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| 1 | Characterization of functional biliary pain and dyspeptic symptoms in patients with sphincter of Oddi dysfunction:Effect of papillotomy显示文摘AIM: To characterize functional biliary pain and other gastrointestinal (GI) symptoms in postcholecystectomy syndrome (PCS) patients with and without sphincter of Oddi dysfunction (SOD) proved by endoscopic sphincter of Oddi manometry (ESOM), and to assess the post- endoscopic sphincterotomy (EST) outcome. METHODS: We prospectively investigated 85 cholecystectomized patients referred for ERCP because of PCS and suspected SOD. On admission, all patients completed our questionnaire. Physical examination, laboratory tests, abdominal ultrasound, quantitative hepatobiliary scintigraphy (QHBS), and ERCP were performed in all patients. Based on clinical and ERCP findings 15 patients had unexpected bile duct stone disease and 15 patients had SOD biliary typeⅠ. ESOM demonstrated an elevated basal pressure in 25 patients with SOD biliary-type Ⅲ. In the remaining 30 cholecystectomized patients without SOD, the liver function tests, ERCP, QHBS and ESOM were all normal. As a control group, 30 ‘asymptomatic’ cholecystectomized volunteers (attended to our hospital for general cardiovascular screening) completed our questionnaire, which is consisted of 50 separate questions on GI symptoms and abdominal pain characteristics. Severity of the abdominal pain (frequency and intensity) was assessed with a visual analogue scale (VAS). In 40 of 80 patients having definite SOD (i.e. patients with SOD biliary typeⅠand those with elevated SO basal pressure on ESOM), an EST was performed just after ERCP. In these patients repeated questionnaires were filled at each follow-up visit (at 3 and 6 mo) and a second lookQHBS was performed 3 mo after the EST to assess the functional response to EST. RESULTS: The analysis of characteristics of the abdominal pain demonstrated that patients with common bile duct stone and definite SOD had a significantly higher score of symptomatic agreement with previously determined biliary-like pain features than patient groups of PCS without SOD and controls. In contrary, no significant differences were found when the pain severity scores were compared in different groups of PCS patients. In patients with definite SOD, EST induced a significant acceleration of the transpapillary bile flow; and based on the comparison of VASs obtained from the pre- and post-EST questionnaires, the severity scores of abdominal pain were significantly improved, however, only 15 of 35 (43%) patients became completely pain free. Post-EST severity of abdominal pain by VASs was significantly higher in patients with predominant dyspepsia at initial presentation as compared to those without dyspeptic symptoms. CONCLUSION: Persistent GI symptoms and general patient dissatisfaction is a rather common finding after EST in patients with SOD, and correlated with the presence of predominant dyspeptic symptoms at the initial presentation, but does not depend on the technical and functional success of EST. | László Madácsy Roland Fejes Gábor Kurucsai Ildikó Joó András Székely Viktória Bertalan Attila Szepes János Lonovics | 2006 | World Journal of Gastroenterology2006，12，42： | 33 |
| 2 | Prophylactic pancreas stenting followed by needle-knife fistulotomy in patients with sphincter of Oddi dysfunction and difficult cannulation:new method to prevent post-ERCP pancreatitis显示文摘 | MADáCSY L KURUCSAI G FEJES R | 2009 | Dig Endosc2009，21，1： | 1 |
