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| 1 | The performance of tests of publication bias and other sample size effects in systematic reviews of diagnostic test accuracy was assessed显示文摘 | Jonathan J. Deeks Petra Macaskill Les Irwig | 2005 | Journal of Clinical Epidemiology2005,,9: | 2 |
| 2 | The Association of Surgical Margins and Local Recurrence in Women with Early-Stage Invasive Breast Cancer Treated with Breast-Conserving Therapy: A Meta-Analysis显示文摘 | Nehmat Houssami Petra Macaskill M. Luke Marinovich Monica Morrow | 2014 | Annals of Surgical Oncology2014,,3: | 2 |
| 3 | Reduced striatal volumes in Parkinson’s disease:a magnetic resonance imaging study显示文摘Background:The presence and extent of structural changes in the brain as a consequence of Parkinson’s disease(PD)is still poorly understood.Methods:High-resolution 3-tesla T1-weighted structural magnetic resonance images in sixty-five PD and 27 age-matched healthy control participants were examined.Putamen,caudate,and intracranial volumes were manually traced in the axial plane of 3D reconstructed images.Striatal nuclei volumes were normalized to intracranial volume for statistical comparison.Disease status was assessed using the Unified Parkinson’s Disease Rating Scale and Hoehn and Yahr scale.Cognitive status was assessed using global status tests and detailed neuropsychological testing.Results:Both caudate and putamen volumes were smaller in PD brains compared to controls after adjusting for age and gender.Caudate volumes were reduced by 11%(p=0.001)and putamen volumes by 8.1%(p=0.025).PD striatal volumes were not found to be significantly correlated with cognitive or motor decline.Conclusion:Small,but significant reductions in the volume of both the caudate and putamen occur in PD brains.These reductions are independent of the effects of age and gender,however the relation of these reductions to the functional loss of dopamine,which is characteristic of PD,remains unclear. | Toni L Pitcher Tracy R Melzer Michael R MacAskill Charlotte F Graham Leslie Livingston Ross J Keenan Richard Watts John C Dalrymple-Alford Tim J Anderson | 2012 | Translational Neurodegeneration2012,1,1: | 2 |
| 4 | Caregiver burden is increased in Parkinson’s disease with mild cognitive impairment (PD-MCI)显示文摘Background:There is limited evidence on caregiver outcomes associated with mild cognitive impairment in patients with Parkinson’s disease(PD-MCI)and the coping strategies used by these caregivers.Methods:To investigate this relationship,we examined levels of burden,depression,anxiety,coping strategies and positive aspects of caregiving in the informal caregivers of 96 PD patients.The PD patients were classified using MDS-Task Force Level II criteria as showing either normal cognition(PD-N;n=51),PD-MCI(n=30)or with dementia(PDD;n=15).Results:Mean Zarit Burden Interview(ZBI)score increased significantly between carers of PD-N(M=13.39,SD=12.22)compared to those of PD-MCI patients(M=22.00,SD=10.8),and between carers of PD-MCI and PDD patients(M=29.33,SD=9.59).Moreover,the proportion of carers showing clinically significant levels of burden(ZBI score≥21)also increased as the patients’cognitive status declined(18% for PD-N;60% for PD-MCI;and 80%for PDD)and was mirrored by an increasing amount of time spent providing care by the caregivers.Caregiver ZBI score was independent of patient neuropsychiatric symptoms,motor function,disease duration and time that caregivers spent caregiving.Caregiver use of different coping strategies increased with worsening cognition.However,we found only equivocal evidence that the use of problem-focused,emotion-focused