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| 1 | Relation of the IGF/IGF1R system to autophagy in colitis and colorectal cancer显示文摘Metabolic syndrome(Met S), as a chronic inflammatory disorder has a potential role in the development of inflammatory and cancerous complications of the colonic tissue. The interaction of DNA damage and inflammation is affected by the insulin-like growth factor 1 receptor(IGF1 R) signaling pathway. The IGF1 R pathway has been reported to regulate autophagy, as well, but sometimes through a bidirectional context. Targeting the IGF1 R-autophagy crosstalk could represent a promising strategy for the development of new antiinflammatory and anticancer therapies, and may help for subjects suffering from Met S who are at increased risk of colorectal cancer. However, therapeutic responses to targeted therapies are often shortlived, since a signaling crosstalk of IGF1 R with other receptor tyrosine kinases or autophagy exists, leading to acquired cellular resistance to therapy. From a pharmacological point of view, it is attractive to speculate that synergistic benefits could be achieved by inhibition of one of the key effectors of the IGF1 R pathway, in parallel with the pharmacological stimulation of the autophagy machinery, but cautiousness is also required, because pharmacologic IGF1 R modulation can initiate additional, sometimes unfavorable biologic effects. | Ferenc Sipos Hajnal Székely Imre Dániel Kis Zsolt Tulassay Gyorgyi Muzes | 2017 | World Journal of Gastroenterology2017，23，46： | 9 |
| 2 | The insulin-like growth factor system:IGFs IGF-binding proteins and IGFBP-proteases显示文摘 | LEIBACH A MUZES G FEHER J | | 0，，02： | 1 |
| 3 | Comparison of the effects of 1,25 dihydroxyvitamin D and 25 hydroxyviamin D on bone pathology and disease activity in Crohn' s disease patients显示文摘 | Miheller P Muzes G Hritz I | | 0，，： | 1 |
| 4 | The insulin-like growth factor system:IGFs,IGF-binding proteins and IGFBP-proteases显示文摘 | Lelbach A Muzes G Feher J | 2005 | Acta Physiol Hung2005，92，2： | 1 |
| 5 | Current perspectives of cata-bolic mediators of cancer cachexia显示文摘 | Lelbach A Muzes G Feher J | | 0，，09： | 1 |
| 6 | Regeneration associated growth factor receptor and epithelial marker expression in lymphoid aggregates of ulcerative colitis显示文摘 | Sipos F1 Muzes G Valcz G | 2010 | Scand J Gastroenterol2010，45，4： | 1 |
| 7 | The insulin-like growth factor system: IGFs, IGF-binding proteins and IGFB-proteases 显示文摘 | LELBACH A MUZES G FEHER J | 2005 | Acta Physiol Hung2005，92，2： | 1 |
| 8 | The insulin-like growth factor system:IGFs,IGF-binding proteins and IGFBP-proteases显示文摘 | Lelbach A Muzes G Feher J | 2005 | Acta Physiol Hung2005，92，2： | 1 |
| 9 | Immunomodulator effect of silymatin therapy in chronic alcoholic liver diseases显示文摘 | Deak G Muzes G Lang I | 1990 | Orv Hetil1990，131，24： | 1 |
| 10 | The insulin-like growth factor system: 1GFs, 1GF-binding proteins and 1GFBP-proteases 显示文摘 | Lelbach A Muzes G Feher J | 2005 | Acta Physiol Hung2005，92，2： | 1 |
| 11 | Currentperspectivesof catabolic media-tors of canercachexia显示文摘 | LelbachA Muzes G Feher J | 2007 | Med Set Monit2007，13，9： | 1 |
| 12 | lnteraetinn of autophagy and Toll-like receptors: a regulatory cross-talk-even in cancer eells? 显示文摘 | Muzes G Constantinovits M Furi I | 2014 | Curr Drug Targets2014，15，8： | 1 |
| 13 | Comparison of the effects of 1,25 dihydroxyvitamin D and 25 hydroxyvitamin D on bone pathology and disease activity in Crohn's disease patients 显示文摘 | MIHELLER P MUZES G HRITZ I | 2009 | Inflamm Bowel Dis2009，15，11： | 1 |
| 14 | Randomized trial of artesunate+amodiaquine, snlfadoxine-pyrimethamine+amodiaquine, chlorproguanal-dapsone and SP for malaria in pregnancy in Tanzania显示文摘 | Mutabingwa TK Muze K Ord R | 2009 | PLoS One2009，4，4： | 1 |
| 15 | Effect of the natural bioflavonoid antioxidant silymarin on superoxide dismutase (SOD) activity and expression in vitro显示文摘 | Lang I Deak G Muzes G | 1993 | Biotechnol Ther1993，4，34： | 1 |
| 16 | Comparison of the effects of 1,25 dihydroxyvitamin D on bone pathology and disease activity in Crohn's disease patients 显示文摘 | Miheller P Muzes G Hritz I | 2009 | Inflamm Bowel Dis2009，15，11： | 1 |
| 17 | Muhicentric Castleman's disease: a challenging diagnosis显示文摘 | Muzes G Sipos F Csomor J | 2013 | Pathol Oncol Res2013，19，3： | 1 |
| 18 | Current perspectives of catabolic mediators of cancer cachexia显示文摘 | Lelbach A Muzes G Feher J | 2007 | Med Sci Monit2007，13，9： | 1 |
| 19 | Regeneration associated growth factor receptor and epithelial marker expression in lymphoid aggregates of ulcerative colitis显示文摘 | SIPOS F MUZES G VALCZ G | 2010 | Scand J Gastroenterol2010，45，： | 1 |
| 20 | The insulin-likegrowthfaetor system : IGFs, IGF - binding proteins and IGFBP - proteases 显示文摘 | Lelbaeh A Muzes G Feher J | 2005 | Aeta Physiol Hun2005，92，2： | 1 |
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