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| 1 | Randomised controlled trial comparing modified Sano's and narrow band imaging international colorectal endoscopic classifications for colorectal lesions显示文摘AIM To assess the utility of modified Sano′s(MS) vs thenarrow band imaging international colorectal endoscopic(NICE) classification in differentiating colorectal polyps.METHODS Patients undergoing colonoscopy between 2013 and 2015 were enrolled in this trial.Based on the MS or the NICE classifications,patients were randomised for real-time endoscopic diagnosis.This was followed by biopsies,endoscopic or surgical resection.The endoscopic diagnosis was then compared to the final(blinded) histopathology.The primary endpoint was the sensitivity(Sn),specificity(Sp),positive predictive value(PPV) and negative predictive value(NPV) of differentiating neoplastic and non-neoplastic polyps(MSⅡ/Ⅱo/Ⅲa/Ⅲb vs I or NICE 1 vs 2/3).The secondary endpoints were 'endoscopic resectability'(MSⅡ/Ⅱo/Ⅲa vs Ⅰ/Ⅲb or NICE 2 vs 1/3),NPV for diminutive distal adenomas and prediction of post-polypectomy surveillance intervals.RESULTS A total of 348 patients were evaluated.The Sn,Sp,PPV and NPV in differentiating neoplastic polyps from non-neoplastic polyps were,98.9%,85.7%,98.2% and 90.9% for MS;and 99.1%,57.7%,95.4% and 88.2% for NICE,respectively.The area under the receiver operating characteristic curve(AUC) for MS was 0.92(95%CI:0.86-0.98);and AUC for NICE was 0.78(95%CI:0.69,0.88).The Sn,Sp,PPV and NPV in predicting 'endoscopic resectability' were 98.9%,86.1%,97.8% and 92.5% for MS;and 98.6%,66.7%,94.7% and 88.9% for NICE,respectively.The AUC for MS was 0.92(95%CI:0.87-0.98);and the AUC for NICE was 0.83(95%CI:0.75-0.90).The AUC values were statistically different for both comparisons(P = 0.0165 and P = 0.0420,respectively).The accuracy for diagnosis of sessile serrated adenoma/polyp(SSA/P) with high confidence utilizing MS classification was 93.2%.The differentiation of SSA/P from other lesions achieved Sp,Sn,PPV and NPV of 87.2%,91.5%,89.6% and 98.6%,respectively.The NPV for predicting adenomas in diminutive rectosigmoid polyps(n = 150) was 96.6% and 95% with MS and NICE respectively.The calculated accuracy of post-polypectomy surveillance for MS group was 98.2%(167 out of 170) and for NICE group was 92.1%(139 out of 151).CONCLUSION The MS classification outperformed the NICE classification in differentiating neoplastic polyps and predicting endoscopic resectability.Both classifications met ASGE PIVI thresholds. | Leonardo Zorrón Cheng Tao Pu Kuan Loong Cheong Doreen Siew Ching Koay Sze Pheh Yeap Amanda Ovenden Mahima Raju Andrew Ruszkiewicz Philip W Chiu James Y Lau Rajvinder Singh | 2018 | World Journal of Gastrointestinal Endoscopy2018，10，9： | 4 |
| 2 | Bioactive compounds and probiotics-a ray of hope in COVID-19 management显示文摘The use of bioactive compounds and probiotic bacteria against the viral diseases in human is known for a long time.Anti-viral,anti-inflammatory and anti-allergic properties of bioactive compounds and bacteria with probiotic properties in respiratory viral diseases may have significance to enhance immunity.This review highlights some of the important bioactive compounds and probiotic bacteria,suggesting them as a ray of hope in the milieu of the COVID-19 management. | Indu Bhushan Mahima Sharma Malvika Mehta Shivi Badyal Varun Sharma Indu Sharma Hemender Singh Srinivas Sistla | 2021 | Food Science and Human Wellness2021，10，2： | 3 |
