protective efficacy of live attenuated hepatitis A vaccine (H2-strain) in humans显示文摘Mao JS Chai SA 2007Vaccine2007,15,9:1
6Hepatoma-derived growth factor involved in the carcinogenesis of gastric epithelial cells through promotion of cell proliferation by Erk1/2 activation 显示文摘Mao JS Xu ZF Fang YM 2008Cancer Sci2008,99,11:1
7A preliminary study oil chitosan and gelatin polyelectrolyte complex cytocompatibility by cell cycle and apoptosis analysis显示文摘Mao JS Cui YL 2004Biomaterials2004,25,18:1
8The optimal time-window for surgieal treatment of spontaneous cerebral hemorrhage: Result of prospective randomized eontrolled trial of 500 eases显示文摘Wang YF Wu JS Mao Y 2008Aeta Neuroehir Suppl2008,105,:1
9Structure and properties of bilayer chitosan-gelatin scaffolds 显示文摘Mao JS Zhao LG Yin YJ 2003Biomaterials2003,24,6:1
10A preliminary study on chitosan and gelatin polyelectrolyte complex cytocompatibility by cell cycle and apoptosis analysis显示文摘Mao JS Cui YL Wang XH 2004Biomaterials2004,25,18:1
11Comparison of the antinociceptive effects induced by electroacupuncture and transcutaneous electrical nerve stimulation in the rat 显示文摘Wang J Mao L Han JS 1992Int J Nenrosci1992,65,14:1
12Structure and properties of bilayer chitosan-gelatin scaffolds 显示文摘Mao JS Zhao LG Yin Y J 2003Biomaterials2003,24,6:1
13Frequent microsatellite alterations at chromosomes 9p21 and 3p14 in oral premalignant lesion and their value in cancer risk assessment显示文摘Mao L Lee JS Fan YH 1996Nat Med1996,2,:1
14Structure and properties of bilayer chitosan-gelatin scaffolds 显示文摘Mao JS Zhao LG Yin Y J 2003Biomaterials2003,24,6:1
15A preliminary study on chitosan and gelatin polyelectrolyte complex cytocompatibility by cell cycle and apoptosis analysis显示文摘Mao JS Cui YL Wang XH 2004Biomaterials2004,18,:1
16The role of periaqueductal gray in mediation of analgesia produced by different frequencies electroacupuncture stimulation in rats显示文摘Wang QA Mao LM Han JS 1990Int J Neurosci1990,53,:1
17A preliminary study on chitosan and gelatin polyelectrolyte complex cytocompatibility by cel cycle and apoptosis analysis显示文摘Mao JS Cui YL Wang XH 0,,18:1
18Structure and properties of bilayer chitosan-gelatin scaffolds显示文摘Mao JS Zhao LG Yin YJ 2003Biomaterials2003,24,6:1
19Clinic analysis of 132 iaotrogenic biliary injury 显示文摘WU JS LIAO CH MAO XH 2002Journal of Hepatopancreatobiliary Surgery2002,14,1:1
20Hepatoma-derived growth factor involved in the carcinogenesis of gastric epithelial cells through promotion of cell proliferation by ERK1/2activation显示文摘Mao JS Xu ZF Fang YM 2008Cancer Sci2008,99,11:1
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