5篇
您的检索式：作者名="Manuel Collado"
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| 1 | Programmed Cell Senescence during Mammalian Embryonic Development显示文摘 | Daniel Mu?oz-Espín Marta Ca?amero Antonio Maraver Gonzalo Gómez-López Julio Contreras Silvia Murillo-Cuesta Alfonso Rodríguez-Baeza Isabel Varela-Nieto Jesús Ruberte Manuel Collado Manuel Serrano | 2013 | Cell2013，，5： | 1 |
| 2 | Cellular Senescence in Cancer and Aging显示文摘 | Manuel Collado Maria A. Blasco Manuel Serrano | 2007 | Cell2007，，2： | 1 |
| 3 | 市场大厦改建——西班牙TERUEL-ZILLA青年活动中心显示文摘1987年,阿拉贡龙(Aragosaurus ischiaticus)骨骼化石被挖掘了出来并被一组来自加尔韦城(Galve)的研究小组(由Sanz、Buscalioni、Cassanovas和Santafe组成)收录在册。这是特鲁埃尔省首只在伊比利亚半岛被发现的恐龙。 | Manuel Collado Nacho Martin Miguel de Guzman Javier de Paz 何文君 | 2012 | 现代装饰2012，，8： | 0 |
| 4 | 西班牙青年活动中心显示文摘Mi5 Arquitectos新近改造完成了西班牙青年活动中心的室内设计,该项目位于西班牙郊外的Fuenlabrada地区,其原址是一栋老旧的市政厅建筑。改造该项目的第一步就是将Fuenlabrada市政厅内原有的装饰元素全部清除.在室内形成视野开阔的活动空间。 | Manuel Collado Nacho Martin Javier de Paz 肖俊 | 2011 | 现代装饰2011，，4： | 0 |
| 5 | Use of a selective enzymatic debridement agent(Nexobrid■)for wound management:Learning curve显示文摘AIM To evaluate the efficacy of Nexobrid~? in the initial management of burns and lessons learned with the procedure.METHODS From January 27^(th) 2015 until January 25^(th) 2016, 25 patients aged between 18-94 years old with deep partial and full thickness burns were treated with Nexobrid~? covering 1%-30% of their total body surface area(TBSA). The debridement was applied in the first 96 h post-injury following the protocol suggested for Nexobrid~?. In patients with burns of more than 15% TBSA a second application of Nexobrid~? was performed. After the removal of the product-4 h post application and after a 2 h period of wet dressing-we used several products to cover the wound like Suprathel~?, Biobrane~?, Mepitel~? with wet dressing, silver sulphadiazine 1% cream, and in some cases even autografts. We treated patients with inhalation injury as well. All the procedures were done under deep sedation, regional blocks in extremities or general anaesthesia in the intensive care unit room or in the operating theatre.RESULTS After these first 25 cases, we have observed that patients with partial thickness burns treated with Nexobrid~?, experienced great benefits in the reduction of the need for autografting compared with the standard of care. This isbecause after selective enzymatic debriding of the burn scar we can distinguish different wound beds, which can coexist in the same patient, and we also managed to associate each one to its ability to epithelize. In major burns, besides the improvement in wound healing, we observed an important improvement in their general state. This may be because SIRS significantly improved through a bloodless debridement of necrotic tissue, decreasing the requirements of vasoactive drugs and fluid resuscitation. Circumferential burns also benefited from enzymatic debridement, observing a decrease in the number of compartment syndromes and the need for escharotomies. At present, we have not observed a positive effect in the evolution and outcome of major burns with inhalation injury.CONCLUSION The introduction of Nexobrid~? shows significant improvement in burn treatment. Cumulative experiences are necessary to adapt its application in all Burns Centres. | Ricardo Palao Jorge Aguilera-Sáez Jordi Serracanta Jose Manuel Collado Bruce Patrik Dos Santos Juan Pedro Barret | 2017 | World Journal of Dermatology2017，6，2： | 0 |
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