| 3 | Enzymatic properties of the ferredoxin-dependent nitrite reductase from Chlamydomonas reinhardtii. Evidence for hydroxylamine as a late intermediate in ammonia production显示文摘 | Masakazu Hirasawa Jatindra N. Tripathy Frederik Sommer Ramasamy Somasundaram Jung-Sung Chung Matthew Nestander Mahima Kruthiventi Masoud Zabet-Moghaddam Michael K. Johnson Sabeeha S. Merchant James P. Allen David B. Knaff | 2010 | Photosynthesis Research2010，，2： | 1 |
| 4 | Crossover of Organizational Commitment显示文摘 | RebeccaA. Bull Schaefer StephenG. Green Mahima Saxena HowardM. Weiss ShelleyM. MacDermid Wadsworth | 2013 | Human Performance2013，，4： | 1 |
| 5 | 2-Iminohomopiperdinium salts as selective inhibitors of iNOS 显示文摘 | Donald WJ Karen BP Mahima T | 1998 | J Med Chem1998，41，： | 1 |
| 6 | Klestadt ' s cyst : a rarity显示文摘 | Patil K Mahima VG Divya A | 2007 | Indian J Dent Res2007，18，： | 1 |
| 7 | Localization of impacted permanent maxillary canine using single panoramic radiograph 显示文摘 | Sudhakar S Patil K Mahima V G | 2009 | IndianJ Dent Res2009，20，3： | 1 |
| 8 | Evaluation of in vivo genotoxicity of cypermethrin in Drosophila melanogaster using the alkaline Comet assay显示文摘 | Indranil Mukhopadhyay D Kar Chowdhuri Mahima Bajpayee | 2004 | Mutagenesis2004，19，2： | 1 |
| 9 | Light-induced modulation of self-assembly on spiropyran-capped gold nanoparticles:a potential system for the controlled release of amino acid derivatives显示文摘 | Ipe B I Mahima S Thomas K G | 2003 | Journal of the American Chemical Society2003，125，24： | 1 |
| 10 | Android based mobile application development and it's security 显示文摘 | SUHAS H MAHIMA M K | 2012 | International Journal of Computer Trends and Technology2012，3，3： | 1 |
| 11 | Tuning the aspect ratio of silver nanostructures:the effect of solvent mole fraction and 4-aminothiophenol concentration显示文摘 | Jadab Sharma Nirmalya K Chaki Subhramannia Mahima | 2004 | Journal of Materials Chemistry2004，14，6： | 1 |
| 12 | Oral histoplasmo- sis显示文摘 | Patil K Mahima VG Prathibha Rani RM | 2009 | J Indian Soc Periodontol2009，13，： | 1 |
| 13 | Facial plexifonn neurofibrema in a child with neurofibrematosis type I:a case repert显示文摘 | Patil K Mahima VG Shetty SK | 2007 | J Indian Soc Pedod Prey Dent2007，25，1： | 1 |
| 14 | Prevalence of zygomatic air cell defect in adults-A retrospective panoramic radiographic analysis 显示文摘 | KARTHIKEYA PATIL MAHIMA V G SUCHETHA V G N | 2012 | Eur J Radiol2012，81，6： | 1 |
| 15 | Branched titania nanotubes through anodization voltage control显示文摘 | Gorun Butail P.G. Ganesan R. Teki R. Mahima N. Ravishankar D.J. Duquette Ganpati Ramanath | 2011 | Thin Solid Films2011，，： | 1 |
| 16 | Surface plasmon resonance based fiber-optic sensor with double resonance dips显示文摘 | Navneet K Sharma Mahima Rani Vivek Sajal | 2013 | Sensors and Actuators B2013，188，： | 1 |
| 17 | Synthesis of platinum Y-junction nanostru-ctures using hierarchically designed alumina templates and their enhanced electrocatalytic activity for fuel-cell applications显示文摘 | Mahima S Kannan R Komath I | 2008 | Chem Mater2008，20，： | 1 |
| 18 | Solvent-assisted one-pot synthesis and self-assembly of 4-aminothiophenol-capped gold nano-particles显示文摘 | Sharma J Mahima S Kakade B A Pasrieha R Mandale A B:Vijayamohanan K | 2004 | The Journal of Physical Chemistry B2004，108，13： | 1 |
| 19 | Contamination of water sources in mysore city by pesticide residues and plasticizer - a cause of health concern 显示文摘 | Kanchana Mysore Somashekar Mahima M R Manjunath K C | 2015 | A- quatic Procedia2015，4，： | 1 |
| 20 | Inorganic versus organic selenium supplementation: a review 显示文摘 | MAHIMA VERMA A K KUMAR A | 2012 | Pak J Biol Sci2012，15，9： | 1 |
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