| 3 | Effect of cellulases, solvent type and particle size distribution on the extraction of chlorogenic acid and other phenols from spent coffee grounds显示文摘 | Manuel P Abigaille G T Mads P | 2007 | American Journal of Food Technology2007，2，7： | 1 |
| 4 | Perinatal systemic in-flammatory response syndrome and retinopathy of prematurity 显示文摘 | SOOD B G MAD AN A SAHA S | 2010 | Pediatr Res2010，67，4： | 1 |
| 5 | Control of citrus postharvest green and blue mold and sour rot by tea saponin combined with imazalil and prochloraz显示文摘 | HAO W N ZHONG G H HU M Y LUO J J WENG Q F MUHAM MAD R | 2010 | Postharvest Biology and Technology2010，56，： | 1 |
| 6 | On the theory of systematic sampling显示文摘 | MADOW W G MAD OW L G | 1944 | Annals of Mathematical Statistics1944，，15： | 1 |
| 7 | Identification of antiangiogenic and anti-inflammatory proteins in human amniotic membrane显示文摘 | HAO Y MAD H HWANG D G | 2000 | Cornea2000，19，： | 1 |
| 8 | Effect of du- ration of passive stretch on hip abduction range of motion显示文摘 | MADDING S W WONG J G HALLUM A | 1987 | J Orthop Sport Phys1987，8，40： | 1 |
| 9 | Cognitive impairment in chronic heroin addicts显示文摘 | A mad S Ahmad H Bindra G | 1989 | J Pers Clin Stud1989，5，： | 1 |
| 10 | Strategic investment in climate friendly technologies: The impact of global emissions trading显示文摘 | Mads G Cathrine H | 2014 | Environment Resource Economy2014，59，： | 1 |
| 11 | Evaluation of simplified ventilation system with direct air supply through the facade in a school in a cold climate显示文摘 | Mads Mysen Peter G Schild Vidar Hellstrand | 2005 | Energy and Buildings2005，37，2： | 1 |
| 12 | High efficiency tandem organic light-emitting devices with A1/WO3/Au interconnecting layer显示文摘 | ZHANG H M DAI Y F MAD G | 2007 | Applied Physics Letters2007，91，12： | 1 |
| 13 | Cladribine MR/ Study Group 显示文摘 | Rice G P Filippi M Comi (2 Cladribine and progressive MS: clinical mad MR/outcomes of a multicenter controlled trial | 2000 | Neurology2000，54，5： | 1 |
| 14 | Synthesis and X-ray crystal structure of a 2,4,5-trisubstituted 1,2,4-triazolin-3-one显示文摘 | Madding G Smith W Sheldon R | 1985 | J Heterocycl Chem1985，22，4： | 1 |
| 15 | Osteoinductionin umbilical cord - and palate periosteum - derived mesenchymalstem cells显示文摘 | CABALLERO M REED C R MAD AN G | 2010 | Ann Plast Surg2010，64，5： | 1 |
| 16 | Prophylactic pan-creas stenting followed by needle - knife fistulotomy in patients withsphincter of oddi dysfunction and difficult cannulation: new methodto prevent post - ERCP pancreatitis显示文摘 | MADCSY L KURUCSAI G FEJES R | 2009 | Dig Endosc2009，21，21： | 1 |
| 17 | A storage protein-like trypsin inhibitor from the Moth bean (Phaseolus acutifolius) with antiproliferative activity toward lymphoma cells显示文摘 | MAD Z SUN J ZHANG G Q | 2010 | Protein Pept Lett2010，17，6： | 1 |
| 18 | Characterization and three-dimensional structures of two dis?tinct bacterial xyloglucanases from families GH5 and GH12显示文摘 | TRACEY M G FARID M I KATHERINE M JENS M E SHIRLEY R JOHAN P T MADS E B PER L J STEFFEN D KATJA S J TORBEN V B KEITH S W HARRY B GIDEON J D | 2007 | Journal of Biological Chemistry2007，282，19： | 1 |
| 19 | Enhancement of light extraction of green top-emitting organic light-emitting diodes with refractive index gradually changed coupling layers 显示文摘 | FAN Y CHEN J S MAD G | 2013 | Organic Electron- ics2013，14，12： | 1 |
| 20 | Improved survival with early adjuvant chemotherapy after colonic resection for stage III colonic cancer: A nationwide study显示文摘 | Mads Klein Najah Azaquoun Benny Vittrup Jensen Ismail G?genur | 2015 | J. Surg. Oncol2015，，5： | 1 |
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