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| 1 | 脑外伤后认知障碍社区康复的可行性研究显示文摘目的:了解认知康复服务的需求,有关专业人士的认知康复知识水平以及他们对创新性认知康复的态度和接受程度,以便帮助制定认知障碍社区康复计划。方法:采用自行设计的结构式问卷调查表,155名神经外科医生、康复科医生、康复治疗师、护士等接受了问卷调查。结果:95.4%的调查对象认为在中国有必要开展脑外伤后的认知障碍康复。按康复的重要性需要优先考虑的前4个问题为∶语言能力、记忆力、定向力、注意力;脑外伤后康复场所的重要性依次为∶家庭、医院、社区;三种康复训练方法的重要性依次为∶面对面方式、电脑辅助方式、网上远程指导方式。家庭是首选的康复场所、“面对面”是主要康复方式。康复训练方式与康复场所之间存在良好的相关关系,即相对于其他训练方式,在家庭或医院人们更愿意选择“面对面”训练;对于远程指导而言,在家中则比医院能更好地发挥作用。结论:①认知康复服务正在快速发展并获得有关专业人士的大力支持;②“面对面”训练仍是认知康复主要服务方式;③在家中开展认知康复远程指导也是一项合适的服务选择,以家庭为基础的康复是社区康复的重要内容,网上和/或远程指导的认知康复服务值得大力提倡;④需进一步探讨创新性认知康复服务方式的有效性和实用性。 | 窦祖林 Man DWK 朱洪翔 欧海宁 TamS F Hui-Chan CWY | 2003 | 中国康复医学杂志2003，18，5： | 12 |
| 2 | Blood glucose changes surrounding initiation of tumor-necrosis factor inhibitors and conventional disease-modifying anti-rheumatic drugs in veterans with rheumatoid arthritis显示文摘AIM To determine the scope of acute hypoglycemic effects for certain anti-rheumatic medications in a large retrospective observational study. METHODS Patients enrolled in the Veterans Affairs Rheumatoid Arthritis (VARA) registry were selected who, during follow-up, initiated treatment with tumor necrosis factor inhibitors (TNFi's, including etanercept, adalimumab, infliximab, golimumab, or certolizumab), prednisone, or conventional disease-modifying anti-rheumatic drugs(DMARDs), and for whom proximate random blood glucose (RBG) measurements were available within a window 2-wk prior to, and 6 mo following, medication initiation. Similar data were obtained for patients with proximate values available for glycosylated hemoglobin A1C values within a window 2 mo preceding, and 12 mo following, medication initiation. RBG and A1C measurements were compared before and after initiation events using paired t-tests, and multivariate regression analysis was performed including established comorbidities and demographics.RESULTS Two thousands one hundred and eleven patients contributed at least one proximate measurement surrounding the initiation of any examined medication. A significant decrease in RBG was noted surrounding 653 individual hydroxychloroquine-initiation events(-3.68 mg/dL, P = 0.04), while an increase was noted for RBG surrounding 665 prednisone-initiation events(+5.85 mg/d L, P < 0.01). A statistically significant decrease in A1C was noted for sulfasalazine initiation, as measured by 49 individual initiation events(-0.70%, P < 0.01). Multivariate regression analyses, using methotrexate as the referent, suggest sulfasalazine (β =-0.58, P = 0.01) and hydroxychloroquine(β =-5.78, P = 0.01) use as predictors of lower post-medicationinitiation RBG and A1C values, respectively. Analysis by drug class suggested prednisone (or glucocorticoids) as predictive of higher medication-initiation event RBG among all start events as compared to DMARDs, while this analysis did not show any drug class-level effect for TNFi. A diagnosis of congestive heart failure(β = 4.69, P = 0.03) was predictive for higher post-initiation RBG values among all medication-initiation events.CONCLUSION No statistically significant hypoglycemic effects surrounding TNFi initiation were observed in this large cohort. Sulfasalazine and hydroxychloroquine may have epidemiologically significant acute hypoglycemic effects. | Patrick R Wood Evan Manning Joshua F Baker Bryant England Lisa Davis Grant W Cannon Ted R Mikuls Liron Caplan | 2018 | World Journal of Diabetes2018，9，2： | 8 |