and dysfunctional coping mediated the association between patient cognitive status and caregiver burden,because the inverse models that used caregiver burden as the mediator were also significant.Conclusions:The study highlights the impact of Parkinson’s disease on those providing care when the patient’s cognition is poor,including those with MCI.Caregiver well-being has important implications for caregiver support,nursing home placement and disease course. | Ann J.Jones Roeline G.Kuijer Leslie Livingston Daniel Myall Kyla Horne Michael MacAskill Toni Pitcher Paul T.Barrett Tim J.Anderson John C.Dalrymple-Alford | 2017 | Translational Neurodegeneration2017,6,1: | 2 |
| 5 | Accuracy and 8urgical impact of magnetic resooance imaging in breast cancer staging:Systematic review and meta-analysis in detection of multifocal and multicentric cancer显示文摘 | Houssami N CiaRo S Macaskill P | 2008 | J Clin Oncol2008,26,19: | 1 |
| 6 | Meta-analysis of Pap test accuracy 显示文摘 | Fahey MT Irwig L Macaskill P | 1995 | Am J Epidemiol1995,141,7: | 1 |
| 7 | MRI findings are more common in selected patients with acute low back pain than controls显示文摘 | Hancock M Maher C Macaskil P | | 0,,02: | 1 |
| 8 | Meta- analysis ofthe impact of surgical margins on local recurrence in womenwithearly- stage invasive breast cancer treated with breast- conservingtherapy显示文摘 | Houssami N Macaskill P Marinovich ML | 2010 | Eur J Cancer2010,46,18: | 1 |
| 9 | Meta-analytic methods for diagnostic test accuracy显示文摘 | Irwig L Macaskill P Glasziou P | 1995 | J Clin Epidemiol1995,48,: | 1 |
| 10 | Serum levels of phosphorus, parathyroid hormone, and calcium and risks of death and cardiovascular disease in individuals with chronic kidney disease: a systematic review and meta- analysis显示文摘 | Palmer SC Hayen A Macaskill P | 2011 | JAMA2011,305,11: | 1 |
| 11 | Technical aspects of breast MRI—do they affect outcomes?显示文摘 | Ruth Warren Stefano Ciatto Petra Macaskill Richard Black Nehmat Houssami | 2009 | European Radiology2009,,7: | 1 |
| 12 | The Mo CA:well-suited screen for cognitive impairment in Parkinson disease显示文摘 | Dalrymple-Alford JC Macaskill MR Nakas CT | 2010 | Neurology2010,75,19: | 1 |
| 13 | The performance of tests of publication bias and other sample size effects in sys- tematic reviews of diagnostic test accuracy was assessed 显示文摘 | Deeks JJ Macaskill P Irwig L | 2005 | J Clin Epidemiol2005,58,9: | 1 |
| 14 | Meta-analysis:retinal vessel caliber and risk for coronary heart disease显示文摘 | Mc Geechan K Liew G Macaskill P | 2009 | Ann Intern Med2009,151,6: | 1 |
| 15 | Meta-ana- lysis: vitamin D compounds in chronic kidney disease显示文摘 | Palmer SC McGregor DO Macaskill P | 2007 | Ann Intern Med2007,147,12: | 1 |
| 16 | Meta-analytic methods for diagnostic test accuracy显示文摘 | Irwig L Macaskill P Glasziou P Fahey M | 1995 | J Clin Epidemiol1995,48,: | 1 |
| 17 | 显示文摘 | Sankar M Macaskill J B Bates R G J Solution Chem | 1979 | 8:887-8951979,8,: | 1 |
| 18 | Serum levels of phosphorus, parathyroid hormone, and calcium and risks of death and cardiovascular disease in individuals with chronic kidney disease: a systematic review and meta-analysis显示文摘 | Palmer SC Hayen A Macaskill P | 2011 | JAMA2011,305,11: | 1 |
| 19 | The MoCA: well- suited screen for cognitive impairment in Parkinson disease显示文摘 | Dalrymple - Alford J C MacAskill M R Nakas C T | 2010 | Neurology2010,75,19: | 1 |
| 20 | Meta-analysis of the impact of surgical margins on local recurrence in women with early- stage invasive breast cancer treated with breast conserving surgery 显示文摘 | Houssami N Macaskill P Marinovich ML | 2010 | EurJCancer2010,46,18: | 1 |