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| 1 | Antibacterial Mechanism of Copper-bearing Antibacterial Stainless Steel against E.Coli显示文摘初步的研究通过象 EDTA (ethylenediaminetetraacetic 酸) 那样的微生物学的实验对 E.coli 在忍受铜的抗菌剂不锈钢的抗菌剂机制上被做 complex-ing, DNA 涂和 AFM (原子力量显微镜) 观察。抗菌剂不锈钢在 99.99%.The 抗菌剂率上与抗菌剂率显示出优秀抗菌剂功能到 E.coli,这被测量如果细菌答案是由 EDTA 的 complexed,是弱的,显示铜离子在抗菌剂不锈钢的抗菌剂效果起一个主导的作用。电气泳动实验没显示出在联系抗菌剂不锈钢以后为 E.coli 涂的 DNA 的现象,它意味着 E.coli 的那 DNA 显然没被损坏。E.coli 的形态学在联系抗菌剂不锈钢以后改变了很多,这被 AFM 观察,例如房间墙严重被改变,在房间的大量内容正在被漏。 | Li NAN Weichao YANG Yongqian LIU Hui XU Ying LI Manqi LU Ke YANG | 2008 | Journal of Materials Science & Technology2008，24，2： | 24 |
| 2 | ILF3 is a substrate of SPOP for regulating serine biosynthesis in colorectal cancer显示文摘The Serine-Glycien-One-Carbon(SGOC)pathway is pivotal in multiple anabolic processes.Expression levels of SGOC genes are deregulated under tumoeigenic condltions,suggesting panicipation of oncogenes in deregulating the SGOC biosynthetic pathway.However,the underlying mechanism remains elusive.Here,we identifed that Interleukin enfiarccer-binding factor 3(ILF3)is overexpressed in primary CRC patient specimens and correlates with poor progroosis.ILF3 is critical in regulating the SGOC pathway by directly regulating the mRNA stability of SGOC genes,thereby increasing SGOC genes expression and facilitating tumor growth.Mehhanktic studies showed that the EGF-MIEK-ERK pathway nnediates ILF3 phosphorylation,which hin ders E3 ligase speckle-type POZ protein(SPOP)-mediated poly-ubiquitination and degradation of ILF3.Sign iftca ntly,combination of SGOC inhibitor and the anti-EGFR monoclonal antibody cetuximab can hinder the growth of patient-derived xenografts that sustain high ERK-ILF3 levels.Taken together,deregutation of ILF3 via the EGF-ERK signaling plays an important role in systemic serine metabolic reprogramming and confers a predilection toward CRC development.Our findings indicate that clinical evaluation of SCOC inhibitor is warranted for CRC patients with ILF3 overexpression. | Kai Li Jian-lin Wu Baifu Qin Zongmin Fan Qin Tang Weisi Lu Haipeng Zhang Fan Xing Manqi Meng Shaomin Zou Wenxia Wei Honglei Chen Jian Cai Huaiming Wang Hui Zhang Jiayue Cai Ling Fang Xiqing Bian Chuangqi Chen Ping Lan Bart Ghesquiere Lekun Fang Mong-Hong Lee | 2020 | Cell Research2020，30，2： | 6 |
| 3 | Mg AmorphousZr_(0.9)Ti_(0.1)(Ni_(0.57)Mn_(0.28)V_(0.1)Co_(0.05))_(2.1)Composite for Hydrogen Storage显示文摘The reactive mechanical alloying (RMA) method was used to produce Mg-40 wt pct amorphous Zr0.9Ti0.1(Ni0.57-Mn0.25V0.1Co0.05)2.1 composite in this study, and the absorption/desorption property of the composite was improved remarkably. The composite possessed excellent kinetic properties even at moderate temperature (393 K) without activation. Owing to the formation of the embrittle MgH2, the reactive mechanical milling process reduced the particle size of Mg and made the composite phase being highly efficiently distributed, which determined the excellent hydriding properties of the composite. | Haiyan LENG, Demin CHEN, Manqi LU, Haifeng ZHANG, Huiming CHENG and Ke YANGInstitute of Metal Research, Chinese Academy of Sciences, Shenyang 110016, China | 2003 | Journal of Materials Science & Technology2003，19，2： | 2 |
| 4 | Development of a metal hydride refrigeration system as an exhaust gas-driven automobile air conditioner显示文摘 | Feng Qin Jiangping Chen Manqi Lu Zhiiu Chen Yimin Zhou Ke Yang | 2007 | Renewable Energy2007，32，： | 1 |
| 5 | Improvement of Hydrogen Storage Properties of La0.6M0.4Ni4.8Mn0.2 Alloys显示文摘Investigation has been carried out to find the effects of Nd substitution and Cu addition on the hydrogen storage properties of AB5-type alloy with a multicomponent La0.6M0.4Ni4.8Mn0.2 (M=Y, Nd) system. La0.6Y0.4Ni4.8Mn0.2,which was used in an air-conditioning system, showed poor hysteresis and sloping characteristics, which led to a decrease concerning the coefficient of performance of the system. By the substitution of Nd for Y, the hydrogenstorage capacity increased, and the plateau pressure decreased a little, but the hydrogen absorption kinetics decreased dramatically. Cu addition can effectively improve the kinetics of hydride formation without changing the hydrogen storage capacity of La0.6Nd0.4Ni4.8Mn0.2. It has been found that La0.6Nd0.4Ni4.8Mn0.2Cu0.1 alloy showed good hydrogen storage characteristics for metal hydride air-conditioning system. The results showed that, for each component of La0.6Mo.4Ni4.8Mn0.2, the effective hydrogen storage capacity increased with decrease of the unit cell parameter c/a and the hydrogen absorption plateau pressure increased with decrease of the parameter a. | Ping DU, Wei CAO, Manqi LU, Jiangping CHEN and Ke YANGInstitute of Metal Research, Chinese Academy of Sciences, Shenyang 110016, China | 2004 | Journal of Materials Science & Technology2004，20，4： | 0 |
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