| 3 | Uteroglobin基因G38A多态性与IgA肾病相关关系显示文摘【目的】 研究Uteroglobin 基因G38A多态性与我国IgA肾病的相关关系? 【方法】 用PCR-RFLP法和PCR产物直接测序法鉴定基因型,采用以家庭为基础的传递不平衡检验(transmission disequilibrium test ,TDT)?单倍体相对风险(haplotype-based haplotype relative risk, HRR)分析,以及病例-对照研究分析Uteroglobin 基因G38A多态性与我国IgA肾病的相关关系?【结果】 ① GG基因型在IgA肾病伴高血压组与肾功能进展组中的分布频率显著高于AA +GA(P=0.042,χ2=4.117;P=0.039,χ2=4.240)(病例组362例?正常对照组201例);② 135个满足TDT分析的核心家庭中,杂合子父母传递给患病子代的等位基因频率不比预期值高(χ2=0.457, P=0.499);③ HRR分析显示此多态性不使患者具有更高的发病风险(χ2=0.520, P=0.471, HRR=0.878)?【结论】 Uteroglobin GG基因型可能和IgA肾病的进展及高血压相关,但和IgA肾病的易感性不相关? | 杜勇 李幼姬 李彩霞 郭辉 Joseph CK Leung Man F Lam 杨念生 黄锋先 方积乾 Patrick H Maxwell 黎嘉能 王一鸣 | 2004 | 中山大学学报(医学科学版)2004，25，3： | 4 |
| 4 | 胰岛素抵抗者的葡萄糖刺激胰岛素分泌的增强作用受损显示文摘T2DM根据IR和胰岛p细胞功能障碍进行分类,后者可能是胰岛B细胞胰岛素信号缺陷引起的。为评估IR人群较之胰岛素敏感人群在胰岛素调节葡萄糖刺激的胰岛素分泌(GSIS)方面的作用,美国研究者对10例IGT患者. | Halperin F Lopez X Manning R | 2014 | 中国糖尿病杂志2014，22，1： | 4 |
| 5 | Laser transformation hardening of AISI440C martensitic stainless steel for higher cavitation erosion resistance显示文摘 | Lo K H Cheng F T Man H C | 2003 | Surface and Coating Technology2003，173，： | 2 |
| 6 | Hydrogen effect on the cavitation erosion resistance of AISI 316L stainless steel laser surface modified with NiTi显示文摘 | Chiu K Y C F T Man H C | 2007 | Materials Letters2007，61，1： | 1 |
| 7 | Experimental colonic phantom for the evaluatlon of the optimal scanning technique for CT colonography using a multidetector spiral CT equipntent显示文摘 | Laghi A lan naccone R Man giapane F | 2003 | Eur Radiol2003，13，3： | 1 |
| 8 | Fungal biotransformation of mosapride by Cunninghamella elegans 显示文摘 | Sun XH Man F Pang LY | 2009 | Journal of Molecular Catalysis B : Enzymatic2009，，1： | 1 |
| 9 | Characteristics, apa tire-forming ability and corrosion resistance of NiTi surface modified by AC anodization 显示文摘 | WONG M H CHENG F T MAN H C | 2007 | Appl Surface Sci2007，253，18： | 1 |
| 10 | Assessment of De- sign Formulas for In-Plane FRP Strengthening of Masonry Walls显示文摘 | Prota A Man{redi G Nardone F | 2008 | Journal of Composites for Con- struction2008，12，6： | 1 |
| 11 | Expression of bovine trypsin in Lactococcus lactis显示文摘 | Yao L Man C Zhao F | 2010 | Int Dairy J2010，20，11： | 1 |
| 12 | The effect test method and surface condition on pitting potential of single and duplex phase 304 L stainless steel 显示文摘 | Manning P E Duquette D Jand Savage W F | 1979 | Corroion1979，35，4： | 1 |
| 13 | The competitiveness of small and medium enterprises:a conceptualization with foeus on entrepreneurial competencies 显示文摘 | MAN T W Y LAU T CHAN K F | 2002 | Journal of Business Venturing2002，17，： | 1 |
| 14 | An introduction to contingent (closed-loop) brain electrical stimulation for sei- zure blockage, to ultra-short-term clinical trials, and to multi dimensional statistical analysis of therapeutic efficacy 显示文摘 | OSORIO I FREI M G MANLY B F | 2001 | J Clin Neurophysiol2001，18，6： | 1 |
| 15 | Efficient algo- rithms for generalized stable marriage and roomates prob- lems 显示文摘 | FLEINER T IRVING R W MAN L D F | 2007 | Theoretical Computer Science2007，381，13： | 1 |
| 16 | Sulfur bearing capacity of hydrogen sulfide gas 显示文摘 | Swiit S C Manning F C Thompson R E | 1976 | SPEJ1976，4，16： | 1 |
| 17 | The pyrolysis kinetics of bagasse at low heating rates显示文摘 | A Man S Stub Ington J F | 1993 | Biomass Bioenergy1993，5，2： | 1 |
| 18 | NF-κB is activated during acute inflammation in vivo in association with molecule gene expression and leukocyte recruitment显示文摘 | BELL F P ROSENBLOOM J G | 1995 | J Inflamm1995，45，4： | 1 |
| 19 | Is en-dogenous glycerol a determinant of stratum corneum hydration in humans?显示文摘 | Choi EH Man MQ Wang F | 2005 | J In-vest Dermatol2005，125，2： | 1 |
| 20 | Allelic imbalances in endometrial stromal neoplasms: frequent genetic alterations in the nontumorous nomral-appearing endometrial and myometrial tissues 显示文摘 | Moinfar F Kremser M L Man Y G | 2004 | Gynecol Oncol2004，95，3： | 1 |
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