|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Chemical composition of Rosmarinus officinalis essential oil and antioxidant action against gastric damage induced by absolute ethanol in the rat显示文摘Objective: To evaluate the antioxidant activity of the essential oil obtained from Rosmarinus officinalis(R. officinalis) in ethanol-induced gastric ulcer model in vivo.Methods: The antioxidant properties of the essential oil obtained from R. officinalis were evaluated against gastric injury induced by absolute ethanol. Gastric tissues were prepared to enzymatic assays. The levels of glutathione, lipid peroxides, and the activities of glutathione peroxidase, superoxide dismutase and myeloperoxidase were measured.Results: Ethanol produced severe hemorrhagic lesions in the stomach with ulcerative lesion of(140.2 ± 37.2) mm2. In animals pretreated with essential oil of R. officinalis(50 mg/kg, p.o.), a significant inhibition of mucosal injury of(21.2 ± 7.1) mm2(84%inhibition) was observed. The essential oil of R. officinalis protected the gastric mucosa probably by modulating the activities of the enzymes(superoxide dismutase and glutathione peroxidase) and increasing or maintaining the levels of glutathione. In addition,lipid peroxides levels were reduced. The essential oil of R. officinalis was analyzed by gas chromatography–mass spectrometer and the main constituents were cineole(28.5%),camphor(27.7%) and alpha-pinene(21.3%).Conclusions: We suggest that the monoterpenes present in the essential oil obtained from R. officinalis may be among the active principles responsible for the antioxidant activity shown by essential oil of R. officinalis. | Christiane Takayama Felipe Meira de-Faria Ana Cristina Alves de Almeida Ricardo Jose Dunder Luis Paulo Manzo Eduardo Augusto Rabelo Socca Leonia Maria Batista Marcos Jose Salvador Alba Regina Monteiro Souza-Brito Anderson Luiz-Ferreira | 2016 | Asian Pacific Journal of Tropical Biomedicine2016，6，8： | 3 |
| 2 | Orthostatic hypotension,an often-neglected problem in community-dwelling older people:discrepancies between studies and real life显示文摘Orthostatic hypotension (OH)is a common condition in older persons.According to the 2011criteria,OH is defined by a sustained reduction of systolic blood pressure of 20 mmHg or a 10mmHg-fall of diastolic blood pressure,[1] Its prevalence increases with age and according to a recent systematic review the pooled prevalence in community dwelling older people is 22.2%.[2]Although OH is largely explained by concurrent clinical conditions (in particular, hypertension,diabetes,malnutrition,vascular encephalopa- thy,anemia,Parkinson's disease)[3],aging per se determines a series of physiological dysfunctions potentially representing its biological substratum (e.g.,reduction in barore- flex-mediated cardiovascular function,altered salt and water balance at renal level,impaired cardiac diastolic filling).It is also noteworthy that age-related changes in pharmacokinetic and pharmacodynamic mechanisms of drugs (especially in the context of polypharmacy)also increase the risk of OH. | Sarah Damanti Dario Consormi Annalisa Valentini Benedetta Cerasoli Martina Biotto Federica Conti Marta Clerici Pasqualina Iannuzzi Emanuela Manzo Paolo D Rossi Simona Ciccone Matteo Cesari | 2018 | Journal of Geriatric Cardiology2018，15，10： | 2 |
| 3 | The role of IL-6 and IL-11 in hyperoxic injury in developing lung显示文摘 | Cao GJ Manzo N | 2008 | Pediatr Pulmonol2008，43，3： | 1 |
| 4 | Histone acetyltransferase inhibitors and preclinical studies显示文摘 | Manzo F Tambaro FP MaiA | 2009 | Expert Opin Ther Pat2009，19，： | 1 |
| 5 | Optical spin-to-orbital angular momentum conversion in inhomogeneous anisntropic media 显示文摘 | Marrucci L Manzo C Paparo D | 2006 | Physical Review Letters2006，96，16： | 1 |
| 6 | Optical spin-to-or- bital angular momentum conversion in inhomogeneous ani- sotropic media显示文摘 | MARRUCCI L MANZO C PAPARO D | 2006 | Physical Review Letters2006，96，16： | 1 |
| 7 | Finding common ground : The importance of place attachment to community participation and planning 显示文摘 | Manzo L C Perkins D D | 2006 | Journal of Plan- ning Literature2006，20，4： | 1 |
| 8 | Production and fungi toxic activity of SCH642305, a secondary metabolite of Penicillium canescens显示文摘 | Nicoletti R Looez-Gresa M P Manzo F_ | 2007 | Mycopathologia2007，163，： | 1 |
| 9 | A Quantitative Assessment of the SBAS Algorithm Performance for Surface Deformation Retrieval from D-InSAR Data显示文摘 | CASU F MANZO M | 2006 | Remote Sensing of Environment2006，102，3： | 1 |
| 10 | Application of the SBAS-DInSAR Technique to Fault Creep:a Case Study of the Haywrd Fault,California显示文摘 | LANARI R CASU F MANZO M | 2007 | Remote Sensing of Environment2007，109，1： | 1 |
| 11 | Modulation of IGF-binding protein-2 and -3 in hyperoxic injury in de- veloping rat lung 显示文摘 | Cherty A Manzo N Waxman AB | 2005 | Pediatr Res2005，58，2： | 1 |
| 12 | Biochemical markers of neurotoxicity:research strategies and epidemiological applications显示文摘 | Costa LG Manzo L | 1995 | Toxicol Lett1995，77，13： | 1 |
| 13 | Inhibition of tumor necrosis factor-alpha and cyclooxigenase-2 by Isatin: A molecular mechanism of protection against TNBS-induced colitis in rats显示文摘 | Eduardo Augusto Rabelo Socca Anderson Luiz-Ferreira Felipe Meira de Faria Ana Cristina de Almeida Ricardo José Dunder Luis Paulo Manzo Alba Regina Monteiro Souza Brito | 2014 | Chemico-Biological Interactions2014，，： | 1 |
| 14 | A quantitative assessment of the SBAS algorithm performance for surface deformation retrieval from DInSAR data 显示文摘 | F Casu M Manzo R Lanari | 2006 | Remote Sensing of Envi- ronment2006，102，： | 1 |
| 15 | Association of CXCL13 and CCL21 expression with the progressive organization of lymphoid-like structures in Sjogren' s syndrome显示文摘 | BaroneF BombardieriM Manzo A | | 0，，： | 1 |
| 16 | DNA damage induced by hyperoxia:Quantitation and correlation with lung injury显示文摘 | Barker GF Manzo ND Cotich KL | 2006 | Am J Respir Cell Mol Biol2006，35，3： | 1 |
| 17 | New diastereomeric bis-sesquiterpenes from Hainan marine sponges Axinyssa wariabilis and Lipastroteth ya ana显示文摘 | Mao S C Manzo E Guo Y W | 2007 | Tetrahedron2007，63，11： | 1 |
| 18 | Mindfulness practice with urban youth:a nursing experience显示文摘 | Manzo J | 2013 | Creat Nurs2013，19，4： | 1 |
| 19 | A fluid dynamic model for supply chains显示文摘 | Ciro D'Apice Rosanna Manzo | 2006 | Networks and Heterogeneous Media2006，1，3： | 1 |
| 20 | Genetic correlations and simultaneous selection for growth and wood density in Pinus patula显示文摘 | Valencia M S Vargas H J Manzo J V | 2001 | Agrociencia2001，35，1： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员